ABSTRACTThe indiscriminate use of antibiotics has become a global problem with implications for effective therapy of infections and dose resistance. The objective of this study is to determine the profile of antibiotic use at the Regional Hospital Buea. The data used for this study was obtained using a Checklist and the data obtained were analysed with the aid of Statistical Package for the Social Sciences and presented in a percentage table. In this study females were higher 83(55.3%), whic...
AbstractThe purpose of the study was to investigate the hypoglycemic effects of ethanolic and hexane extracts of Sonchus oleraceus in normal albino rats using fasting blood glucose and glucose tolerance tests. About 200 g leaves of S. oleraceus were macerated in 2 liters of hexane for two days, filtered and evaporated to dryness. Sixty albino rats were divided into six groups. Negative control group received water (5ml) and the positive control group administered by glibenclamide (5 mg/...
ABSTRACTBackground: Irrational use of medicines is a maJor problem worldwide. Studiesconducted in several countries, including Uganda, indicate that more than 50% of allmedicines used globally are used irrationally. Irrational use of medicines results inincreased risk of adverse reactions, wastage of the scarce resources, and development ofpreventable resistance of organisms to commonly used antibiotics. To be able designappropriate interventions, there is need to carry out drug use stu...
ABSTRACT. Prevention of irrational use of medicines may reduce healthcare costs and potentially save I ives. In line with World Health Organization (WHO) recommendation, a retrospective, cross-sectional descriptive study was carried out to obtain information on prescribing in the general outpatient department of Kampala International University Teaching Hospital in Ishaka-Bushenyi, Uganda. A sample of 884 prescriptions was selected by systematic random sampling using an interval of ...
ABSTRACTBackground: Lidocaine, is an important anesthetic and anti-arrhythmic drug, widely used in medicine,at the same time a danger. The impurity 2, 6-xylidine is the starting material for its manufacture,degradation product of lidocaine on storage and metabolite when administered. This study seeks toidentify 3 brands of lidocaine in Uganda Pharmacies, assess level of impurity and drug content by acomparative pharmacopoeial chemical analysis.Aim: To do a comparative pharmacopoeial ana...
ABSTRACT Introduction: It has been reported that the main factors behind the emergence of drug resistance is the use and misuse of antimicrobial drugs during the past few decades, but there is also the aspect of epidemic spread of drug-resistant bacteria as a factor. This has caused a major concern with serious implications in human and animal health. It's noted that as much as man's action contribute to the development of antimicrobial drug resistance, it is also seen with domestic ...
ABSTRACTOcimum gratissimum and Ocimum suave belong to the family lamiaceae. Folkore medicineclaims their use in many conditions.Leaves of 0 gratissimum and 0 suave were extracted in aqueous methanol by maceration,extract was filtered and evaporated using the rotary evaporator and dried to a constant weight inan oven. Phytochemical analysis was carried out to determine the active constituents andQuantification tests were carried out to obtain the amount of phytochmicals in each extract....
ABSTRACTThis study was done to evaluate the physicochemical properties, quality control parameters andthe dissolution profiles of circulating samples of artemether/lumefantrine sold at Pharmacies inKampala. The physicochemical parameters and assay of thirteen ( 13) brands of the productswere assessed through the evaluation of uniformity of tablet weight, friability test, disintegrationtest and assay of active pharmaceutical ingredients according to established methods.The dissolution rat...
ABSTRACT.The purpose of this study was to evaluate the antibacterial activity, to determine the mostefficiency extractive solvents and phytochemical profile of Hot water, Methanol alcohol andLemon juice extract of Lawsonia inermis (henna) leaf.The plant attracted the attention of researchers because of its use as anti-infective agent.The oily and alcoholic extracts of the plant Lawsonia inermis dried powdered leaves wereseparately obtained by maceration, while the aqueous was obtained b...
Quality Assurance System Assessment In Bushenyi District Health Facilities
ABSTRACTThe Ugandan government has experimented with various supply chain models for delivery ofessential drugs and supplies. In 20 I 0, the dual pull-push system was adopted; however drug stockouts are still a common occurrence in health facilities.This study on availability of essential medicines during the dual Pull-Push system in Kaliro Districtwas undertaken; this was to be used as an indirect or direct indicator of availability of essentialdrugs and medical supplies during the dua...
ABSTRACT The objective of this research was to investigate the anti-hyperglyceamic properties of the aqueous extract green peel of (Banana) musa acuminata 'nakitembe cultivar' in alloxan induced diabetic rats. The extract used was obtaned from the green banana dried and phytochemical analysis and acute toxicity study carried out. Alloxan was used to induce diabetes in experimental albino Rats at a dose of 140mg/kg body weight. After three days, the animals blood sugar levels was tested ...
ABSTRACTBackgroundDespite the fact that herbal medicines are used by 80% of the World's population (WHO, 2002)and are the main source of health care in the rural communities and the most preferred form oftreatment of HIV-related symptoms (Orisatoki and Oguntibeju, 20 I 0), less than I 0% of herbalproducts in the world market are tru ly standardized to a known active and/or toxic components(Winston et al. , 2007). Study carried out in Western Uganda reported 32.8% of same-day use ofherbal med...
ABSTRACT.Irrational prescribing of ARVs to HfV pregnant women is a major problem of poor controlof HIV/AIDS all over the world. The researcher assessed the rational prescribing ofARVs and identified factors which contribute to poor prescribing skills and adherence tothe National guidelines.A retrospective cross sectional approach was used in studying a sample of pregnantHIV women attending different health institutions in Bushenyi District as from 1stJanuary 2008 to 31 st December 2009.T...
ABSTRACTThe history of use of herbal medicine dates back to more than 4000 years. A wide range of plantshave been utilized for treatment of multiple disorders of the liver. The utilization has been asextracts of single plants and also compound preparations of more than one-plant type. Herbalmedicine has been categorically employed for a variety of medical problems and modern trendshave helped in extracting the active ingredients which have been classed into many chemicalgroups such as al...