Potential of adverse effects due to aluminium, barium and strontium in GIC

Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from GICs were found. A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to have a measurable effect. This, in turn, suggests that there are unlikely to be any adverse health effects arising from the presence of these fillings.

Clinical outcomes: None

State of evidence and recommendations: The quality of the existing evidence requires further assessment.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]