Research Papers/Topics in Bioinformatics

Phylogenetic and In Silico Analysis of Niemann-pick type C1 (NPC1) Transporter Required for Ebola Viral Entry

Ebola  virus  (EBOV) has recently emerged as a highly virulent organism of concern to humans. The pathology behind the hemorrhagic fever within an EBOV host remains largely unclear, and demands rather novel therapeutics to effectively eradicate this virus. The Niemann-pick type C1 (NPC1) protein cholesterol transporter is required for EBOV entry and internalization into a mammalian host cell. On this premise, an organism’s NPC1  can  decide  the  virus-species  specificity.  Here, ...

The Role of Scientists Warning in Shifting Policy from Growth to Conservation Economy

We are pleased to see the three follow- up letters concerning our “World Scientists’ Warning to Humanity: A Second Notice” (Ripple et al. 2017). Each letter expresses a thoughtful, heartfelt response to our paper. We agree in how they describe the need to get more scientists into policymaking positions (Dror), to create a new global environmental ethic (Skubała), and to recognize economic growth as a major driver of environmen...

The Social Economic Effects of Fuel Scarcity in Nigeria

INTRODUCTION Just like water and air is important to the living human being for daily duties and a hitch – free survival, the importance of fuel to automobile cannot be over looked.  A typical situation is in the cases halts because of the fact that there is shortage of fuel.  The importance of fuels in this our developing and technically inclined economy is fast like the mixture of oil and salt as far as t...

Influence of genetics and environment on grain quality.

AbstractWheat grain quality are strongly influenced by the effects of environment during grain fill. Environmental variables such as temperature, water and fertilizer influence the rate and duration of wheat grain development, protein accumulation and starch deposition in unique ways, and by different mechanisms. The effects of environment are superimposed on the intrinsic temporal patterns of gene expression during grain development. Integration of genomic and proteomic studies with developm...

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