Efficacy and Challenges in Usage of Gut Microbiome in Management of Hypertension

Even though there is plethora of scientific literature available regarding the role of gut microbiome in hypertension, but till date, 

there is neither clarity nor established guidelines and consensus regarding strain-specificity for hypertension in any of the existing national and international guidelines like European Society of Hypertension (ESH), International Society of Hypertension (ISH) etc. Innovative microbiome-based or targeted medication related research, which have the potential to revolutionize the treatment of hypertension are highly recommended in future because effects of probiotics can be specific to certain probiotic species and strains. Recommendations for their use in the clinical practice or in research studies need to be compulsorily species and strain specific and interpretation of data from studies involving mixture of probiotic supplements can be misleading in terms of beneficial effects, efficacy and safety and should be cautious.