The effects of the aqueous leaf extract of Basella alba on haematological and biochemical parameters
were studied in Wistar strain albino rats. Twenty four (24) Wistar strain albino rats were randomly
distributed into four groups of six (6) rats each. Group I rats served as control and received 10 ml/kg of
normal saline, while group II, III and IV received 60, 80 and 100 mg/kg of aqueous leaf extract of B. alba,
respectively, for two weeks. Administration of the extract was done orally. At the end of the treatment
period, haematological parameters (red blood cell count, white blood cell count, platelet count, packed
cell volume and haemoglobin concentration) and biochemical parameters (alkaline phosphatase (ALP),
alanine aminotransaminase (ALT) and aspartate aminotransaminase (AST)) were determined. The
results showed that B. alba significantly increased (p < 0.05, 0.01) red blood cell count, white blood cell
count, packed cell volume, haemoglobin concentration and platelet count. However, the extract
significantly (p < 0.05, 0.01) reduced the activity of the liver enzymes such as ALP, ALT and AST. The
decreases were dose dependent. In conclusion, adding B. alba leaves as part of daily diet may reduce
anaemia and maintain good health.
Akinnuga, A., , B , , O , , A , M.2, A , , O , O.3, J , , O , A.3, O , , O , and, C & , N (2018). Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats. Afribary. Retrieved from https://afribary.com/works/effects-of-aqueous-extract-of-basella-alba-leaves-on-haematological-and-biochemical-parameters-in-albino-rats
Akinnuga, Akinjide, et. al. "Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats" Afribary. Afribary, 28 Mar. 2018, https://afribary.com/works/effects-of-aqueous-extract-of-basella-alba-leaves-on-haematological-and-biochemical-parameters-in-albino-rats. Accessed 26 Apr. 2024.
Akinnuga, Akinjide, Bamidele , O.1* , Akinnuga , A. M.2 , Olorunfemi , J. O.3 , Odetola , O. A.3 , Oparaji , C. And and N.3 . "Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats". Afribary, Afribary, 28 Mar. 2018. Web. 26 Apr. 2024. < https://afribary.com/works/effects-of-aqueous-extract-of-basella-alba-leaves-on-haematological-and-biochemical-parameters-in-albino-rats >.
Akinnuga, Akinjide, Bamidele , O.1* , Akinnuga , A. M.2 , Olorunfemi , J. O.3 , Odetola , O. A.3 , Oparaji , C. And and N.3 . "Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats" Afribary (2018). Accessed April 26, 2024. https://afribary.com/works/effects-of-aqueous-extract-of-basella-alba-leaves-on-haematological-and-biochemical-parameters-in-albino-rats