Diabetes mellitus, also known as diabetes has on major effect on its patients. This is the
effect of impaired wound healing. Patients thus get minor wounds such as small cuts which
become non-healing and are liable to get infected. Severe cases of such occasions lead to
amputations. A solution to this problem is tissue regeneration with the help of scaffolds. These
scaffolds are made of biopolymers and promote cell adhesion, regeneration and minimal
Computer Aided Design (CAD) software (SolidWorks), was used to design models of
scaffolds. Three dimensional (3D) scaffolds were then 3D printed. Scaffolds were also casted
using PLA and a mixture of PLA and PEG. The models along with its samples undergo tensile,
stiffness and mass degradation tests to gain insight on whether this model is applicable.
Computer simulations were used to evaluate the tensile properties under real world
conditions. Furthermore, a universal testing machine was then used to validate the properties
obtained from the computer simulations. There was no significant difference in the methods.
Optical properties were characterised with USB poroscope imaging microscope to show that
3D printing produces much more uniform distribution of pores. Mass loss experiments were
also conducted to determine mechanical stability at different pH. It was noticed that the samples
degrade faster when in an acidic environment.
CDR, C (2021). Fabrication of 3D Printed Scaffolds for Tissue Engineering: Understanding the Mechanical Stability, Degradation Mechanisms and Biocompatibility.. Afribary.com: Retrieved April 10, 2021, from https://afribary.com/works/fabrication-of-3d-printed-scaffolds-for-tissue-engineering-understanding-the-mechanical-stability-degradation-mechanisms-and-biocompatibility
Coalition, CDR. "Fabrication of 3D Printed Scaffolds for Tissue Engineering: Understanding the Mechanical Stability, Degradation Mechanisms and Biocompatibility." Afribary.com. Afribary.com, 02 Apr. 2021, https://afribary.com/works/fabrication-of-3d-printed-scaffolds-for-tissue-engineering-understanding-the-mechanical-stability-degradation-mechanisms-and-biocompatibility . Accessed 10 Apr. 2021.
Coalition, CDR. "Fabrication of 3D Printed Scaffolds for Tissue Engineering: Understanding the Mechanical Stability, Degradation Mechanisms and Biocompatibility.". Afribary.com, Afribary.com, 02 Apr. 2021. Web. 10 Apr. 2021. < https://afribary.com/works/fabrication-of-3d-printed-scaffolds-for-tissue-engineering-understanding-the-mechanical-stability-degradation-mechanisms-and-biocompatibility >.
Coalition, CDR. "Fabrication of 3D Printed Scaffolds for Tissue Engineering: Understanding the Mechanical Stability, Degradation Mechanisms and Biocompatibility." Afribary.com (2021). Accessed April 10, 2021. https://afribary.com/works/fabrication-of-3d-printed-scaffolds-for-tissue-engineering-understanding-the-mechanical-stability-degradation-mechanisms-and-biocompatibility