Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats
The effects of the aqueous leaf extract of Basella alba on haematological and biochemical parameterswere studied in Wistar strain albino rats. Twenty four (24) Wistar strain albino rats were randomlydistributed into four groups of six (6) rats each. Group I rats served as control and received 10 ml/kg ofnormal saline, while group II, III and IV received 60, 80 and 100 mg/kg of aqueous leaf extract of B. alba,respectively, for two weeks. Administration of the extract was done orally. At the en...
Virgin Coconut Oil: Remedial Effects on Renal Dysfunction in Diabetic Rats
Renal dysfunction is nowa prevalent complication of diabetesmellitus. Therefore, this study was carried out to evaluate the remedialeffects of virgin coconut oil (VCO) on renal dysfunction in diabetic rats. Fifteen albinoWistar rats were divided into 3 groups thatcomprise normal control group (Group I) and diabetic control group (Group II) fed with normal rat chows and a diabetic test group(Group III) fed with 10% VCO diet. Group II and Group III were made diabetic by single intraperitoneal i...
Dietary Consumption of Virgin Coconut Oil Ameliorates Lipid Profiles in Diabetic Rats
Virgin coconut oil (VCO) is a saturated fat with promising antidiabetic properties but its ameliorative effect on lipid profilesin diabetics is rarely reported. Therefore, in this study, a total of fifteen (15) male rats weighing 200–250 g were divided into 3experimental groups (𝑛 = 5).Group I (control) andGroup II (diabetic control group) were fed a normal rat chowwhile Group III(diabetic test group) was fed a 10% VCO diet for 3 weeks. Group II and Group III were made diabetic by intrap...
Virgin Coconut Oil (VCO) supplemented diet ameliorates blood glucose, renal tissue and antioxidant enzymes in diabetic rats
Untreated hyperglycaemia leads to kidney damage through oxidative stress of the kidney tissues with resultantcompromise of the antioxidant enzymes. According to research, Virgin Coconut Oil (VCO) has been reported tohave hypoglycaemic and anti-diabetic properties. Therefore, this study was designed to investigate theameliorative effects of VCO supplemented diet on blood glucose, renal tissues and antioxidant enzymes indiabetic rats. The study was carried out on fifteen male rats weighing 150 ...
Virgin coconut oil dietary consumption ameliorates abnormal haemostatic parameters in diabetic rats
Introduction: Virgin coconut oil (VCO), a saturated fat,has been reported to have anti-diabetic properties and thereis dearth of information on its potency to correct abnormalhaemostatic parameters associated with diabetic patients.Objectives: Therefore, this study was carried out toinvestigate effect of VCO consumption on abnormalhaemostatic parameters in diabetic rats.Materials & Methods: A total of fifteen (15) male ratsweighing 200–250g were divided into three (3) experimentalgroups: No...
Long Term Consumption of Coconut Oil Diet Increased Anxiety Related Behaviour in CD1 Mice
The effect of prolonged consumption of virgin coconut oil (VCO) diet on anxiety was assessed in CD1 mice using the Open field (OF), Elevated plus maze (EPM) and Light/dark box (LD box) tests. Thirty male CD1 mice (28.4-32.5 g bw) divided into 3 groups (n=10 each) were given normal rodent chow (control), 5% (w/w) and 20% (w/w) VCO diet respectively and water ad libitum for 23 days. The OF test showed increased grooming (p< 0.05) in both 5% and 20% VCO groups versus control, and higher Freeze f...