Research Papers/Topics in Pharmacy

Insulins: Analogues, Structure - Activity Relationship, Administration, Case Study, and Outcomes Studies

The seminar presentation delves into the evaluation of various Insulin analogues, structural modifications in relation to clinical response, cost-effectiveness and pharmacoeconomics especially with indigwnt patients and complex patients with co-morbidities that will be on it for a long time, and its value as well. This was presented at the University College Hospital Ibadan, Nigeria.

Hepatitis B/ Hepatitis C/ Decompensated Hepatic Disease/ Cirrhotic Disease of the Liver

This is a compilation of the slides presented at the University College Hospital Ibadan, Nigeria, which entails the literature review, epidemiology, case study on Hepatitis and associated disease conditions. This also explains the significance of Pharmacists in improving adherence to therapeutic regimens, understanding of the risk factors and various predispositions to liver diseases, the cost-effectiveness, cost-benefits analysis, and the medication therapy management in the assessment of He...

NON-HODGKIN LYMPHOMA

This is a compilation of the slides presented at the University College Hospital Ibadan, Nigeria, which entails the literature review, epidemiology, case study on Non-Hodgkin Lymphoma. This also explains the significance of Pharmacists in the cost-effectiveness, cost-benefits analysis, and the medication therapy management in the assessment of Non-Hodgkin Lymphoma 

Development of Lipid-Based Microsuspensions for Ophthalmic Delivery of Gentamicin

ABSTRACT The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human eye, extending contact time of drug with the cornea, increasing the penetration through the complex anatomical structure of the ey...

Evaluation of Anti-Ulcer Properties of Methanol Extract of Terminalia Superba Engl. & Diels (Combretaceae) Stem Bark

ABSTRACT Terminalia superba Engl. & Diels (Combretaceae), is a member of the genus Terminalia that comprises around 100 species distributed in tropical regions of the world. In Africa it is found along the coast of west and central Africa. It has different uses in traditional medicine such as antimalarial, anti-diabetic, anti-fungal, and anti-hypertensive in the areas where it is found. Most of these uses are yet to be scientifically investigated. The powdered stem bark of Terminalia superba ...

Physicochemical Study of the Interaction of Some Water Soluble Vitamins with Veegum

ABSTRACT. The interact ion of some water soluble vitamins -thiamine hydrochloride, riboflavin, nicotinarnide, pyridoxine hydrochloride and ascorbic acid with a xmntnlorillonite clay (Vecgum) has been investigated. The data obtained from the interactive studies fitted well on the isothermal equilibrium adsorption-tikc plots. Th3 results were analyzed using the Langmuir's equatim The Langmuirs p!3t yiclded reasonable linearity fiom which interactive constmts were ca!cc!atx!. The theoretical max...

Production, Characterization and Application of Multiple Modified Maize Starches in the Formulation of Oral Solid Dosage Forms of Gentamicin Sulphate

ABSTRACT Modified and unmodified starches in current use have limited applications in pharmaceutical industries. Extending the modification beyond the existing level may increase their applicability in dosage forms design especially for gentamicin sulphate, a difficult to formulate broad spectrum antibiotic for oral administration. In this research, maize starch was chemically modified to three levels (primary, secondary and tertiary) using pre-determined optimal conditions and established mo...

Formulation and Optimization of Artemether and Lumefantrine Calcium Alginate Capsules Using Inverse Gelation Technique

ABSTRACT Poorly water-soluble drug candidates are associated with dissolution, absorption and bioavailability challenges. Consequently, poor solubility and non-reproducible absorption from the gastrointestinal tract following oral administration constitute a biopharmaceutical concern to dosage form design and formulation. The use of lipid-based formulations to address this concern has been the choice of many scientists in the drug delivery domain. Artemether and Lumefantrine the drugs investi...

Determination of Antibacterial Activity of Whole Plant Extract of Phyllantltus Amarus Schum and Thonn (Kabamba Maliba) against Shigella Dysenteriae.

TABLE OF CONTENTS DECLARATION ............................................................................................................................ i DEDICATION ............................................................................................................................... ii APPROVAL ................................................................................................................................. iii ACKNOWLEDGMENT ...........................................

Assessment of Knowledge On Use of Artemether Lumefantrine in Management of Uncomplicated Malaria Among Outpatients at Klu-Th

ABSTRACT This study sought to assess the knowledge on the use of Artemether/ therapy in the management of uncomplicated malaria among out patients treated at KlU-TH. A cross sectional study design was employed in this study. Data was collected from August to October 2018 using a questionnaire by simple Random sampling and was entered and analyzed using Microsoft Excel spread sheet and Statistical Package of Social Sciences (SPSS) version 20 respectively. The results were presented in form of ...

Pharmaco-Economic Analysis of Brands of Antacid Formulations Available in Ishaka Town Using Titrimetric Method

ABSTRACT Pharmaco-economics involves comparing the cost and consequences of products and services and Cost-effectiveness is the relationship between cost and effectiveness of a given drug. ANC of an antacid is one of the ways of evaluating effectiveness of antacid brands. ANC (mEq per unit dose) is the ability of the antacid to neutralize gastric acid (Shery et al., 2013), and it should be greater or equal to 5mEq per unit dose(FDA), where a unit dose of 0.5g for tablets and 5ml for suspensio...

Comparative Pharmacopoeia Analysis of Selected Brands of Diclofenac Sodium Tablets Available in Western Uganda Pharmacies based On Bp 2009

ABSTRACT Jackground: Diclofenac is one of the most commonly used non-steroidal anti-inflammatory lrugs (NSAIDs) for the treatment of pain, rheumatism and other inflammatory conditions.Aim: ~his study aimed to investigate whether the selected brands of diclofenac sodium meet heir label specifications as well as the BP 2009.Materials and Methods: Three brands of )iclofenac sodium were randomly selected in Pharmacies of Ishaka-Bushenyi Municipality, lushenyi. A total of 20 tablets of each brand ...

Assessment of The Chemical Composition and Pesticide Properties of Cassia Didymobotrya Ash on Myzus Persicae Affecting Tomato Crops in Ishaka

ABSTRACT Background: Myzus pe.rsicae (green peach aphids) are crop pests; they are among the most destructive insect pests on cultivated plants in temperate regions. Many of them are green in color, but others may be white wooly or black (McGravin,1993).Their damage to plants has made farming a complicated venture across the whole world. From the zo9logical standpoint, they are a highly successful group of organisms (Piper, 2007). The study was conducted to evaluate .the chemical composition ...

New Combination Methods of Detecting Drug Interaction And Monitoring Adverse Drug Reactions in "Close System Pharmacy"

ABSTRACTPharmacovigilance is an essential phenomenon in the rational use of medicine, providing information about ADR in general population. Tracking ADR in" close system pharmacy" whichhas relied on use of yellow forms and feed back following exposure to drugs has been inadequate. Alternative methods are therefore required. In the present study, the use of a combination of two methods to determine possible interactionsprior to dispensing and adverse drug reactions following ex...

Investigation of Antibacterial Activity, Phytochemical Screening and The Extractive Value of Different Solvents On Lawson/A Inermij(Henna) Plant Leaf Extract.

ABSTRACT. The purpose of this study was to evaluate the antibacterial activity, to determine the most efficiency extractive solvents and phytochemical profile of Hot water, Methanol alcohol and Lemon juice extract of Lawsonia inermis (henna) leaf. The plant attracted the attention of researchers because of its use as anti-infective agent. The oily and alcoholic extracts of the plant Lawsonia inermis dried powdered leaves were separately obtained by maceration, while the aqueous was obtained b...


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