Research Papers/Topics in Laboratory Technology

Causes of blood culture contamination at Nelson Mandela Academic Hospital

Phlebotomy has been practiced for centuries and is still one of the most common invasive procedures in health care. Each step in the process of phlebotomy affects the quality of the specimen and is thus important for preventing laboratory error, patient injury and even death. For example, the touch of a finger to verify the location of a vein before insertion of the needle increases the chances that a specimen will be contaminated. This causes false blood culture results, prolonged hospitaliz...

Assessment of Total Serum Prostate Specific Antigen (TPSA), Anti Mullerian Hormone (AMH) Level among Sudanese Women with Polycystic Ovarian Syndrome

Abstract Back ground: Polycystic ovarian syndrome (PCOS) is one of the commonest endocrine disorders in women of reproductive age group, cause of androgen excess in women. (PSA) may be a new one diagnostic tool for PCOS. Serum AMH is synthesized by small antral follicles, which are precisely those seen on ultrasound and could help us to diagnose PCOS. The aim of this study to evaluate the levels of serum TPSA, AMH among Sudanese women with polycystic ovary syndrome and to determine the perfor...

Dissolution Kinetic and Solvent Extraction of Aluminium From Kaolin

  TABLE OF CONTENT Title page                                                                                                        i Certification                                                                                                    ii Dedication                 ...

Insilco Identification of Putative Drug Targets in Staphylococcus Aureus

ABSTRACT Staphylococcus aureus is one of the most important and studies gram-positive bacterial strains, which have a great potential to infect human being as well as other mammals. Staphylococcus aureus is a major cause of infections responsible for much life threatening diseases like toxic-shock syndrome, staphylococcal scarlet fever, meningitis, osteomyelitis etc. infection due to these strains are difficult to treat. This research work focused on the identification of drug target enzymes...

Serum Cystatin C And Creatinine As Markers Of Kidney Function In Adults In Enugu State, Nigeria

ABSTRACT With the increasing recognition of the several pitfalls of serum creatinine (SCr) and creatinine-based glomerular filtration rate (GFR) estimates as measures of kidney function, a novel biomarker, cystatin C (Cys C) which is claimed to be superior to the creatinine-based estimates has been proposed. However, this claim is yet to be validated in an indigenous black setting. This study was therefore, to verify this claim and to assess the best method to estimate GFR in a typical Afric...

Immunohistochemical Detection of Beta- Catenin in Ovarian Tumors Among Sudanese Women

This is hospital based analytical retrospective case control study was conducted at Soba university hospital, Omdurman military hospital, Omdurman maternity hospital (Khartoum state), and Sudan university of science and technology-college of medical laboratory science, during the period from September 2016 to February 2017. The study was aimed to detect beta-catenin expression in ovarian tumors, using immunohistochemistry. Forty paraffin block samples were collected from patients previo...

Detection of Plasminogen Activator Inhibitor-1 Gene Mutation 4G/5G among Deep Venous Thrombosis Sudanese Adult Patients in Khartoum State

A number of prothrombotic and fibrinolytic disorders may lead to venous thromboembolism(VTE). Venous thrombo embolism(VTE) includes deep vein thrombosis (DVT)and pulmonary embolism(PE).The disease is caused by many factors some of which are congenital and others are acquired. A 4G/5G polymorphism located in the promoter region of plasminogen activator inhibitor-1 (PAI-1) gene has been found to be commonly associated with the high levels of PAI-1 and might be a risk factor for deep vein...

Serum Magnesium Level And Related Biochemical Parameters in Cardiovascular Diseases at The Korle-Bu Teaching Hospital

ABSTRACT Background: Serum magnesium (Mg) and other biochemical abnormalities in cardiovascular diseases (CVD) is a global concern as it has been implicated in CVD related morbidity and mortality. However, results from studies of these biochemical abnormalities especially of serum magnesium in CVDs are conflicting and unclear with no data on CVD patients at the Korle-Bu Teaching Hospital; hence the focus of the current study. Aim: To determine serum magnesium and related biochemical paramete...

Serum Cytokine Profiles as Biomarker in Multi-Drug Resistant Tuberclosis

ABSTRACT Background: Tuberculosis (TB) remains a major threat to public health despite several efforts to curb the disease. Contributions made by TB control programs have been tremendous; however, the emergence of multi-drug resistant (MDR) tuberculosis is a big threat to the control efforts and calls for innovative measures to mitigate the effect. New TB control programs with a comprehensive approach to dealing with MDR-TB is needed globally. In particular, new nonsputum based diagnostic to...

PREVALENCE OF PFHRP2 AND/OR PFHRP3 GENE DELETIONS IN PLASMODIUM FALCIPARUM ISOLATES AND THE PERFORMANCE OF HRP2 BASED MALARIA RAPID DIAGNOSTIC TESTS

ABSTRACT BACKGROUND: Malaria rapid diagnostic tests (MRDTs) are important for malaria disease management. However, performance of the RDTs is affected when the targeted antigens in the parasite have a variation or are altogether absent. The most common parasite target antigen in RDTs, Plasmodium falciparum histidine-rich protein 2 (HRP2), has been reported to be absent in some P. falciparum parasites. Loss of the pfhrp2 in P. falciparum parasites affects the accuracy of PfHRP2 based RDT kits ...

Make nanotechnology research open-source

Despite being an extremely active area for academic research, publishing and patent applications, nanotechnology development is being hindered by current intellectual property (IP) law. Patenting of basic science and entire classes of nanotechnologies with overly broad claims is leading to higher transaction costs, slower and sub-optimal technical development and the removal of obvious knowledge from the public domain. This effectively hamstrings the current primal nanotechnology development,...

SIWES REPORT

 2018 ABSTRACT This technical report is based on what I have learned during my six months industrial training at Aminu Kano teaching hospital (AKTH). Chapter one is based on the Introduction of SIWES, objectives of SIWES, History and objectives of AKTH, functions of the available departments/units. Chapter three consists of relevant conclusions, experience gained and references.         TABLE OF CONTENTS Cover Page Title Page………………………………………………………...

CANCER OF THE LUNGS AND ITS PREVENTIONS

ABSTRACT Cancer of the lungs has been one of the main causes of death recently, and still is, Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. This growth can spread beyond the lung by the process of metastasis into nearby tissue or other parts of the body. Most cancers that start in the lung, known as primary lung cancers, are carcinomas. The two main types are small-cell lung carcinoma (SCLC) and non-small...

Laboratory Analysis and Pipeline Products Marketing Company (PPMC) Depot Operations

ABSTRACTThis research work was carried out to evaluate the laboratory analysis of pipeline products marketing company (PPMC) depot operations. In the course of the research many scholarly articles on the subject matter were reviewed from which the researcher got lot information concerning the topic at hand. Thus making the research work a reliable source of information as far as facts about petroleum products marketing company (PPMC) is concerned.The Pipeline Inspectorate is charged with the...

Products Contamination And Quality Control Analysis

SYNOPSIS Quality control can be seen as the activities that sustain the quality of a product in order to satisfy a given requirement or meet certain standards. (McGraw-Hill Dictionary, 2003). It is applicable in all phases of the production cycle. In food products, qualities such as composition, structure (molecular, microscopic and macroscopic), physicochemical and sensory attributes are all analyzed.  These analyses are carried out both to satisfy customers’ and meet regulatory stan...


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