Research Papers/Topics in Pharmacy

Biosynthesis of Silver Nanoparticles (AGNPS) Using Spondias Mombin Extract as a Bioreducing Agent

The field of nano science plays a crucial role in modern research and technology, offering unparalleled opportunities for innovation. Spondias mombin extract is used in this study as a bioreducing agent for the biosynthesis of silver nanoparticles (AgNPs). The properties of these nanoparticles are compared. As the color of the extract changed from colorless to brown and then dark silver during synthesis, the reduction of AgNO3 confirmed the effectiveness of S. motherbin extract as a bio-reduc...

Assessment of Heavy Metal Contents in Selected Herbal Medicines in Nigeria

The use of herbal medicines, despite the advancement in production of orthodox ones, has been on the increase, both in underdeveloped, developed and developing countries like Nigeria in particular. The approval of these herbal remedies by regulatory bodies like the National Agency for Food and Drug Administration Control, (NAFDAC) in Nigeria has further encouraged the use of herbal remedies by almost everybody. This research targets the estimation of the concentration of‘heavy metals’ in ...

Improving Stroke Prevention and Quantifying Outcomes Using a United States' City Model: Intervention Measurement through Population Survey and Hospital-Based Study

PROPOSAL: ABSTRACT Background: Currently stroke represents a serious problem in public health as one of the leading causes of mortality and morbidity worldwide [1-3] with developing countries accounting for 85% of global deaths from stroke [1, 3-5]. A very good example explains how stroke seems to be increasing in Nigeria and the case fatality is unacceptably high [6]. Good perceptions and knowledge of stroke; a population’s knowledge of the stroke risk factor profiles, and good quality...

Development of Lipid-Based Microsuspensions for Ophthalmic Delivery of Gentamicin

ABSTRACT The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human eye, extending contact time of drug with the cornea, increasing the penetration through the complex anatomical structure of the ey...

Assessment of Knowledge On Use of Artemether Lumefantrine in Management of Uncomplicated Malaria Among Outpatients at Klu-Th

ABSTRACT This study sought to assess the knowledge on the use of Artemether/ therapy in the management of uncomplicated malaria among out patients treated at KlU-TH. A cross sectional study design was employed in this study. Data was collected from August to October 2018 using a questionnaire by simple Random sampling and was entered and analyzed using Microsoft Excel spread sheet and Statistical Package of Social Sciences (SPSS) version 20 respectively. The results were presented in form of ...

Pharmaco-Economic Analysis of Brands of Antacid Formulations Available in Ishaka Town Using Titrimetric Method

ABSTRACT Pharmaco-economics involves comparing the cost and consequences of products and services and Cost-effectiveness is the relationship between cost and effectiveness of a given drug. ANC of an antacid is one of the ways of evaluating effectiveness of antacid brands. ANC (mEq per unit dose) is the ability of the antacid to neutralize gastric acid (Shery et al., 2013), and it should be greater or equal to 5mEq per unit dose(FDA), where a unit dose of 0.5g for tablets and 5ml for suspensio...

Comparative Pharmacopoeia Analysis of Selected Brands of Diclofenac Sodium Tablets Available in Western Uganda Pharmacies based On Bp 2009

ABSTRACT Jackground: Diclofenac is one of the most commonly used non-steroidal anti-inflammatory lrugs (NSAIDs) for the treatment of pain, rheumatism and other inflammatory conditions.Aim: ~his study aimed to investigate whether the selected brands of diclofenac sodium meet heir label specifications as well as the BP 2009.Materials and Methods: Three brands of )iclofenac sodium were randomly selected in Pharmacies of Ishaka-Bushenyi Municipality, lushenyi. A total of 20 tablets of each brand ...

Assessment of The Chemical Composition and Pesticide Properties of Cassia Didymobotrya Ash on Myzus Persicae Affecting Tomato Crops in Ishaka

ABSTRACT Background: Myzus pe.rsicae (green peach aphids) are crop pests; they are among the most destructive insect pests on cultivated plants in temperate regions. Many of them are green in color, but others may be white wooly or black (McGravin,1993).Their damage to plants has made farming a complicated venture across the whole world. From the zo9logical standpoint, they are a highly successful group of organisms (Piper, 2007). The study was conducted to evaluate .the chemical composition ...

