Applied Chemistry Research Papers/Topics

Simulated Modeling: Contrasting Ca/Mg And Mn+-natural Organic Matter Competitive Complexation In Water

Complexing capacities of calcium and magnesium with natural organic matter (NOM)/selected organic chelating agents, in the presence and absence of other major and trace cations in water, were studied by anodic and cathodic square wave stripping voltammetry techniques (ASWSV and CSWSV). Under predetermined and optimized physico-chemical parameters (pH, temperature and ionic strength), calcium-NOM complexation and competitive complexation by other elements of known concentration (Pb, Zn, a...

Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques

Abstract The need to come up with new and novel antibiotics that utilize unique mechanisms, to which bacteria cannot generate resistance, was the main motivation of this study. Tyrocidine peptides are non-selective antibiotics that have such properties. However, very limited information is available about their mechanism of action. The aim of this study was to determine the mechanism of action of tyrocidine peptides, tyrocidine A, tyrocidine B and tyrocidine C. Chapter 3 explored the structur...

Comparative Studies And Synergistic Effect Of Senna Alata, Ricinus Communis Leaves And Lannea Barteri Stem Bark Extracts And Their Formulation On Pathogenic Bacteria And Fungus

ABSTRACT Three medicinal plant parts, including the leaves of Senna alata, Ricinus communis and the stem bark of Lannea barteri were used for the current study. The aim was to investigate the antimicrobial effect of the crude extracts alone, their combinations and the crude extracts formulated individually with polyethylene glycol (PEG) and Shea butter, as well as phytochemical screening of the medicinal plants crude extracts. The microorganisms employed in this study were E. coli, S. aureus...

Mechanism For The Adsorption Of Mucin On Hydroxyapatite

ABSTRACT The adsorptive ability of mUCIn onto hydroxyapatite was evaluated based on its adsorptive amount and adsorptive strength. The adsorptive amount was determined by measuring the amount of mucin adsorbed onto hydroxyapatite while adsorptive strength was determined by measuring the amount of mucin remaining adsorbed after rinsing. The amount of mucin adsorbed onto the substrates in all cases followed the order Sigma grade HAP> synthesized HAP> CHP and generally increased with increa...

Immortalization Of B Cells From Plasmodium Falciparum Exposed Individuals For The Production Of P Arasite- Specific Antibodies

ABSTRACT The continuous production of antibodies with desired properties has become very important in fields, such as biomedical research and in medicine. Methods for making such useful antibodies include the hybridoma technology and Epstein-Barr virus (EBV) transformation of antibody- secreting cells (ASCs) to make them live longer in ex vivo culture. Transformed cells are then capable of multiplying rapidly over longer periods and producing large amounts of the desired antibodies. The aim ...

Synthesis Of A Quaternary Ammonium Salt From Epoxide And Fatty Amine And Evaluation Of Its Antimicrobial Properties

ABSTRACT Quaternary ammonium compound was synthesized from epoxy and fatty amine reaction. Fourier Transform Infrared(FTIR) spectrometric analysis of the starting materials, and the final product(N-benzyl-N,N-dioctyl-2-hydroxy-3 phenoxypropylammonium chloride) were conducted, and results showed a disappearance of sharp N-H peak of 2o amine, and appearance of broad O-H peak of alcohol in the spectrum of the final product. Mass spectrometric(MS)analysis of the final product was also conducted, ...


16 - 22 Of 22 Results