Research Papers/Topics in Pharmacy
Home Management Of Uncomplicated Childhood Malaria By Mothers And Fathers In Lagos State, Nigeria.
ABSTRACT Malaria is a major public health disease. About 90% of all malaria deaths globally occur in Sub- Saharan Africa where Nigeria is located. Children are particularly susceptible resulting in high mortality. Mothers stay at home to care for children with malaria, thereby increasing absenteeism resulting in economic loss at the micro and macro levels. World Health Organization (WHO) in an attempt to ensure prompt treatment of uncomplicated childhood malaria, introduced home manage...
Pharmacognostic And Lactogenic Studies Of The Leaves Of Stachytarpheta Jamaicensis (L.) Vahl (Verbenaceae)
ABSTRACTBased on the ethnomedicinal use and belief that Stachytarpheta jamaicensis (SJ)can increase milk supply in lactating women, experimental studies were carried outto determine the effect of crude methanol extract (CME) and fractions of SJ leaveson serum PRL levels. The pharmacognostic standards, preliminary phytochemicalanalysis and acute toxicity study were also carried out. The fresh leaves werecollected, cleaned, air-dried and pulverized. A photomicroscope was used in thequalitative ...
Pharmaceutical Care And Syndromic Management Of Sexually Transmitted Infections (Stis) By Community Pharmacists In Lagos State
ABSTRACTSexually Transmitted Infections (STIs) are infections passed from one person to another during sexual contact though some are also passed from mother to child during pregnancy, birth or while breast feeding. STIs constitute an important public health problem. The early detection and treatment of STIs are important aspects of a comprehensive approach to reducing the spread of HIV. Although public-sector services are available even in the most resource-poor countries, they are not accep...
Medication Counselling Practice In Community Pharmacies In Lagos State, Nigeria
ABSTRACTCommunity pharmacies are major sources of medicines in most communities in Nigeria.Clients visit community pharmacies to seek help in medication therapy from communitypharmacist,who has a professional responsibility to protect the public from the dangers of selfmedication through provision of adequate medication counselling. It is however not known towhat extent community pharmacists fulfil this roles. The aim of this study was to examinethe nature, extent and adequacy of medication c...
Patient Medication Knowledge Governing Adherence to Asthma Pharmacotherapy: A Survey in Rural Lagos, Nigeria
ABSTRACT: Asthma is a chronic disease and often requires complex management. This study was undertaken in fourpharmacies–V-Ninat Pharmacy, Videc Chemists, Tomabel Pharmacy and Josbet Chemists, all in Isolo, Lagos, to determine thelevel of adherence to the anti-asthmatic drugs by asthmatic patients who participated in the study. Data was collected usingstructured questionnaires administered to patients coming into the pharmacies. The questionnaire was administered during aone-on-one intervie...
ANTI-DIABETIC AND ANTI-OXIDANT EVALUATION OF ANTHOCLEISTA DJALONENSIS A. CHEV AND ANTHOCLEISTA VOGELII PLANCH
Diabetes a major degenerative disease of global concern accounts for about 3.2 million deaths annually. Alpha-amylase inhibitors from plants are effective in managing postprandial hyperglycaemia which is significant in Type 2 diabetes. Search for natural anti-oxidants has increased recently because free radicals production has been linked to a number of diseases including diabetes. Anthocleista djalonensis and Anthocleista vogelii are used traditionally in Nigeria and...
Frequency Of Obesity Among Type 2 Diabetic Patients Attending A Tertiary Hospital In Lagos State Nigeria
ABSTRACTObesity and type 2 diabetes mellitus constitute major public health issues in modern societies worldwide. They have been linked in several ways. Obesity is involved in the pathologic process that culminates in the development of type 2 diabetes. The aim of this study was to assess the frequency of obesity in known type 2 diabetic patients and also to determine the presence of comorbidities associated with these two conditions. The study was carried out at Lagos University Teaching...
COMPRESSIONAL CHARACTERISTICS AND TABLETING PROPERTIES OF STARCHES OBTAINED FROM FOUR DIOSCOREA SPECIES
Abstract The compressional characteristics and tableting properties of starches from four yam species namely Dioscorea dumetorum Pax (Bitter); Dioscorea oppositifolia L (Chinese); Dioscorea alata L.DIAL2 (Water) and Dioscorea rotundata Poir (White) were investigated in comparison with corn starch. The physicochemical properties of the starches were evaluated using established methods while the compressional characteristics were analyzed using density measurements, and the Heckel and Kaw...
Additive effects of ciprofloxacin on the in-vitro activity of chloroquine against a clinical isolate of Plasmodium falciparum
ABSTRACTAs chloroquine and ciprofloxacin each possess substantial inhibitory activity against the schizonts of Plasmodium falciparum, it seems possible that a combination of the two drugs may be clinically useful. The effects on the erythrocytic stages of P. falciparum of combined treatment with chloroquine and ciprofloxacin were therefore evaluated in vitro, using the World Health Organization’s standardized micro test. When used alone, the median inhibitory concentration (IC50) of chl...
Antimicrobial and Anti-Inflammatory Activities of Extracts of Ficus Thonningii Blume (Moraceae)
ABSTRACT Infectious diseases and the associated inflammation pose a serious health problem worldwide, accounting for about 50% of all deaths in tropical countries. This is further complicated by the frequent development of bacterial resistance to many chemotherapeutic agents. These problems have necessitated the continuous search for new and effective drugs from plant materials. Thus, Ficus thonningii Blume (Moraceae), a plant used ethnomedicinally in West Africa for the treatment of so...
PRESCRIBING ERRORS AND INTERVENTION OUTCOMES IN SELECTED TERTIARY HOSPITALS IN NIGERIA
ABSTRACT Prescribing errors, particularly in the medical and paediatric specialties have been reported globally to affect up to 52.0% of hospitalized patients with potential to cause harm. Prescribing errors have however not been adequately investigated in Nigeria. This study was designed to carry out an in-depth evaluation of the nature, severity and causes of prescribing errors in three purposively selected tertiary hospitals in Nigeria with a view to providing pharmacist-led evidence...
A Survey of Antimalarial Drug Use Practices among Urban Dwellers in Abeokuta, Nigeria
ABSTRACT Drug-use pattern of anti-malarial has been associated with development of resistant strain and therapeutic failure. This descriptive cross-sectional study was carried out to assess anti-malarial drug-use practices among dwellers of Adigbe communities within Abeokuta environment. The study documented the knowledge, the attitude and behaviour of three hundred and fifty (350) respondents in terms of drug preference, attitude to drug use and the effects of non-compliance to antimalari...
PHARMACOGNOSY, Phytochemical Examination of the Plant species of Aframomum danielli and A. spectrum
ABSTRACT Aframomum danielli and Aframomum sceptrum (Zingiberaceae) have been studied in this research project for their phytochemical constituents, thin layer chromatographic analysis and insecticidal potentials. Phytochemical examination of the dried fruits showed the presence of alkaloids, terpenes, tannins and flavonoids. Saponin glycosides, cardiac glycosides, anthraquinone glycosides and cyanogenetic glycosides were absent in both plant species. The chromatograp...