New Combination Methods of Detecting Drug Interaction And Monitoring Adverse Drug Reactions in "Close System Pharmacy"

ABSTRACTPharmacovigilance is an essential phenomenon in the rational use of medicine, providing information about ADR in general population. Tracking ADR in" close system pharmacy" whichhas relied on use of yellow forms and feed back following exposure to drugs has been inadequate. Alternative methods are therefore required. In the present study, the use of a combination of two methods to determine possible interactionsprior to dispensing and adverse drug reactions following ex...

Investigation of Antibacterial Activity, Phytochemical Screening and The Extractive Value of Different Solvents On Lawson/A Inermij(Henna) Plant Leaf Extract.

ABSTRACT. The purpose of this study was to evaluate the antibacterial activity, to determine the most efficiency extractive solvents and phytochemical profile of Hot water, Methanol alcohol and Lemon juice extract of Lawsonia inermis (henna) leaf. The plant attracted the attention of researchers because of its use as anti-infective agent. The oily and alcoholic extracts of the plant Lawsonia inermis dried powdered leaves were separately obtained by maceration, while the aqueous was obtained b...

Antibiotic Sensitivity Patterns of Staphylococcus Aureus to Methillicin in Clinical Samples at Kid Teaching Hospital.

ABSTRACT Back ground: Staphylococcus aureus is a gram positive bacteria that exists on the skin as nonnal flora. It is classified as Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin-sensitive Staphylococcus aureus (MSSA), where MRSA is resistant to beta-lactam antibiotics. MRSA has become a predominant pathogen in the health care system causing outbreaks within the communities and hospitals. The infection risk of mortality and increases morbidity. Objective: To detennine the...

Factors Affecting Utilization of Focus Antenatal Care Services Among Pregnant Mothers Attending Antenatal Care in Kitagata Hospital-sheema District, Uganda.

ABSTRACT Background: In Low and Medium income countries (LMICs) focus antenatal care (FANC) services are so low, below the recommended threshold. In Uganda, high maternal and neonatal mortalities have been attributed to the severe variations in F ANC coverage in rural communities. Aim: This study was to determine factors affecting utilization of FANC services in Kitagata Hospital of sheema district, Uganda. Materials and Methods: This was a cross-sectional study carried out for a period of 5 ...

Determination of Antidotal and Protective Properties of Elaeis Oleifem Frult Extract in Orally Organophosphate Poisoned Albino Rats

TABLE OF CONTENT DECLARATION ............................................................................................................................. i DEDI CA TI 0 N ................................................................................................................................ i i A C K N 0 W LEDG EM ENT ............................................................................................................. iii TA 8 LE 0 F C 0 NTENT ...............

Phytochemical Screening, Quantification and the Anti-Inflammatory Activity of the Methanolic Extract of Ocimum Gratissimum Leaves

CHAPTER ONE 1.0 INTRODUCTION Medicinal plants have been of great important to the health of individual and communities. The medicinal value of these plants had some chemical active substances that produce a definite physiological action on the human body. Nature has served as a rich repository of medicinal plants for thousands of years and an impressive number of modern drugs have been isolated from natural sources, notably of plant origin (Cowan, 1999) .Herbal medicine. based on their tradi...

Phytochemical Screening, Quantification, and Fractionation of Aqueous Methanolic Extract of Spathodea Campanulata Stem Bark

ABSTRACT: Plants produce a good deal of secondary metabolites which have benefited mankind in various ways including treatment of diseases. The present study was carried out to identify and isolate the different phytochemicals present inS. campanulata stem bark aqueous methanolic extract, to quantify these phytochemicals, and to identify different fractions of the extract of S. campanulata. The study carried out was an experimental one, done at Kampala International University Western Campus...


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