ABSTRACT
Human fungal infections pose serious medical issues. Up to now, more than a hundred
thousand fungal species are considered as natural contaminants. During the last decade,
the incidence of superficial and deep mycotic infections has continued to increase
explosively. There is a general consensus among researchers, clinicians and
pharmaceutical companies that new, potent, effective and safe antifungal drugs are
needed. Majority of work has been conducted on Camellia sinensis extracts against
bacterial agent’s activity but little work for antifungal activity. In this study, in vitro
antifungal activities of Camellia sinensis crude extracts compared with azole group of
compounds on selected pathogenic and mycotoxic fungi were determined. That was done
by evaluating the difference in antifungal activities of green and black tea crude extracts
having a concentration of 100mg mL-1. Quantitative bioassay was done using disc
diffusion method and Minimum Inhibition Concentration was done using broth dilution
methods. The fungal isolates used for bioactivity testing were yeasts; Candida famata, C.
lusitaniae, C. tropicalis ATCC 750, C. parapsilosis ATCC 22019, C. glabrata ATCC
24433, C. krusei ATCC 6258 and Cryptococcus neoformans ATCC 66031; and moulds,
Trichophyton mentagrophytes, Microsporum gypseum, Fusarium monilliforme,
Aspergillus spp and Penicillium chrysogeneum. ATCC standard fungal strains and
clinical isolates were included. Green tea crude extract showed stronger inhibitory effect
against the fungal strains tested than black tea crude extract. There was a significant
difference in zone of inhibitions (T=4.09, P
CHERUIYOT, E (2021). Antifungal Activities Of Camellia Sinensis Crude Extract On Selected Pathogenic And Mycotoxic Fungi. Afribary. Retrieved from https://afribary.com/works/antifungal-activities-of-camellia-sinensis-crude-extract-on-selected-pathogenic-and-mycotoxic-fungi
CHERUIYOT, EROLLS "Antifungal Activities Of Camellia Sinensis Crude Extract On Selected Pathogenic And Mycotoxic Fungi" Afribary. Afribary, 01 Jun. 2021, https://afribary.com/works/antifungal-activities-of-camellia-sinensis-crude-extract-on-selected-pathogenic-and-mycotoxic-fungi. Accessed 22 Dec. 2024.
CHERUIYOT, EROLLS . "Antifungal Activities Of Camellia Sinensis Crude Extract On Selected Pathogenic And Mycotoxic Fungi". Afribary, Afribary, 01 Jun. 2021. Web. 22 Dec. 2024. < https://afribary.com/works/antifungal-activities-of-camellia-sinensis-crude-extract-on-selected-pathogenic-and-mycotoxic-fungi >.
CHERUIYOT, EROLLS . "Antifungal Activities Of Camellia Sinensis Crude Extract On Selected Pathogenic And Mycotoxic Fungi" Afribary (2021). Accessed December 22, 2024. https://afribary.com/works/antifungal-activities-of-camellia-sinensis-crude-extract-on-selected-pathogenic-and-mycotoxic-fungi