Pharmaceutical Microbiology Research Papers/Topics

Molecular Detection Of Extended- Spectrum Beta-Lactamases And Mcr-1 Genes In Gram Negative Isolated From Patient Of Urinary Tract Infections In Khartoum State

Abstract This study aimed to detect extended specterum beta lactamase genes in Gram negative bacteria associated with Urinary Tract Infections in Khartoum State. Ninty one urine specimens were collected in this study. Samples were cultured on CLED agar and bacteria were identified by the conventional biochemical methods. Modified Kirby-Bauer method was usedfor sensitivity testing by using the following antibiotics: Gentamicin, Ciprofloxacin, Co-trimoxazole, Imipenem and Ceftazidime. A total ...

Preformulation Studies Of Cyperus Esculentus Starch Used As Disintegrant And As Binder In The Production Of Paracetamol Tablets

ABSTRACT Starch is a naturally occurring polymer found in parts of the plants such as leaves, stems, tubers, and fruits. It is a commonly used excipient in pharmaceutical formulations because of its availability, affordability and inertness. Cyperus esculentus (tiger nut) is widely cultivated in the country especially in the northern part of Nigeria. Until recently, the use of tiger nut had been limited to food products and few pharmaceutical applications. This research is aimed at character...

Prevalence, Molecular Characterization And Antibiotic Susceptibility Of Reproductive Tract Pathogens Isolated From Women Of Child Bearing Age

ABSTRACT Reproductive tract infections (RTIs) are a major public health problem especially in the developing world. As part of measures to control the spread of these infections, the World Health Organization recommended syndromic management. This study set out to determine the prevalence patterns, molecular characteristics and antibiotic susceptibility of reproductive tract pathogens isolated from women of child bearing age with the aim of contributing useful information to policy formulati...

Evaluation Of Anti-Ulcer Properties Of Methanol Extract Of Terminalia Superba Engl. & Diels (Combretaceae) Stem Bark

ABSTRACT Terminalia superba Engl. & Diels (Combretaceae), is a member of the genus Terminalia that comprises around 100 species distributed in tropical regions of the world. In Africa it is found along the coast of west and central Africa. It has different uses in traditional medicine such as antimalarial, anti-diabetic, anti-fungal, and anti-hypertensive in the areas where it is found. Most of these uses are yet to be scientifically investigated. The powdered stem bark of Terminalia superba...

A Comparative Study of Modified Starches in Direct Compression Tabletting.

ABSTRACT S t a r c h e s have t r a d i t i o n a l l y been used i n t h e pharmaceutical i n d u s t r y as f i l l e r , binder and d i s i n t e g r a n t . Pharmaceutical grade s t a r c h e s a r e derived mainly f r o m maize g r a i n s and potato tubers. C u r r e n t advances i n t a b l e t t i n g technology, e s p e c i a l l y the use of high-speed, mu1 ti-station r o t a r y t a b l e t presses, and d i r e c t compression t a b l e t t i n g t e c h n i q u e s , have n e c e ...

A Comparative Study of Modified Starches in Direct Compression Tabletting

ABSTRACT S t a r c h e s have t r a d i t i o n a l l y been used i n t h e pharmaceutical i n d u s t r y as f i l l e r , binder and d i s i n t e g r a n t . Pharmaceutical grade s t a r c h e s a r e derived mainly f r o m maize g r a i n s and potato tubers. C u r r e n t advances i n t a b l e t t i n g technology, e s p e c i a l l y the use of high-speed, mu1 ti-station r o t a r y t a b l e t presses, and d i r e c t compression t a b l e t t i n g t e c h n i q u e s , have n e c e ...

Formulation And Evaluation Of Lipid Microparticle-Based Mosquito Repellent Cream

ABSTRACT In the tropics, malaria has become the most alarming public health problem, hence the need for a mosquito repellent, a personal protection against the vector. The concern about the deleterious effects associated with synthetic chemicals like N, N-diethy-3-methylbenzamide (DEET) has elicited the interest to explore plant materials as source of natural repellent for mosquito control. The aim of this study was to formulate and evaluate herbal mosquito repellent cream based on solid lip...

Use Of Prosopis Africana Seed Hydrolysate As Peptone Source For Microbial Growth Media

ABSTRACT There is a growing industrial demand for peptones of non-animal origin owing to legislations as well as outbreak of animal-associated diseases. Microbiological growth media developed from legumes as sources of protein hydrolysates are limited. It is, therefore, the aim of this study, to produce comparatively standard protein hydrolysates from Prosopis africanaseed that can be used as peptone for microbial culture in place of animal peptone. Prosopis africana seeds (2.5kg) were purch...

Antioxidant And Hepatoprotective Studies Of Annonasenegalensispers. (Annonaceae) Stem Bark.

Abstract The study was carried out to determine pharmacognostic standards, phytochemical constituents, evaluate the antioxidant and hepatoprotective activities of the extract and fractions of Annona senegalensis Pers. (Annonaceae) by employing both the in vitro and in vivo experimental models. The acute toxicity tests result showed the drug is safe at 5000mg/kg doses. The effect of DPPH free radical scavenging, ABTS radical scavenging, Hydroxyl radical scavenging, Hydrogen peroxide scavengi...

Urbanization And Symptomatic Malaria In Relation To Retroval Screening

ABSTRACT ;/ descript ive cross -, section analysis 0/ five hundred patients who were symptomatically diagnosed of malaria in three locations: Saki (peri-urban), Ibadan (urban) and Lagos (highly urbanized) were recruited /01' this study using a well structured questionnaire between September 2005 and June 2006. The prevalence 0/ both malaria and HIV infections were higher in Peri-Urban town than the other two locations. We observed that 80% were HIV positive in Saki. 20% in Ibadan and 37. J % ...