Abstract Background: The absence of antibodies specific for the 19 kDa C-terminal domain of merozoite surface protein 1 (MSP119) has been associated with high-density malaria parasitaemia in African populations. The hypothesis that a high prevalence and/or level of anti-MSP119 antibodies that may inhibit erythrocyte invasion would be present in apparently healthy individuals who harbour a sub-microscopic malaria infection was tested in this study. Methods: Plasma samples were collected from...
Abstract The development of antibiotic-resistant pathogens due to the indiscriminate use of antibiotics has led to advocacy for the use of natural products in the treatment of fish diseases. The antimicrobial activity of methanolic and ethanolic extracts of walnut leaves and onion bulbs were evaluated against six pathogenic bacteria (Pseudomonas aeruginosa, Staphyloccocus aureus, Bacillus subtilis, Pseudomonas fluorescens, Escherichia coli, Samonella typhi) using the cup – plate method. Min...
ABSTRACT Dried, milled cassava and yam peels were inoculated separately with A. nigermidRhizopus sp in solid state. The changes in crude protein (CP), crude fibre (CF), neutral detergent fibre (NDF), acid detergent fibre (ADF) and hemiccllulose were evaluated til 0. 4. X, and 10 days after inoculation. At. the end of the 10th day of fermentation with A. niger the crude protein of cassava peel meal (CPM) increased from 3.5% to 7.0% while that inoculated with Rhizopus sp increased to 5.25%. Cru...
ABSTRACT Ficus plant components have application in traditional medicine because of the myriad uses they have been subjected to. The ease of application is based on the secondary metabolites this plant contains. The challenges faced by modern medicine especially in the complete cure of microbially-associated diseases through abrupt and unpredictable genetic mutations in the presence of conventional drugs informed the investigation of the microbial inhibitory activities of the stem, root and l...
ABSTRACT Anopheles gambiae, the major Afro-tropical malaria vector is resistant to pyrethroid insecticide and this is threatening the impact of malaria control efforts using insecticides. In this study, the major malaria vector species from stagnant water bodies and their susceptibility status to pyrethroid insecticide was determined in some areas of Lagos state, Nigeria. Anopheles larvae were sampled from three areas of Lagos, namely Akoka, Idiaraba and Okobaba and raised to adulthood in the...
ABSTRACT One of the main challenges for clinical practice and public health surveillance is rapid and accurate identification of food borne pathogens. In Nigeria, the use of sophisticated molecular tools for foodborne pathogens detection has not been extensively adopted. Bacterial strains isolated from food products sold in Lagos, Nigeria, were subjected to phenotypic techniques and 16S rRNA gene sequencing for specie level identification. Bacterial identification was performed using colonial...
Human Ureaplasma had one species known as Ureaplasma urealyticum but was recently seperated into 2 species
ABSTRACT We evaluated the prevalence and association of Genital Ulcer Diseases among HIV-1 infected female commercial sex workers in Ibadan Nigeria.
ABSTRACT Batches of Schistosoma mansorti miracidia were irradiated with ultraviolet light for varying time intervals to determine the -influence of radiation on the transmission potential of radiated miracidia. There was a decrease in the survival rate of hatched-free swimming miracidia that corresponded with the increasing radiation exposure time. The activity rate of radiated miracidia also decrease with increasing radiation exposure time, showing a 69.3% reduction in the mean rate of move...
ABSTRACT Free-range chickens are sentinels for the presence of Toxoplasma gondii oocysts in the environment because they feed from ground. T. gondii infected chickens are also an important source of infection for cats that shed environmentally resistant oocysts after eating infected chicken tissues. We surveyed 50 free-range chickens from Oyo State, Nigeria for the presence of T. gondii antibodies using the modified agglutination test (MAT). All chickens tested seropositive with MAT titers of...
ABSTBACT This study evaluated the association of HXV-1 infection with some other sexually transmitted diseases (STDs) among femaIe commercial sex workers. BIood samples were collected from 250 female commercial sex workers in Ibadan Oyo State, Nigeria and tested for the presence of HEV antibodies using ELJSA and Western blot. Endocervical and high vaginal swab samples were also collected for microscopy and culture. The prevaIence of HIV-1 infection among CSWs in Ibadan, Nigeria was 25.6% wit...
ABSTRACT Herbal medications are becoming increasingly popular but a most-extraordinary claim by traditional/herbal medical practitioners relates to a Gram-positive bacterium, Staphylococcus, which has been depicted as a deadly sexually transmitted disease that manifest in the form of worms and other symptoms; with contributory roles including infertility, sexual dysfunction and impotency. They further boasted that they are the only ones that possessed the remedy (herbal) for the Staphylococcu...
ABSTRACT Herbal medications are becoming increasingly popular but a most-extraordinary claim by traditional/herbal medical practitioners relates to a Gram-positive bacterium, Staphylococcus, which has been depicted as a deadly sexually transmitted disease that manifest in the form of worms and other symptoms; with contributory roles including infertility, sexual dysfunction and impotency. They further boasted that they are the only ones that possessed the remedy (herbal) for the Staphylococc...
ABSTRACT Nigeria was ranked 14th in global assessment of under-five mortality rate due to infants poor nutrition. (The Punch 2011) The Wheat, genus Triticum, tribe,Triticeae family, is limiting in lysine but has adequate amount of sulphur-containing amino acids (Adeyeye & Aye 2005).The cultivation of Triticum durum yields well in Nigeria. It is mainly consumed by adults who eatit in bread and other pastries (The Compass 2011).There have been cases of hypersensitive response to wheat gluten ca...
An average Nigerian household consumes vegetables of various kinds but are ignorant of their antibacterial properties and other benefits. There is also an increase in the prevalence of multidrug resistant strains of bacteria which has raised the spectra of untreatable bacterial infections. This challenge has requested for urgency to search for new infection-fighting strategies. This study therefore investigated the antibacterial activities of the ethanolic and acetonic leaf extracts of Solane...