Research Papers/Topics in Pharmacy

Biosynthesis of Silver Nanoparticles (AGNPS) Using Spondias Mombin Extract as a Bioreducing Agent

The field of nano science plays a crucial role in modern research and technology, offering unparalleled opportunities for innovation. Spondias mombin extract is used in this study as a bioreducing agent for the biosynthesis of silver nanoparticles (AgNPs). The properties of these nanoparticles are compared. As the color of the extract changed from colorless to brown and then dark silver during synthesis, the reduction of AgNO3 confirmed the effectiveness of S. motherbin extract as a bio-reduc...

Assessment of Heavy Metal Contents in Selected Herbal Medicines in Nigeria

The use of herbal medicines, despite the advancement in production of orthodox ones, has been on the increase, both in underdeveloped, developed and developing countries like Nigeria in particular. The approval of these herbal remedies by regulatory bodies like the National Agency for Food and Drug Administration Control, (NAFDAC) in Nigeria has further encouraged the use of herbal remedies by almost everybody. This research targets the estimation of the concentration of‘heavy metals’ in ...

Improving Stroke Prevention and Quantifying Outcomes Using a United States' City Model: Intervention Measurement through Population Survey and Hospital-Based Study

PROPOSAL: ABSTRACT Background: Currently stroke represents a serious problem in public health as one of the leading causes of mortality and morbidity worldwide [1-3] with developing countries accounting for 85% of global deaths from stroke [1, 3-5]. A very good example explains how stroke seems to be increasing in Nigeria and the case fatality is unacceptably high [6]. Good perceptions and knowledge of stroke; a population’s knowledge of the stroke risk factor profiles, and good quality...

Insulins: Analogues, Structure - Activity Relationship, Administration, Case Study, and Outcomes Studies

The seminar presentation delves into the evaluation of various Insulin analogues, structural modifications in relation to clinical response, cost-effectiveness and pharmacoeconomics especially with indigwnt patients and complex patients with co-morbidities that will be on it for a long time, and its value as well. This was presented at the University College Hospital Ibadan, Nigeria.

Hepatitis B/ Hepatitis C/ Decompensated Hepatic Disease/ Cirrhotic Disease of the Liver

This is a compilation of the slides presented at the University College Hospital Ibadan, Nigeria, which entails the literature review, epidemiology, case study on Hepatitis and associated disease conditions. This also explains the significance of Pharmacists in improving adherence to therapeutic regimens, understanding of the risk factors and various predispositions to liver diseases, the cost-effectiveness, cost-benefits analysis, and the medication therapy management in the assessment of He...

NON-HODGKIN LYMPHOMA

This is a compilation of the slides presented at the University College Hospital Ibadan, Nigeria, which entails the literature review, epidemiology, case study on Non-Hodgkin Lymphoma. This also explains the significance of Pharmacists in the cost-effectiveness, cost-benefits analysis, and the medication therapy management in the assessment of Non-Hodgkin Lymphoma 

Development of Lipid-Based Microsuspensions for Ophthalmic Delivery of Gentamicin

ABSTRACT The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human eye, extending contact time of drug with the cornea, increasing the penetration through the complex anatomical structure of the ey...

Evaluation of Anti-Ulcer Properties of Methanol Extract of Terminalia Superba Engl. & Diels (Combretaceae) Stem Bark

ABSTRACT Terminalia superba Engl. & Diels (Combretaceae), is a member of the genus Terminalia that comprises around 100 species distributed in tropical regions of the world. In Africa it is found along the coast of west and central Africa. It has different uses in traditional medicine such as antimalarial, anti-diabetic, anti-fungal, and anti-hypertensive in the areas where it is found. Most of these uses are yet to be scientifically investigated. The powdered stem bark of Terminalia superba ...

Physicochemical Study of the Interaction of Some Water Soluble Vitamins with Veegum

ABSTRACT. The interact ion of some water soluble vitamins -thiamine hydrochloride, riboflavin, nicotinarnide, pyridoxine hydrochloride and ascorbic acid with a xmntnlorillonite clay (Vecgum) has been investigated. The data obtained from the interactive studies fitted well on the isothermal equilibrium adsorption-tikc plots. Th3 results were analyzed using the Langmuir's equatim The Langmuirs p!3t yiclded reasonable linearity fiom which interactive constmts were ca!cc!atx!. The theoretical max...

Production, Characterization and Application of Multiple Modified Maize Starches in the Formulation of Oral Solid Dosage Forms of Gentamicin Sulphate

ABSTRACT Modified and unmodified starches in current use have limited applications in pharmaceutical industries. Extending the modification beyond the existing level may increase their applicability in dosage forms design especially for gentamicin sulphate, a difficult to formulate broad spectrum antibiotic for oral administration. In this research, maize starch was chemically modified to three levels (primary, secondary and tertiary) using pre-determined optimal conditions and established mo...

Formulation and Optimization of Artemether and Lumefantrine Calcium Alginate Capsules Using Inverse Gelation Technique

ABSTRACT Poorly water-soluble drug candidates are associated with dissolution, absorption and bioavailability challenges. Consequently, poor solubility and non-reproducible absorption from the gastrointestinal tract following oral administration constitute a biopharmaceutical concern to dosage form design and formulation. The use of lipid-based formulations to address this concern has been the choice of many scientists in the drug delivery domain. Artemether and Lumefantrine the drugs investi...

Determination of Antibacterial Activity of Whole Plant Extract of Phyllantltus Amarus Schum and Thonn (Kabamba Maliba) against Shigella Dysenteriae.

TABLE OF CONTENTS DECLARATION ............................................................................................................................ i DEDICATION ............................................................................................................................... ii APPROVAL ................................................................................................................................. iii ACKNOWLEDGMENT ...........................................

Assessment of Knowledge On Use of Artemether Lumefantrine in Management of Uncomplicated Malaria Among Outpatients at Klu-Th

ABSTRACT This study sought to assess the knowledge on the use of Artemether/ therapy in the management of uncomplicated malaria among out patients treated at KlU-TH. A cross sectional study design was employed in this study. Data was collected from August to October 2018 using a questionnaire by simple Random sampling and was entered and analyzed using Microsoft Excel spread sheet and Statistical Package of Social Sciences (SPSS) version 20 respectively. The results were presented in form of ...

Pharmaco-Economic Analysis of Brands of Antacid Formulations Available in Ishaka Town Using Titrimetric Method

ABSTRACT Pharmaco-economics involves comparing the cost and consequences of products and services and Cost-effectiveness is the relationship between cost and effectiveness of a given drug. ANC of an antacid is one of the ways of evaluating effectiveness of antacid brands. ANC (mEq per unit dose) is the ability of the antacid to neutralize gastric acid (Shery et al., 2013), and it should be greater or equal to 5mEq per unit dose(FDA), where a unit dose of 0.5g for tablets and 5ml for suspensio...

Comparative Pharmacopoeia Analysis of Selected Brands of Diclofenac Sodium Tablets Available in Western Uganda Pharmacies based On Bp 2009

ABSTRACT Jackground: Diclofenac is one of the most commonly used non-steroidal anti-inflammatory lrugs (NSAIDs) for the treatment of pain, rheumatism and other inflammatory conditions.Aim: ~his study aimed to investigate whether the selected brands of diclofenac sodium meet heir label specifications as well as the BP 2009.Materials and Methods: Three brands of )iclofenac sodium were randomly selected in Pharmacies of Ishaka-Bushenyi Municipality, lushenyi. A total of 20 tablets of each brand ...


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