ABSTRACT This study investigated the antimicrobial and wound healing properties of leaf extracts and ointment formulations of Spermacoce verticillata Linn (Family: Rubiaceae). Three different solvents: acetone, ethanol and water were used in the extraction of phytochemicals from the leaves of Spermacoce verticillata. The bioactive constituents of acetone, aqueous and ethanol extracts were determined using standard phytochemical analytical methods. The cup plate agar diffusion method was ...
ABSTRACT The solubility of gentamicin in various formulation vehicles (oils, surfactants and co-surfactants) was determined using the shake flask method. Emulsifying ability of the surfactants for the selected oil was screened. Different SNEF prototypes were developed following the construction of ternary phase diagrams using water titration method. The effect of drug and other additives on the ternary phase diagrams were studied and the selected formulations were optimized. Optimized formul...
ABSTRACT The solubility of gentamicin in various formulation vehicles (oils, surfactants and co-surfactants) was determined using the shake flask method. Emulsifying ability of the surfactants for the selected oil was screened. Different SNEF prototypes were developed following the construction of ternary phase diagrams using water titration method. The effect of drug and other additives on the ternary phase diagrams were studied and the selected formulations were optimized. Optimized formul...