Abstract: Atherogenic cardiovascular risk assessment is important in the
management of dyslipidaemia associated with antiretroviral therapy (ART).
Generally, Castelli‟s Risk Index (CRI), Atherogenic Index of Plasma (AIP) and
Atherogenic coefficient (AC) are becoming useful indices as risk predictors for
cardiovascular disease (CVD). We studied the importance of these indices in
identifying at-risk HIV individuals receiving treatment. Eighty (80) HIV-patients
comprising treatment (n=40) and treatment-naïve (n=40) groups with age- and sexmatched
were enrolled. Traditional lipid parameters {Total cholesterol (TC),
Triglycerol (TG), and HDLc} were analyzed using spectrophotometry. The LDLc
was calculated using Friedewald equation. Non-HDLc, CRI-I (TC/HDLc ratio) and
CRI-II (LDLc/HDLc ratio), AIP {Log10 (TG/HDL-c)} and AC {(Non-
HDLc)/HDLc} were also calculated. The CD4+ cell count was determined using
flow cytometry. The correlations between atherogenic indices and lipid profile
were determined using Pearson‟s correlation. P < 0.05 was considered as
significant. Risk estimation by stratification based on number of altered lipid
profile parameter showed no significant increase (P>0.05) in any of the traditional
lipid profile parameters except for HDLc with significant elevation (P
Kamoru Ademola, A. & Japhet;, O (2018). Castelli Risk Index, Atherogenic Index of Plasma, and Atherogenic Coefficient: Emerging Risk Predictors of Cardiovascular Disease in HIV-Treated Patients. Afribary. Retrieved from https://afribary.com/works/castelli-risk-index-atherogenic-index-of-plasma-and-atherogenic-coefficient-emerging-risk-predictors-of-cardiovascular-disease-in-hiv-treated-patients
Kamoru Ademola, Adedokun, and Olisekodiaka Japhet; "Castelli Risk Index, Atherogenic Index of Plasma, and Atherogenic Coefficient: Emerging Risk Predictors of Cardiovascular Disease in HIV-Treated Patients" Afribary. Afribary, 26 Mar. 2018, https://afribary.com/works/castelli-risk-index-atherogenic-index-of-plasma-and-atherogenic-coefficient-emerging-risk-predictors-of-cardiovascular-disease-in-hiv-treated-patients. Accessed 24 Apr. 2024.
Kamoru Ademola, Adedokun, and Olisekodiaka Japhet; . "Castelli Risk Index, Atherogenic Index of Plasma, and Atherogenic Coefficient: Emerging Risk Predictors of Cardiovascular Disease in HIV-Treated Patients". Afribary, Afribary, 26 Mar. 2018. Web. 24 Apr. 2024. < https://afribary.com/works/castelli-risk-index-atherogenic-index-of-plasma-and-atherogenic-coefficient-emerging-risk-predictors-of-cardiovascular-disease-in-hiv-treated-patients >.
Kamoru Ademola, Adedokun and Japhet;, Olisekodiaka . "Castelli Risk Index, Atherogenic Index of Plasma, and Atherogenic Coefficient: Emerging Risk Predictors of Cardiovascular Disease in HIV-Treated Patients" Afribary (2018). Accessed April 24, 2024. https://afribary.com/works/castelli-risk-index-atherogenic-index-of-plasma-and-atherogenic-coefficient-emerging-risk-predictors-of-cardiovascular-disease-in-hiv-treated-patients