Potential of adverse effects due to aluminium, barium and strontium in GIC [November 19, 2016]

Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from glassionomer cements (GICs) were found.

Clinical outcomes: A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to have a measurable effect. This, in turn, suggests that there are unlikely to be any adverse health effects arising from the presence of these fillings.The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]