Typhoid fever is a waterborne and foodborne disease caused by Salmonella enterica serotype Typhi (S. Typhi). Studies have established that some patients presenting with typhoid-like symptoms are usually inflicted by other bacteria pathogens, which may or may not be transmitted by fecal oral route. It is common belief that typhoid fever cases are high in Alupe and continue to cause significant morbidity among the people of Alupe, Busia County. The study focused on isolation and characterization of the bacteria pathogens in blood and stool among patients presenting with typhoid fever symptoms at two health facilities located in Alupe, Busia County. A total of one hundred and fifty patients were recruited and thereafter their blood and stool samples collected. Subsequently, laboratory analysis at KEMRI-CIPDCR was done to isolate and characterize bacteria pathogens as well as their antibiotic susceptibility profiles done. One hundred and forty nine blood cultures and 140 stool cultures were performed. Bacterial pathogens were detected in 11 positive cultures with both gram-positive (27.3%) and gram-negative bacteria (72.7%) obtained. Bacteria isolated from blood cultures included Staphylococcus aureus (50%), Proteus mirabilis (16.67%) and Escherichia coli (33.33%). Those from stool cultures included Escherichia coli (80%) and Shigella dysentriae (20%). Using Widal test, 73 (50%) samples tested positive for typhoid but there was no S. Typhi isolated from both blood and stool cultures. All the isolates showed moderate to high resistance to ampicillin-cloxacillin, tetracycline and cefuroxime.
WANJIRU, M (2021). Isolation And Characterization Of Bacteria Pathogens In Blood And Stool Samples Among Patients Presenting With Typhoid Fever Symptoms In Alupe, Busia County. Afribary. Retrieved from https://afribary.com/works/isolation-and-characterization-of-bacteria-pathogens-in-blood-and-stool-samples-among-patients-presenting-with-typhoid-fever-symptoms-in-alupe-busia-county
WANJIRU, MUREITHI "Isolation And Characterization Of Bacteria Pathogens In Blood And Stool Samples Among Patients Presenting With Typhoid Fever Symptoms In Alupe, Busia County" Afribary. Afribary, 03 Jun. 2021, https://afribary.com/works/isolation-and-characterization-of-bacteria-pathogens-in-blood-and-stool-samples-among-patients-presenting-with-typhoid-fever-symptoms-in-alupe-busia-county. Accessed 19 Apr. 2024.
WANJIRU, MUREITHI . "Isolation And Characterization Of Bacteria Pathogens In Blood And Stool Samples Among Patients Presenting With Typhoid Fever Symptoms In Alupe, Busia County". Afribary, Afribary, 03 Jun. 2021. Web. 19 Apr. 2024. < https://afribary.com/works/isolation-and-characterization-of-bacteria-pathogens-in-blood-and-stool-samples-among-patients-presenting-with-typhoid-fever-symptoms-in-alupe-busia-county >.
WANJIRU, MUREITHI . "Isolation And Characterization Of Bacteria Pathogens In Blood And Stool Samples Among Patients Presenting With Typhoid Fever Symptoms In Alupe, Busia County" Afribary (2021). Accessed April 19, 2024. https://afribary.com/works/isolation-and-characterization-of-bacteria-pathogens-in-blood-and-stool-samples-among-patients-presenting-with-typhoid-fever-symptoms-in-alupe-busia-county