ABSTRACT BACKGROUND: Cardiac surgery is the definitive intervention for structural heart diseases particularly of congenital aetiology in children. Unfortunately, most developing countries currently lack adequate capacity for pediatric cardiac surgery often necessitating referral to foreign countries with appropriate facilities and capacities. We hereby report the in-hospital outcome of Nigerian children referred from Lagos University Teaching Hospital to undergo cardiac surgery abroad. METHO...
ABSTRACT Human immune deficiency virus (HIV) seroprevalence among pregnant women in Calabar was studied. The aims were to establish HIV seroprevalence rate and to identify factors which influence this rate in our pregnant women. HIV seroprevalence rate of 2.7% among antenatal women in Calabar was recorded with a vertical transmission rate of 20%. Husband and wife not living together, history of induced abortion and blood transfusion significantly increase HIV seroprevalence rate among antenat...
SUMMARY Vertical infection by the Human Immunodeficiency Virus (HIV) among two consecutive pair of twins from a well to do family is presented. While the first twin of the first pair must have been infected in-utero, the second may have been infected at parturition of through breast milk. Severe protein-energy malnutrition was the main mode of presentation. A recommendation is made for routine screening of pregnant women during ante-natal care with family planning counselling of positive case...
ABSTRACT This study evaluated the efficacy of dihydroartemisinin (DHA), mefloquine (MQ) chloroquine (CQ) and combination of DHA and MQ in children for the treatment of acute uncomplicated falciparum malaria, in Lagos. The toxic and histopathologic effect of DHA, MQ and CQ using animal model (mice) was also assessed. Finally, the efficacy of DHA, MQ, CQ, combination of DHA plus MQ and DHA plus CQ on P. berghei in mice was evaluated. Nine hundred and twenty patients aged between 3-13 years at...
ABSTRACT Extracts of Hibiscus sabdariffa (HS) are widely believed in folk medicine to be effective in the treatment of a variety of ailments. Aqueous extract of HS has been reported to decrease fluid and food consumption and weight gain in non-pregnant rats through mechanisms not yet fully understood. Thus when aqueous extract of HS is administered to pregnant and lactating animals, it may lead to decreased food consumption and consequently, malnutrition in these animals. Maternal malnutriti...
ABSTRACT Congenital heart defects (CHD) remain one of the most common categories of birth defects worldwide. In many developing countries, high early childhood mortality and limited diagnostic facilities often obscure the true scope of the problem. In this review, we provide an overview of the clinical epidemiology and management of CHD in a developing country: Nigeria, Africa's most populous country. We describe the types of CHD and the clinical presentation, echocardiographic diagnosis, man...
ABSTRACT The probability of developing tuberculosis (TB) disease is higher in immune compromised subjects such as HIV/AIDS patients. Conventional methods of diagnosing TB which include sputum smear microscopy, culture and chest X-ray have drawbacks and established limitations. The limitations are pronounced in immunocompromised subjects. The consequence of poor diagnosis of TB especially in resources limited environment like Nigeria contributes to the rising incidence of TB. Introducing immu...
The advent of Corona virus; its origin, historical background, global impact, conspiracy theories, remedies and the way forward.
ABSTRACT The main reason that brought the scope of developing medical diagnosis support system for life style diseases is the high death rate and huge amount of people suffering from such diseases. The system is a web based application developed using PHP, JavaScript and MySQL database using Adobe Dreamweaver CC 2018 software and XAMPP. The study was conducted weather it was feasible to come up with a system in terms of economic, technological, operational and social standings and it was dete...
ABSTRACT In the last decade, the prevalence of malaria has been escalating at an alarming rate, especially in Africa. A recent estimate of malaria incidence derived from routine surveillance data suggest 174 million episode occurred in African region in 2011 with estimated deaths of 596,000 (WHO, 2011). Malaria has been estimated to cause 2.3% of global disease and 9% of disease in Africa (WHO, 1997); it ranks third among major infectious disease threats in Africa after pneumococcal acute res...
ABSTRACT Herbal medicines are an important part of the culture and traditions of African people. Today, most of the population in urban Nigeria, as well as rural communities, rely on herbal medicines for their health care needs. Epidemiological data suggest that lower incidences of certain chronic diseases such as atherosclerosis, arthritis, diabetes, acquired immune deficiency syndrome (AIDS) mediated by the human immunovirus, asthma, neoplasia, neurodegenerative and cardiovascular diseases ...
ABSTRACT Plants continue to be a major source of medicines as they have been throughout human history. A 2008 report from the Botanic Gardens Conservation International (representing botanic gardens in 120 countries) revealed that 5 billion people still use medicinal plants to partly cater for their health care needs. According to the World Health Organization, medicinal plants would be the best source of a variety of drugs (Toroglu, 2011). The fact that plants synthesize a wide variety of ch...
ABSTRACT An estimated 25-30 million women become pregnant annually in malaria-endemic areas of Africa; most of them live in areas of stable malaria transmission (WHO, 2004). The immunosuppression associated with pregnancy and the absence of specific immunity to the unique subset of P. falciparum that sequester in the placenta, especially in primigravidae, have been adduced as reasons for the increased susceptibility of pregnant women to malaria infection (Fried and Duffy, 1996; Hviid and Sal...
abstract this paper analyses the generation and management of waste electronic waste generated in the households of harare and muture. current studies is solid waste management have focused on the waste management practices of general municipal solid waste.