Biotechnology Research Papers/Topics

Potential human pathogenic bacteria in five hot springs in Eritrea revealed by next generation sequencing

Abstract Human pathogens can survive and grow in hot springs. For water quality assessment, Escherichia coli or Enterococci are the main thermotolerant enteric bacteria commonly used to estimate the load of pathogenic bacteria in water. However, most of the environmental bacteria are unculturable thus culture methods may cause bias in detection of most pathogens. Illumina sequencing can provide a more comprehensive and accurate insight into environmental bacterial pathogens, which can be use...

In vivo antimalarial and acute toxicity properties of hexane and chloroform extracts from Clausena anisata (Willd.) Benth

Abstract Background: Drugs are an important tool for control of malaria. However, drug resistance is likely to compromise available antimalarial drugs with time. As a result, efforts are being directed towards discovery and development of novel and affordable malaria drug molecules including those from medicinal plants. Objectives: To investigate suppressive, curative, prophylactic and acute toxicity properties of hexane and chloroform extracts of Clausena anisata against murine malaria. Met...

Development of cost-effective media for the culture of Chilo partellus larvicide in Kenya

Abstract Stem borers (Chilo partellus) are important field insect pests of maize (Zea mays L.) and sorghum (Sorghum bicolor L.) in Africa. They account for more than 30% yield losses depending on the composition of the pest community. C. partellus larvicide like Bacillus thuringiensis have been widely and effectively used in C. partellus control programs, but the industrial production of theses bacilli is expensive. Here we have attempted to develop three cost-effective media, based on legum...

Characterization of Uromyces appendiculatus isolates collected from snap bean growing areas in Kenya

Abstract Bean rust (Uromyces appendiculatus (Pers.:Pers.) Unger var. appendiculatus) is one of the most devastating and variable pathogens of common bean (Phaseolus vulgaris L.) worldwide that can cause total crop loss. Characterization of bean rust races can help in screening resistant materials during gene pyramiding. The aims of the present research were first, to characterize bean rust isolates collected from snap bean growing areas in Kenya. Secondly, to identify which of the available ...

Sustainability strategies and performance of public universities in Kenya

Abstract The current operational setup in Kenya’s Universities is a turbulent one and highly competitive market condition. To ensure survival and sustainability, public universities require to adopt and implement competitive strategies. Many scholars have investigated sustainability efforts by universities in pursuit of performance, however, it is still not clear how sustainable strategies have the greatest influence on the performance of Public Universities. Thus, the study set to establi...

Control of stem borers and striga in African cereals: a low input push-pull approach with rapidly expanding impact

Abstract: A system which comprises intercropping between rows of maize with plants that repel stem borers and attract natural enemies, and which also dramatically reduce the level of striga infestation, combined with a surrounding crop of plants that trap out pests, has been developed for use by resource-poor farmers in sub-Saharan Africa.The intercrop and trap crops provide forage for cattle and goats. The technology is called “push-pull”. It is knowledge-intensive and there are lessons...

Containment Studies of TransgenicMosquitoes in Disease Endemic Countries:The Broad Concept of Facilities Readiness

Abstract: Genetic strategies for large scale pest or vector control using modified insects are not yet operational in Africa,and currently rely on import of the modified strains to begin preliminary, contained studies. Early involvementof research teams from participating countries is crucial to evaluate candidate field interventions. Following therecommended phased approach for novel strategies, evaluation should begin with studies in containmentfacilities. Experiences to prepare facilities...

Research Grant Proposal - Improvement of microbial cells for the generation of biofuel from solid

A grant proposal presenting plans for a research project, possibly closely related to current research project, written in the form of a case for support for a small grant, such as an international short-term visit, a travel grant for a conference, or a studentship. This was submitted to the University of Lincoln as an assessment in one of the modules.

A lignin-eating bacterium could aid in the clean-up of some dye-contaminated sites

A research news short article featuring two published research papers in the field of biosciences. This was submitted to the University of Lincoln as an assessment.

CHEMICAL COMPOSITION, PROFILING AND ANTIFUNGAL ACTIVITY OF THE ESSENTIAL OIL AND PLANT EXTRACTS OF MESEMBRYANTHEMUM EDULE (L.) BOLUS LEAVES

Abstract Background: Essential oil from Mesembryanthemum edule leaves have been used by the Eastern Cape traditional healers for the treatment of respiratory tract infections, tuberculosis, dysentery, diabetic mellitus, laryngitis and vaginal infections. The investigation of bioactive compounds in the essential oil of this plant could help to verify the efficacy of the plant in the management or treatment of these illnesses. Materials and methods: Various concentrations of the hydro-distill...