A NOVEL COMBINATORIAL DESIGN STRATEGY FOR BIOMEDICAL TIBASED ALLOYS

Titanium alloys with benign elements including Nb, Mo, Ta, and Zr are promising
biomedical materials owing to their corrosion resistance, biocompatibility, high strength,
toughness, and wear resistance. However, stress shielding has limited their use. When soft
bone tissue (E=20-40GPa) is replaced with a stiffer implant, the implant guards the
surrounding skeleton. Lessening bone loads causes resorption, which reduces bone density,
mineralization, and strength. Stress shielding may cause joint loosening, implant failure, or
fragment-caused infections. For this reason, our research aims to create a novel biomaterial
for load transfer implants. An ab initio theoretical computation was utilised to relate elastic
characteristics from homogenised multiphase elastic parameters for designing novel Ti-MoNb-Zr alloys with bone matching modulus. The consistency between forecasts and extensive
experimental characterization throws insight on the multi-phase feature of polycrystalline
composites' structural and mechanical properties. The impact of heat treatment and cold
work on alloy modulus is also discussed. The work reveals that the unique combinatorial
technique may be particularly advantageous for decreasing the Young's modulus of metallic
biomaterials, which prevents stress shielding and bone resorption in orthopaedic implants.