Abstract
Objective: Since the implementation of a series of blood donation safety improvements in Kenya, information about
seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors especially in
high HIV burden regions of Homabay, Kisumu and Siaya counties remain scanty. A cross-sectional study examining
HIV, syphilis, hepatitis B and C virus sero-markers and associated determinants was conducted among voluntary blood
donors. Their demographic characteristics and previous risk exposure were recorded in a pre-donation questionnaire,
while blood samples collected were screened for hepatitis B, hepatitis C, human immunodeficiency viruses by ELISA
and RPR (syphilis), then confirmed using CMIA.
Results: Overall TTIs seroprevalence was 114 (9.4%), distributed among HIV, HBV, HCV and syphilis at 14 (1.15%), 42
(3.46%), 39 (3.21%) and 19 (1.56%), respectively, with co-infections of 3 (0.25%). There were no significant differences
in proportions distributions among demographic variables. However, high risk sex was significantly associated with
higher odds of HBV infections [> 1 partner vs. 0–1 partner; odd ratio (OR) 2.60; 95% confidence interval (CI) 1.098–6.86;
p = 0.046]. In conclusion, a substantial percentage of blood donors still harbor transfusion transmissible infections
despite recent safety improvements with greater majority cases caused by HBV infections arising from previous exposure
to high risk sex.
Onyango1, C (2021). Of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya. Afribary. Retrieved from https://afribary.com/works/of-transfusion-transmissible-infections-among-voluntary-blood-donors-in-homabay-kisumu-and-siaya-counties-in-western-kenya
Onyango1, Calleb "Of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya" Afribary. Afribary, 06 May. 2021, https://afribary.com/works/of-transfusion-transmissible-infections-among-voluntary-blood-donors-in-homabay-kisumu-and-siaya-counties-in-western-kenya. Accessed 22 Nov. 2024.
Onyango1, Calleb . "Of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya". Afribary, Afribary, 06 May. 2021. Web. 22 Nov. 2024. < https://afribary.com/works/of-transfusion-transmissible-infections-among-voluntary-blood-donors-in-homabay-kisumu-and-siaya-counties-in-western-kenya >.
Onyango1, Calleb . "Of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya" Afribary (2021). Accessed November 22, 2024. https://afribary.com/works/of-transfusion-transmissible-infections-among-voluntary-blood-donors-in-homabay-kisumu-and-siaya-counties-in-western-kenya