ABSTRACT Studies in a number of pilot Community Based Distribution (CBD) programmes have shown that CBD workers can deliver modern contraceptives and safe maternal and child health services (including treatment or management of common childhood diseases such as diarrhoea) in their communities (Weiss, 1985). CBD workers have been active in Akinyele Local Government Area (LGA) and a high number of diarrhoea episodes have been managed by them. Most efforts have been on the general assessment of ...
Abstract The teleost digestive tract is simple and comprises the following parts: oropharyngeal cavity, oesophagus, stomach, intestine, rectum and anus. These organs are involved in the breakdown of ingested food macromolecules into small absorbable micromolecules. These small molecules are necessary for the maintenance, growth and energy needs of the body (Johnson, 1994; Junqueira and Carneiro, 2005). Besides processing food, some parts of the tract have evolved into organs of respiration (p...
Abstract Background: Acetylated starches with degrees of substitution (DS) of > 2 have been found suitable for sustained release applications because of their hydrophobic nature and thermoplasticity. The short half-life and high dosing frequency of repaglinide make it an ideal candidate for sustained release. Objectives: To formulate and evaluate repaglinide microspheres using acetylated starch of the indigenous rice species Oryza glaberrima Steud (Ofada) as polymer. Materials and Methods: Of...
~bstretT. kp revaiurec ofh umah imrmmodt~ieirncyv irtlo ryp 1 d 2 in -1 arcas of Niiaia was estbled using 1089 ma colkacd in I8 kwhs &om 1992 to mrly 1 554. llx saa wmte sted with Enzyme linked Imm~enAtss ay @LISA) and cahntd by Westun hmrmob~BgE ehniquc. Overall, 13 (13%) of ibt 1089 &ra war positive for adi00 I W:I d m-2. Prwalenec of 0.6% md 0.8% wm obtained f& HIV-1 and HIY-2 mpcrhly. Tbc hjgk~ peevabo f HfV-1 and HTV-2 (50.Wh)w ere fdin Z uhlrma and Umubum A #mgmaleaet or 12%w as oblaiae...
ABSTRACT This work was designed to study the effects of Trypanosoma brucei and Trypanosoma congolense infection on the renal function of mongrel dogs. Also, the effects of treatment of the infection with diaminazene aceturate were evaluated. Sixteen (16) male mongrel dogs aged between 3 and 6 months, and weighing between 2.5 and 5.2 kg were used for the study. The dogs were acquired, numbered, tagged and weighed. The dogs were kept in clean metal cages in a fly proof house and were fed once ...
ABSTRACT This study was conducted to document the occurrence and characteristics of mycotic agents isolated from trade horses and donkeys in Obollo-Afor, Enugu State. A total of 497 horses and 65 donkeys presented for sale at Obollo-Afor horse/donkey market during the wet season (June to August 2014) and dry season (January to March 2015) were examined for skin lesions. For each horse/donkey examined, the location of skin lesion as well as the sex of the animal was recorded. Each skin lesion...
ABSTRACT The high turn-over rate and quest for white meat have given more impetus to poultry production. The need to increase production and meet the demand for poultry meat has necessitated the use of veterinary drugs, especially antimicrobials, for therapeutic, prophylactic and growth promotion purposes in poultry farming. These drugs tend to accumulate in tissues and organs as residues. The presence of drug residues in tissues above the maximum residue limit (MRL) becomes violative if wit...
ABSTRACT SUMMARY Objective: To determine patients' perceptions abou t the quality of care and possible factors that q'lay prevent adequate utilization of services at the study centre and therefore make recommendations for improvement in service utilization. Materials and methods: A cross sectional survey of patients from the Eye Clinic and Eye Ward of the University College Hospital. Ibadan, was carried out using a standardized questionnaire between May and June 2001. Results: A total of fi...
ABSTRACT Traditional Birth Attendants (TBAs) are lay persons who attend to deliveries and concerted efforts have been made to train them. Anecdotal reports suggest that many expectant mothers patronize TBAs in Ibadan. However, there is dearth of information relating to the TBAs’ maternal care knowledge and practices. This study was therefore conducted to assess TBAs’ knowledge and practices relating to maternal care in Ibadan, Oyo State. A cross-sectional survey of 407 out of 608 TBAs who...
ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 25...
Abstract Background: The World Health Organisation (WHO) guidelines for the control of malaria during pregnancy include prompt and effective case management of malaria combined with prevention of infection by insecticide-treated nets (ITNs) and intermittent preventive treatment in pregnancy (IPTp). Despite this the uptake is poor. Objective: To describe the malaria prevention measures utilized by these women in this environment. Methods: Information was obtained from consented pregnant and ne...
ABSTRACT Effect of stabilizing chloroquine phosphate in a synthetic Aluminium Magnesium silicate (Nanoparticles) on the antiplasmodial activity of the drug was investigated. Mice infected with Plasmodium berghei were treated with chloroquine phosphate at 7 mg/kg, 5 mg/kg and 3 mg/kg dose levels respectively. Two subgroups at each dose level were treated with chloroquine phosphate alone and with a drug formulation of 20% chloroquine phosphate in the synthetic Aluminium Magnesium Silicate (AMS...
ABSTRACT Controlled release floating metformin hydrochloride microbeads were prepared and optimized using a blend of varying concentrations of freeze-dried pregelatinized Chinese yam starch (Dioscorea oppositifolia L) and sodium alginate. Floating microbeads were prepared by the ionotropic gelation method using 10% w/v calcium chloride as the cross-linking agent and sodium bicarbonate as the gas releasing agent. A full 32 factorial design was used to investigate the influence of two variables...
ABSTRACT Diabetes mellitus is a group of metabolic disorders characterized by chronic hyperglycemic condition resulting from defects in insulin secretion, insulin action or both. It is a growing public health concern worldwide affecting humans and animals. Synthetic drugs available for the treatment of the ailment have serious side effects, complicated mode of intake and are costly. Literature search revealed that Cussonia arborea is used folklorically in the management of Diabetes mellitus....
ABSTRACT Fifteen dogs of similar age (8-12 months) were used for the clinical study. They were randomized into 3 groups (CH1-5, CL1-5 AND AC1-5). Simple transverse femoral fractures were created under anaesthesia using a bone saw. Spatial alignment of the bone was achieved by insertion of an intramedullary pin. Radiographic assessment confirmed that the pins were intact and internal fixation was thorough. Celecoxib (Celebrex® Pfizer Inc, Germany) was supplied in encapsulated powdered form a...