Background: Making prognosis and identifying the patients at higher risk of mortality are important issues in breast cancer (BC) treatment. The aim of this study was to stratify BC case receiving mastectomy into prognostic risk categories using the Nottingham Prognostic Index (NPI).Methods: This was a retrospective review from January 2002 to December 2014 Results: Approximately 35% of all BCs diagnosed in our institution had undergone mastectomy. The mean age was 51.9 years. The mean size of...
Background: There is paucity of published data on head and neck tumours (HNTs) in Ghana, even the few studies available were conducted in the middle and southern belts of the country. The present study in northern Ghana, was conducted to study the histopathological characteristics of HNTs and offer recommendations. Methods: This retrospective study analysed HNTs for the past 10 years at the Tamale Teaching Hospital in northern Ghana. Results: There were 576 HNTs, with 66.0% benign and 34.0% m...
Background: Primary malignant orbito-ocular tumours (OOTs) frequently affect the younger age groups. Though mostly curable, they are a major cause of morbidity and even mortality in developing countries. The aim of this review was to describe the spectrum and clinico-pathological features of primary malignant OOTs in northern Ghana. Material and Methods: This study was a retrospective histopathological review from 1st June, 2013 – 30th June, 2019. Data were analysed using SPSS version 23 (S...
Background: More recently, contraception has been increasingly studied with regards to adolescent reproductive health. This study sought to investigate the knowledge, attitudes and perceptions of adolescents on contraception in the Bongo District. Material and methods: This was a cross-sectional descriptive study using structured questionnaires. Data was analysed using SPSS software (version 20) at two levels: gender and education. Results: The average age of first intercourse was 15.8 and 15...
Galactocele is a non-neoplastic cystic breast lesion found commonly in postpartum or lactating women.It may mimic neoplastic lesion because of the timing of its occurrence and or the clinicopathological changes in the affected breast tissue. It may thus pose a diagnostic challenge to clinicians in the absence of advanced imaging technology and histopathological examination. We present a 30-year-old woman para 7(5 alive, 2 dead) from the northern region of Ghana with an ulcerated giant galacto...
Background: Post-transfusion malaria in children under five years is associated with increased morbidity and mortality. The RDTs currently are used to supplement microscopy in the diagnosis of malaria in many endemic countries. However their efficiency as a screening tool for the detection of malaria in donors or in transfusion recipients has not been well evaluated. This study aimed to determine the efficiency of malaria RDT in the detection of post transfusion malaria. Material and methods:...
Background: Malignancies of the thyroid gland are common in certain parts of the world. In Ghana there are no available data on the trends and gender characteristics of thyroid malignancies (TMs). The aim of this retrospective study was to determine the trends and gender characteristics of TMs in the Department of Pathology. Keywords: Thyroid malignancies; Trends; Gender characteristics; Ghana Introduction Malignancies of the thyroid gland are relatively rare neoplasms worldwide, accounting f...
ABSTRACT Published data on GIT cancers in Northern Ghana is scanty. The aim of this review was to document the spectrum and the clinico-pathological characteristics of GIT cancers diagnosed in northern Ghana as a baseline data. Material and Methods: This was a histopathological review (n = 238) from 1st January, 2013 to 31st December, 2020. Data were analysed using SPSS software, version 26.0 (Chicago). Fisher’s exact test with a significance level of 0.05 was performed using GraphPad Prism...
Abstract The global food security and plant resources levels are continuously under threat from climate change, environmental pollution, population pressure, co-evolving plant pests and pathogens. Currently, scientists across the world are in pursuit of plant genotypes that can be resilient in growth and development amidst these stresses to enable survival of humans in the changing times. Therefore, to effectively select plants that have known and favorable resistance or tolerance levels aga...
Abstract Zoonotic diseases, such as brucellosis, Q fever and Rift Valley fever (RVF) caused by Brucella spp., Coxiella burnetii and RVF virus, respectively, can have devastating effects on human, livestock, and wildlife health and cause economic hardship due to morbidity and mortality in livestock. Coinfection with multiple pathogens can lead to more severe disease outcomes and altered transmission dynamics. These three pathogens can alter host immune responses likely leading to increased mo...
Abstract: Sweet orange (Citrus sinensis Osbeck) is grown throughout the world and provides the greatest fresh fruit production of any citrus groups. In freshly harvested fruits, as the quality deterioration and the susceptibility of the stored products to decay caused by microbial spoilage and pathogens increases progressively. The application of an edible coating onto the fruit surface modifies the internal atmosphere in the same way that does plastic films by increasing the carbon dioxide ...
Abstract: Phytopathogenic fungi result in a significant loss in agricultural production. The use of bio fungicides to manage these fungal pathogens has become a more appealing option than using conventional synthetic fungicides since they are relatively environmentally safe. Chitinolytic enzymes are environmentally friendly antifungal agents used to control fungal phytopathogens. Therefore, this study was conducted to extract chitinase enzyme from fungi and determine the fungicidal effect of...
Abstract: Infectious diseases are the critical problems of the world as a result of the emergence of different antimicrobial resistant microorganisms. Medicinal plants play great roles in the treatment of various infectious diseases. Catha edulis, of the Celastraceae family, is a natural stimulant found as a flowering evergreen tree and is widespread in Africa and southern parts of Arabia. Therefore, the aim of the study was to detect the presence of the main secondary compounds classes from...
Abstract: This study evaluated the performance of five eri (Bere, Cross, EKPR, EKSCR, India) and five mulberry (China-2, Kenya-2, Kenya-3, Kenya-4, Korea-1) silkworm strains and observe the level of diseases incidence on farmer management condition in between March and May 2018, in Arba Minch. The experiment was laid out in Completely Randomized Design (CRD) with five replications. The study revealed that mature larvae of eri silkworm strains significantly varied on nutritional indices and s...
Abstract: The livelihood of the community in the study areas is highly dependent on the production of wheat crop. But the production of wheat crop is challenged by biotic and abiotic factors in the study area. Among the biotic factors rust disease is one and highly affecting the production and productivity of the crop. This study aimed to identify the adaptation strategies against emerging wheat rust disease and determinants of farmers’ choice of adaptation strategies against this disease....