ABSTRACT Background: Neonatal Hepatitis B viral (HBV) infection is a public health concern worldwide. Prevalence of chronic HBV infection in Ghana is in excess of 8.0 %, and was 2.3 per 100,000 in Sekondi Takoradi in 2017. The purpose of the study was to determine maternal factors associated with transmission of Hepatitis B to newborn babies. Methods: A cross-sectional study involving pregnant women was carried out at antenatal units of selected hospitals in the Sekondi Takoradi Metropolis. Hepatitis B positive pregnant women of 34-37 weeks gestation were recruited into the study. Demographic information was collected from the mothers and a review of their antenatal record books performed to extract data on their medical and obstetric history. Maternal venous blood was collected and Hepatitis B viral load and e-antigen level assessed. Cord blood samples were collected and tested for Hepatitis B virus infection in the babies. Results: Eighty-nine Hepatitis B positive mothers had their babies screened for HBV. Prevalence of neonatal HBV was found to be 17.98% (16/89). Birthweight of infected babies was significantly higher than the uninfected babies (3.33kg vs. 3.12kg, p-value=0.043). Viral load (935.18 IU/mL) of mothers whose babies were not infected was lower compared to viral load (4178.63 IU/mL) of mothers of the infected babies (p-value
AYEPAH, C (2021). Maternal Factors Associated With Hepatitis B Transmission To Neonates; A Study Selected Antenatal Clinics In The Sekondi Takoradi Metropolis And Effia Kwesimintsim Municipality, 2019.. Afribary. Retrieved from https://afribary.com/works/maternal-factors-associated-with-hepatitis-b-transmission-to-neonates-a-study-selected-antenatal-clinics-in-the-sekondi-takoradi-metropolis-and-effia-kwesimintsim-municipality-2019
AYEPAH, CHRISTABEL "Maternal Factors Associated With Hepatitis B Transmission To Neonates; A Study Selected Antenatal Clinics In The Sekondi Takoradi Metropolis And Effia Kwesimintsim Municipality, 2019." Afribary. Afribary, 06 Apr. 2021, https://afribary.com/works/maternal-factors-associated-with-hepatitis-b-transmission-to-neonates-a-study-selected-antenatal-clinics-in-the-sekondi-takoradi-metropolis-and-effia-kwesimintsim-municipality-2019. Accessed 26 Dec. 2024.
AYEPAH, CHRISTABEL . "Maternal Factors Associated With Hepatitis B Transmission To Neonates; A Study Selected Antenatal Clinics In The Sekondi Takoradi Metropolis And Effia Kwesimintsim Municipality, 2019.". Afribary, Afribary, 06 Apr. 2021. Web. 26 Dec. 2024. < https://afribary.com/works/maternal-factors-associated-with-hepatitis-b-transmission-to-neonates-a-study-selected-antenatal-clinics-in-the-sekondi-takoradi-metropolis-and-effia-kwesimintsim-municipality-2019 >.
AYEPAH, CHRISTABEL . "Maternal Factors Associated With Hepatitis B Transmission To Neonates; A Study Selected Antenatal Clinics In The Sekondi Takoradi Metropolis And Effia Kwesimintsim Municipality, 2019." Afribary (2021). Accessed December 26, 2024. https://afribary.com/works/maternal-factors-associated-with-hepatitis-b-transmission-to-neonates-a-study-selected-antenatal-clinics-in-the-sekondi-takoradi-metropolis-and-effia-kwesimintsim-municipality-2019