Abstract
The compressional characteristics and tableting properties of starches from four
yam species namely Dioscorea dumetorum Pax (Bitter); Dioscorea oppositifolia L
(Chinese); Dioscorea alata L.DIAL2 (Water) and Dioscorea rotundata Poir (White) were
investigated in comparison with corn starch. The physicochemical properties of the starches
were evaluated using established methods while the compressional characteristics were
analyzed using density measurements, and the Heckel and Kawakita equations. The
properties of the tablets were assessed using Tensile strength (T), Brittle Fracture Index
(BFI), Friability (F) and Disintegration Time (DT). The physicochemical properties of the
starches varied considerably among the various species. The ranking for the mean yield
pressure (Py) obtained from Heckel plots was Chinese > Bitter>Corn > White>Water while
the ranking was the reverse for another pressure term, Pk, obtained from Kawakita plots.
The ranking for T was Chinese > Bitter>Corn > White>Water. The T values were inversely
related to Pk values. The ranking of DT was Bitter>Chinese>Corn>White> Water, while the
ranking was reverse for BFI and F. Water and White yam starch tablets did not conform to
the Pharmacopoeia requirements on friability (≤1%) while all the starch tablets except
Bitter yam starch conformed to the requirements on disintegration (≤ 15minutes). Thus, the
starches could be useful as excipients in tablet formulations.
Coalition, C., OKUNLOLA, A & ODEKU, O (2021). COMPRESSIONAL CHARACTERISTICS AND TABLETING PROPERTIES OF STARCHES OBTAINED FROM FOUR DIOSCOREA SPECIES. Afribary. Retrieved from https://afribary.com/works/compressional-characteristics-and-tableting-properties-of-starches-obtained-from-four-dioscorea-species
Coalition, CDR, et. al. "COMPRESSIONAL CHARACTERISTICS AND TABLETING PROPERTIES OF STARCHES OBTAINED FROM FOUR DIOSCOREA SPECIES" Afribary. Afribary, 03 Apr. 2021, https://afribary.com/works/compressional-characteristics-and-tableting-properties-of-starches-obtained-from-four-dioscorea-species. Accessed 24 May. 2022.
Coalition, CDR, ADENIKE OKUNLOLA and OLUWATOYIN ODEKU . "COMPRESSIONAL CHARACTERISTICS AND TABLETING PROPERTIES OF STARCHES OBTAINED FROM FOUR DIOSCOREA SPECIES". Afribary, Afribary, 03 Apr. 2021. Web. 24 May. 2022. < https://afribary.com/works/compressional-characteristics-and-tableting-properties-of-starches-obtained-from-four-dioscorea-species >.
Coalition, CDR, ADENIKE OKUNLOLA and OLUWATOYIN ODEKU . "COMPRESSIONAL CHARACTERISTICS AND TABLETING PROPERTIES OF STARCHES OBTAINED FROM FOUR DIOSCOREA SPECIES" Afribary (2021). Accessed May 24, 2022. https://afribary.com/works/compressional-characteristics-and-tableting-properties-of-starches-obtained-from-four-dioscorea-species