Research Papers/Topics in Laboratory Technology

Causes of blood culture contamination at Nelson Mandela Academic Hospital

Phlebotomy has been practiced for centuries and is still one of the most common invasive procedures in health care. Each step in the process of phlebotomy affects the quality of the specimen and is thus important for preventing laboratory error, patient injury and even death. For example, the touch of a finger to verify the location of a vein before insertion of the needle increases the chances that a specimen will be contaminated. This causes false blood culture results, prolonged hospitaliz...

Serum Cystatin C And Creatinine As Markers Of Kidney Function In Adults In Enugu State, Nigeria

ABSTRACT With the increasing recognition of the several pitfalls of serum creatinine (SCr) and creatinine-based glomerular filtration rate (GFR) estimates as measures of kidney function, a novel biomarker, cystatin C (Cys C) which is claimed to be superior to the creatinine-based estimates has been proposed. However, this claim is yet to be validated in an indigenous black setting. This study was therefore, to verify this claim and to assess the best method to estimate GFR in a typical Afric...

Immunohistochemical Detection of Beta- Catenin in Ovarian Tumors Among Sudanese Women

This is hospital based analytical retrospective case control study was conducted at Soba university hospital, Omdurman military hospital, Omdurman maternity hospital (Khartoum state), and Sudan university of science and technology-college of medical laboratory science, during the period from September 2016 to February 2017. The study was aimed to detect beta-catenin expression in ovarian tumors, using immunohistochemistry. Forty paraffin block samples were collected from patients previo...

Detection of Plasminogen Activator Inhibitor-1 Gene Mutation 4G/5G among Deep Venous Thrombosis Sudanese Adult Patients in Khartoum State

A number of prothrombotic and fibrinolytic disorders may lead to venous thromboembolism(VTE). Venous thrombo embolism(VTE) includes deep vein thrombosis (DVT)and pulmonary embolism(PE).The disease is caused by many factors some of which are congenital and others are acquired. A 4G/5G polymorphism located in the promoter region of plasminogen activator inhibitor-1 (PAI-1) gene has been found to be commonly associated with the high levels of PAI-1 and might be a risk factor for deep vein...

Serum Magnesium Level And Related Biochemical Parameters in Cardiovascular Diseases at The Korle-Bu Teaching Hospital

ABSTRACT Background: Serum magnesium (Mg) and other biochemical abnormalities in cardiovascular diseases (CVD) is a global concern as it has been implicated in CVD related morbidity and mortality. However, results from studies of these biochemical abnormalities especially of serum magnesium in CVDs are conflicting and unclear with no data on CVD patients at the Korle-Bu Teaching Hospital; hence the focus of the current study. Aim: To determine serum magnesium and related biochemical paramete...