ABSTRACT Three species of garden egg namely Solanum aithiopicum, Solanum aubergine and Solanum anguivi processed into raw and boiled powdered flour, samples were taken for their nutritional and mineral components using standard analytical methods. Proximate composition determined include total ash, moisture content, crude fibre, crude protein, crude fat and carbohydrate by difference, the mineral components determined are P, Fe, Mg, Na, Mn, Zn, Ni and Cu. The proximate analysis (%) shows th...
ABSTRACT The synthesis of ten new alkynylated derivatives of angular phenoxazine and alkynylated naphthoquinone was thoroughly investigated. The first intermediate, 6-chloro-5Hbenzo[ a]phenoxazin-5-one was obtained by the condensation of 2-aminophenol with 2,3- dichloro-1,4- naphthoquinone in the presence of anhydrous sodium tricarbonate (IV) . Thereafter, the intermediate and 2,3-dichloro-1,4-naphthoquinone were each suggested to Sonogashira cross–coupling reaction under copper-, amine-, ...
ABSTRACT The concentration of six heavy metals and six of sixteen (16) US EPA priority polycyclic aromatic hydrocarbons (PAHs) in water, fish and sediment samples of the confluence of rivers Niger and Benue were investigated in triplicates using atomic absorption spectrophotometer (AAS) for the heavy metals determination and gas chromatography coupled with mass spectrometer detector for the PAHs after acid digestion of the samples for heavy metals,liquid-liquid and solid-liquid extracti...
ABSTRACT Magnetically recoverable Pd/Fe3O4-catalyzed Hiyama cross-coupling reactions of 6-Bromo-5H-benzo[a]phenothiazin-5-one, 6-Bromo-5H-naphtho[2,1-b]pyrido[2,3-e][1,4]oxazin-5-one and 11-Amino-6-bromo-9-thio-5H-naphtho[2,1-b]pyrimido[5,4-e][1,4]oxazin-5-one (as intermediates) with 2-(Dimethylsilyl)pyridine and Dimethyl(2-thienyl)silanol were investigated. The intermediates were prepared by the reactions of 2-Aminothiophenol, 2-Aminopyridin-3-ol and 4,5-Diamino-6-hydroxylpyrimidin-2-t...
ABSTRACT The roots of Dennettia tripetala and Milicia excelsa were analyzed for the presence of phytochemicals. Five different solvents, which include methanol, ethanol, ethyl acetate, butanol and water, were used for the extraction of the phytochemicals.The root of Dennettia tripetala contained alkaloids, terpenoids, flavonoids, saponins, phenols, steroids and glycosides in varying degrees of abundance in the different solvents with tannins not detected in all the solvents. Milicia excelsa...
ABSTRACT Tandem amidation catalyzed synthesis of linear diazaphenoxazine carboxamide derivatives is reported. This was achieved by the reaction of 2-amino-3-hydroxypyridine and 2,3,5-trichloropyridine in aqueous basic medium which gave 3-chloro-1,9-diazaphenoxazine as white solid crystals. 3-Chloro-1,9-diazaphenoxazine was then subjected to Buchwald-Hartwig amidation coupling reaction with various amides namely formamide, phthalamide, 4- nitrobenzamide, benzamide and acetamide via water prom...
ABSTRACT The synthesis of ten new alkynylated derivatives of angular phenoxazine and alkynylated naphthoquinone was thoroughly investigated. The first intermediate, 6-chloro-5Hbenzo[a]phenoxazin-5-one was obtained by the condensation of 2-aminophenol with 2,3- dichloro-1,4- naphthoquinone in the presence of anhydrous sodium tricarbonate (IV) . Thereafter, the intermediate and 2,3-dichloro-1,4-naphthoquinone were each suggested to Sonogashira cross–coupling reaction under copper-, amine-, a...
ABSTRACT The Schiff base ligand, 2-[(E)-[{3--[(2-hydroxybenzylidene)amino]phenyl}imino)methyl]phenol was synthesized by condensing 1,3-diaminobenzene and 2-hydroxybenzaldehyde in absolute ethanol. Its Cr(III) and Cr(VI) complexes were equally synthesized. The ligand was characterized via UV, IR and NMR spectroscopy, whereas the complexes were characterized based on UV and IR spectroscopy and conductivity values. Stoichiometric studies indicated 1:1 metal to ligand ratio for both complexes. C...
ABSTRACT The azo-ligand, 1,5-dimethyl-2-phenyl-4-[(E)-(2,3,4-trihydroxylphenyl) diazenyl]- 1,2-dihydro-3H-pyrazol-3-one (H3L) and its Zn(II) and Cd(II) complexes have been synthesized and characterized based on stoichiometric, molar conductance, electronic and infra-red spectral studies. The results showed that H3L reacted with the metals in 2:1 ratio. H3L coordination was through the hydroxyl, azo and carbonyl groups to form [Zn(H2L)2] 2+ and [Cd(H2L)2] 2+ respectively. Solvent extraction s...
ABSTRACT Five species of Mushroom namely Termitomyces robustus, Agaricus bisporus, Pleurotus tuber-regium, Amanita phalaoides and Amanita verosa were collected from eleven locations in Uke, Abatete, Ideani, Nnobi, Nnewi (Okpuno-egbu), Nnewi (Umudim) and Ozubulu between 2009 and 2012 in Anambra State, Nigeria. They were kept in clean collection bags and identified by a taxonomist. Some of the mushroom samples were later oven dried at 75 0 C for 4 hours and kept for chemical analysis while some...
ABSRACT The purpose of this research work was to examine drug release agents and the several delivery systems for which both natural and synthetic polymers have been employed for their design and fabrications. Under these facts, a large number of delivery systems made from synthetic polymer materials were found to be non-biodegradable, non-biocompatible and thus tend to impose both adverse mechanical and physiological effects on man when consumed especially on respiratory proce...