A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata

Abstract

A new 3,8′′-flavanone-flavonol dimer gnidiflavanone-flavonol (1) and 10 known compounds (2–11), including four rare primula-type flavones 2–5, were isolated from the roots of Gnidia apiculata. Compounds 2–5 and 7 were reported for the first time from the plant family Thymelaeceae. Structures of the isolated compounds were established by spectroscopic data, including 1D and 2D NMR (COSY, HMBC, HSQC and ROESY) and mass spectrometry, as well as by the comparison with literature data. The crude roots extract and isolated compounds were evaluated for antimicrobial and antiplasmodial activities. Among isolated compounds, 6-hydroxyflavone (4) and 6-O-acetylflavone (4a) showed antiplasmodial activity against chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum.

Report Access / View File

Overall Rating

0

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

APA

W., K (2024). A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata. Afribary. Retrieved from https://afribary.com/works/a-new-gnidiflavanone-flavonol-dimer-and-other-constituents-from-gnidia-apiculata

MLA 8th

W., Kamau "A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata" Afribary. Afribary, 04 Jun. 2024, https://afribary.com/works/a-new-gnidiflavanone-flavonol-dimer-and-other-constituents-from-gnidia-apiculata. Accessed 21 Dec. 2024.

MLA7

W., Kamau . "A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata". Afribary, Afribary, 04 Jun. 2024. Web. 21 Dec. 2024. < https://afribary.com/works/a-new-gnidiflavanone-flavonol-dimer-and-other-constituents-from-gnidia-apiculata >.

Chicago

W., Kamau . "A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata" Afribary (2024). Accessed December 21, 2024. https://afribary.com/works/a-new-gnidiflavanone-flavonol-dimer-and-other-constituents-from-gnidia-apiculata

A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata

0

Document Details

Related Works