What effect has CPP-ACP on the plaque pH? [November 16, 2016]

Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo.

Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]