ABSTRACT Infectious diseases remain to be a global health burden due to the development of antibiotic resistance by pathogenic microorganisms. Antibiotic resistance has led to increased number of deaths among children and adults. This study sought to screen for antimicrobial activity of extracts from fungal endophytes against selected human pathogens, identify, and characterize the fungal endophytes and screen for phytochemicals present in selected medicinal plants‟ extracts. Sixty-five fu...
ABSTRACT Soybean is afected by a wide range of diseases, many of which are seed-borne. Infection by seed-borne pathogens leads to seed rot, low seedling vigour and reduction in plant growth. Seed-borne fungal pathogens on farmer-saved seeds of soybeans were investigated by examining a total of eleven (11) seed samples from two districts (Saboba and Yendi) in the Northern region and one from CSIR-Savanna Agricultural Research Institute (CSIR-SARI). Appearance quality of farmer-saved soybean se...
ABSTRACT Background Buruli ulcer (BU) is a skin disease caused by Mycobacterium ulcerans. BU is the third most common mycobacterial disease after tuberculosis and leprosy, but in Ghana and Cote d’ Ivoire, it is the second. M. ulcerans produces mycolactone, an immunosuppressant macrolide toxin which makes the infection painless. However, some patients have complained of painful lesions and delay healing. Painful ulcers and delay healing experienced by some patients may be due to secondary ba...
ABSTRACT Cultivation of Jatropha curcas L. for production of biodiesel as an alternative source of energy is crucial for sustainable development in Nigeria. Pests and pathogens especially fungi have been reported to be a major constraint to commercial cultivation of J. curcas in Asia and some West African countries. However, this is yet to be fully investigated and documented in Nigeria. Fungal pathogens infecting J. curcas in southwestern Nigeria were therefore investigated. Two hundred plan...
ABSTRACT Background: Hepatitis B virus and HIV infections are endemic in sub-Saharan Africa where 22.9 million individuals are estimated to be infected with HIV and nearly 50 million people are chronic HBV carriers. Due to similar routes of transmission, co-infections with the two viruses are common. Hepatitis B being severely infectious and found in HIV-positive patients, could pose more serious health problems. In Ghana, the prevalence of HBV infection is estimated at 15% of the adult popul...
Abstract: Entomopathogenic fungi have been explored as a potential biopesticide to counteract the insecticide resistance issue in mosquitoes. However, little is known about the possibility that genetic resistance to fungal biopesticides could evolve in mosquito populations. Here, we detected an important genetic component underlying Anopheles coluzzii survival after exposure to the entomopathogenic fungus Metarhizium anisopliae. A familiality study detected variation for survival among wild ...
ABSTRACT Giardiasis and cryptosporidiosis remain as part of the commonest gastroenteritis in Ghana. The diseases are caused by the protozoan parasites, Giardia lamblia and Cryptosporidium sp. respectively. Inadequate supply of treated water and poor sanitation are some of the key factors leading to the spread of these infections. Being zoonotic diseases, it is suspected that, a large proportion of human infections could come from infected domestic and farm animals. Though, use of molecular to...
Cultivation of Jatropha curcas L. for production of biodiesel as an alternative source of energy is crucial for sustainable development in Nigeria. Pests and pathogens especially fungi have been reported to be a major constraint to commercial cultivation of J. curcas in Asia and some West African countries. However, this is yet to be fully investigated and documented in Nigeria. Fungal pathogens infecting J. curcas in southwestern Nigeria were therefore investigated. Two hundred plant s...
ABSTRACT Understanding the interrelationships between injury, infection and diversity of Theileria in a zebra population may illuminate the mechanisms by which injuries influence the course of latent infections, and may be an important factor to be considered during therapy of injured animals. Currently, the molecular diversity of Theileria species that are circulating in Kenyan free living common zebras is unknown and the effect of anthropogenic induced injuries on Theileria diversity and in...
ABSTRACT Intestinal parasite co-infections are major public health problems of children in developing countries causing under nutrition, anaemia obstruction, mental and physical growth retardation. This study was conducted to assess the prevalence of soil transmitted helminth (STHs) and malaria co-infection among primary school children in Ogba/Egbema/Ndoni Local Government Area, Rivers state Nigeria. A total of 464 stools were sampled randomly from three Egbema community primary school c...
Background: Type 2 diabetes comes with various complications and this may be compounded by morbidities of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Aims: This study examined the prevalence of HBV and HCV infectionst among type 2 diabetics as well as its associated factors. This randomized crossâsectional study was conducted at the Diabetic Clinic of the Central Regional Hospital, Cape Coast between December 2012 and April 2013. Subjects and Methods: A wellâstructured q...
Abstract: Maize lethal necrosis (MLN) is a virus disease complex that was recently reported in eastern Africa. It causes huge yield losses, hence threatening food security in the region. It is caused by a co-infection of Maize chlorotic mottle virus (MCMV) and Sugarcane mosaic virus (SCMV) in maize and other cereal crops. Thrips and beetles are known vectors of MCMV while SCMV is vectored by aphids. Since MLN is new to Africa, there are no known effective management strategies against the di...
ABSTRACT ;/ descript ive cross -, section analysis 0/ five hundred patients who were symptomatically diagnosed of malaria in three locations: Saki (peri-urban), Ibadan (urban) and Lagos (highly urbanized) were recruited /01' this study using a well structured questionnaire between September 2005 and June 2006. The prevalence 0/ both malaria and HIV infections were higher in Peri-Urban town than the other two locations. We observed that 80% were HIV positive in Saki. 20% in Ibadan and 37. J % ...
ABSTRACT Background: Injecting drug use has created a major international public health problem where on average 6 million people are injecting drugs worldwide. This study aimed to explore the potential of bridging the HIV infection from injection drug users (IDUs) through sexual networks to the general population in Zanzibar. Seek to understand the interplay between injection drug use, sexual behavior and the epidemiological shift in the transmission of HIV infection between key population ...
Abstract: Malaria remains among the world’s deadliest diseases, and control efforts depend critically on the availability of effective diagnostic tools, particularly for the identification of asymptomatic infections, which play a key role in disease persistence and may account for most instances of transmission but often evade detection by current screening methods. Research on humans and in animal models has shown that infection by malaria parasites elicits changes in host odors that infl...