Abstract: Antibiotic resistance has been a growing worldwide public health issue. The World Health Organization (WHO) has stated that the search for new antibiotics is slow, while antibiotic resistance is growing. WHO has also declared that antibiotic resistance is one of the top 10 global public health threats facing humanity in the 21st century. Therefore, this review discusses the potential of metal-based drugs as antibacterial agents from the period of the early 2000s to date. The review...
Abstract: Human African Trypanosomiasis (HAT) is present in 36 sub-Saharan African countries. The disease is easier to treat in early stage than late stage when treatment with melarsoprol is responsible for significant fatality. Therefore there is need to develop a diagnostic test for early detection before progression of the disease into the late stage. Currently available tests have poor sensitivity. Thus highly sensitive methods are needed for the detection of the parasite in human blood....
Abstract: Ethnobotanical analyses highlight therapeutic and chemotypic variations of geographically and ecologically diverse Murraya koenigii (Spreng) samples. However, the genetic correlation of this observation remains obscure. The present study aimed at studying the intraspecific genetic variation of Murraya koenigii and the possible effect on the bioactivity of volatiles of plant samples collected from four different geographical locations of Kenya. Genomic DNA isolated from various plan...