Chemical Engineering Research Papers/Topics

Fast, reconfigurable switch for paper microfluidics

A method to create smart and flexible switches for the regulation of liquid flow across multiple channels is essential in paper microfluidics. Prior approaches are hampered by long response times, high actuation fluid volumes, and external control circuitry. To diminish these problems, we designed a distinctive actuator device fashioned entirely from chromatography paper and featuring folds. The fold can be selectively wetted by an actuation fluid at either the crest or trough, resulting in t...

Microfluidics to identify drug dose response and LD50 of parasites

The emergence of new drugs is often driven by the escalating resistance of parasites to existing drugs and the accessibility of more advanced technology platforms. Microfluidic devices have allowed for quicker testing of compounds, regulated sampling/sorting of entire animals, and automated behavioral pattern detection. In the majority of microfluidic devices, the effects of drugs on small animals (e.g. Caenorhabditis elegans)elegant are quantified by an endpoint, dose response curve that sho...

Droplet Actuator Patent

Apparatus , methods , and systems for automated liquid drop let manipulation include an open droplet supporting surface. An actuator can translate the surface in space with at least one degree freedom of movement to influence movement of one or more droplets on the surface . In one embodiment , the surface is patterned with areas that attract the droplets and interstitial areas that repel the droplets to enhance transport of droplets . For example , for water - based droplets the attr...

Sweat Sensors for Human Medicine - A Review

In recent years, there has been significant interest in developing wearable devices to mimic the integrated sensing of life forms, which enhances their performance and survival capabilities. Progress in the development of physical sensors and wearable electronics has been promising, leading to numerous consumer products that measure activity, posture, heart rate, respiration rate, and blood oxygen level. Despite the challenges in retrieving and processing bodily fluids, wearable chemical sens...

Magnetic Field effects on Saccharomyces cerevisiae for bioethanol production

Previous studies have produced mixed results on the influence of magnetic fields on the fermentation kinetics and growth of various types of Saccharomyces cerevisiae. We carried out two experiments to assess the role of magnetic fields on cell growth and ethanol production during fermentation. The first of these experiments took place for 25 h, with a dextrose loading rate of 2%, and the magnetic fields were both homogeneous and non-homogeneous with intensities of 100 and 200 mT. The second e...

Fast reconfigurable paper switch for chemical sensing applications

A method to create smart and flexible switches for the regulation of liquid flow across multiple channels is essential in paper microfluidics. Prior approaches are hampered by long response times, high actuation fluid volumes, and external control circuitry. To diminish these problems, we designed a distinctive actuator device fashioned entirely from chromatography paper and featuring folds. The fold can be selectively wetted by an actuation fluid at either the crest or trough, resulting in t...

Droplet Platform for Actuation and Chemical Mixing of Multiple Droplets

An open microfluidic system has been developed to dispense and manipulate individual droplets on plastic sheets. Superhydrophobic material is applied to the surface of obtainable plastic sheets by spraying, then hydrophilic symbols are printed with an inkjet printer. The plastic sheets are connected to a two-axis tilting platform driven by stepper motors, which produces mechanical agitation enabling droplet transport. The system has been demonstrated to carry out various droplet operations, s...

Agar Membrane Chip for Imaging Roundworms and Drug Testing

In this paper, we explore the use of microfluidic paper-based analytical devices (lPADs) to study the behavior of Caenorhabditis elegans. We show how these devices can be fabricated on paper and plastic substrates, as well as how to load, visualize, and transfer single and multiple nematodes. We also demonstrate the use of anthelmintic drug, levamisole, to perform chemical testing on C. elegans. Furthermore, we provide a custom program that is able to recognize individual worms on the lPADs i...

CFU Imaging and Counting for Bacterial Studies

Bacterial populations grown in a lab environment are typically seen as homogeneous in terms of growth rate, size, and content. However, recent findings have shown that even during exponential growth phase, these cells can be heterogeneous. This has important consequences for how bacteria respond to stressors such as antibiotics. For example, the concept of antimicrobial persistence is linked to a small subpopulation of cells that enter a dormant state where antibiotics are no longer effective...

Fluidized Bedreactor Modelling and Simulation with ASPEN Plus for Alumina (AL2O3) Production Systems.

Abstract Fluidized bed reactor is useful for heterogeneous (multi phase) reactions, separations, size enlargement, coating, and blending in chemical and pharmaceuticals industries. To develop a model and simulation of this reactor with advanced systems process engineering software (Aspen Plus). Aspen plus has the capability to simulate real factory performance, design improved plants, and intensify profitability in present plants. This modeling and simulation are applied Geldart B particle cl...

COVID-19 Virus Repellent Solution Based on the Liquid Electric Air Sanitization

Indubitably the most challenging coronavirus (Covid-19) outbreak, caused by SARS-CoV-2. With the number of Covid-19 cases now approaching millions globally so, for controlling the current infection rate, we have come up with this innovation of virus repellent electric liquid vaporizer means by vaporization of the solution which is the in-liquid form by means of electricity, which will enable the infectious virus and bacteria to be less effective also it will sometime kill the virus in a small...

Fluidized Bedreactor Modelling and Simulation with Aspen Plus for Alumina (AL2O3) Production Systems

Abstract:Fluidized bed reactor is useful for heterogeneous (multiphase) reactions, separations, size enlargement, coating, and blending in chemical and pharmaceuticals industries. To develop a model and simulation of this reactor with advanced systems process engineering software (Aspen Plus). Aspen plus has the capability to simulate real factory performance, design improved plants, and intensify profitability in present plants. This modeling and simulation are applied Geldart B particle cla...

Determination Of Surface Charge Density Of Α-Alumina By Acid - Base Titration

ABSTRACT . The surface charge density (σo) of colloidal alpha-alumina suspended in various 1:1 electrolytes was measured using acid-base titration. An auto titrator capable of dispensing accurately 25 ± 0.1 µL of titrant was used. The pH and temperature in the titration cell were monitored using single-junction electrodes and platinum resistance thermometers, respectively. A constant supply of nitrogen gas in the cell was used to maintain inert conditions. The whole set-up was interfaced w...

Low Temperature Glycerolysis as a High FFA Pre-Treatment Method for Biodiesel Production

ABSTRACT A novel low-temperature glycerolysis process for lowering free fatty acid (FFA) in crude jatropha oil for alkali catalyzed transesterification has been developed. The response surface methodology (RSM) based on the central composite design was used to model and optimize the glycerolysis efficiency under three reaction variables namely; reaction time, temperature and glycerol to oil mass ratio. The optimum conditions for the highest glycerolysis efficiency of 98.67% were found to be ...

Effects of Castor Oil on the Physical Properties of Polyether Based Flexible Polyareahane Foam

ABSTRACT A preliminary study was made on the effect of castor oil on the properties of polyether based polyurethane foam such as rising time, density, hardness tensile strength, compression, elongation and heat aging. The castor oil was introduced into the polyurethane foam by partially substituting it for silicone oil through seven experimental set up, based on the laboratory mix formulation on 5OOg polyether based polyol with 0%, 20%, 40%, 50%, 60%, 80% and IOO% castor oil substitutions.


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