Research Papers/Topics in Physiology

Hypoglycemic and Antioxidant Potentials of Aqueous Extract of Eucalyptus Globulus in Experimentally-Induced Diabetic Rats

AbstractBackground: Evaluation of the medicinal uses of plants remains a growing field of research. This study investigated the effects of Eucalyptus globules on alloxan -induced diabetic rats.Materials and Methods: Thirty male albino rats were randomized into 5 groups (n=6).Group A served as the control and was maintained on standard rat chow and water ad’libitum. Diabetes was induced in Group C, D and E animals by intraperitoneal administration of alloxan monohydrate (150 mg/kg).Groups B ...

Endocrine and Neuroendocrine Factors Regulating Testicular Functions

The spermatogenic and steroidogenic functions of the testes is finely regulated by the brain (on stimulation), the master endocrine gland, and local factors produced by the testes. During intrauterine life the proliferation of primitive germ cells and the formation of the testes is carefully directed by testosterone, secreted by leydig cell on activation by human chorionic gonadotropin (HCG) released by the placenta. After birth, hormonal regulation of testes stop and the testes remain quice...

Effects of vernonia amygdalina on neurobehavioral activities of albino rats

         TABLE OF CONTENTS Preface Certification Dedication Acknowledgements Table of contents List of tables List of figures Abstract CHAPTER ONE 1.       Introduction 1.1     cannabis sativa 1.2     cannabis and cannabinoids 1.3     Vernonia amygdalina CHAPTER TWO 2        Literature Review 2.1 &nbsp...

Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats

The effects of the aqueous leaf extract of Basella alba on haematological and biochemical parameterswere studied in Wistar strain albino rats. Twenty four (24) Wistar strain albino rats were randomlydistributed into four groups of six (6) rats each. Group I rats served as control and received 10 ml/kg ofnormal saline, while group II, III and IV received 60, 80 and 100 mg/kg of aqueous leaf extract of B. alba,respectively, for two weeks. Administration of the extract was done orally. At the en...

Virgin Coconut Oil: Remedial Effects on Renal Dysfunction in Diabetic Rats

Renal dysfunction is nowa prevalent complication of diabetesmellitus. Therefore, this study was carried out to evaluate the remedialeffects of virgin coconut oil (VCO) on renal dysfunction in diabetic rats. Fifteen albinoWistar rats were divided into 3 groups thatcomprise normal control group (Group I) and diabetic control group (Group II) fed with normal rat chows and a diabetic test group(Group III) fed with 10% VCO diet. Group II and Group III were made diabetic by single intraperitoneal i...

Dietary Consumption of Virgin Coconut Oil Ameliorates Lipid Profiles in Diabetic Rats

Virgin coconut oil (VCO) is a saturated fat with promising antidiabetic properties but its ameliorative effect on lipid profilesin diabetics is rarely reported. Therefore, in this study, a total of fifteen (15) male rats weighing 200–250 g were divided into 3experimental groups (𝑛 = 5).Group I (control) andGroup II (diabetic control group) were fed a normal rat chowwhile Group III(diabetic test group) was fed a 10% VCO diet for 3 weeks. Group II and Group III were made diabetic by intrap...

Virgin Coconut Oil (VCO) supplemented diet ameliorates blood glucose, renal tissue and antioxidant enzymes in diabetic rats

Untreated hyperglycaemia leads to kidney damage through oxidative stress of the kidney tissues with resultantcompromise of the antioxidant enzymes. According to research, Virgin Coconut Oil (VCO) has been reported tohave hypoglycaemic and anti-diabetic properties. Therefore, this study was designed to investigate theameliorative effects of VCO supplemented diet on blood glucose, renal tissues and antioxidant enzymes indiabetic rats. The study was carried out on fifteen male rats weighing 150 ...

Virgin coconut oil dietary consumption ameliorates abnormal haemostatic parameters in diabetic rats

Introduction: Virgin coconut oil (VCO), a saturated fat,has been reported to have anti-diabetic properties and thereis dearth of information on its potency to correct abnormalhaemostatic parameters associated with diabetic patients.Objectives: Therefore, this study was carried out toinvestigate effect of VCO consumption on abnormalhaemostatic parameters in diabetic rats.Materials & Methods: A total of fifteen (15) male ratsweighing 200–250g were divided into three (3) experimentalgroups: No...

Long Term Consumption of Coconut Oil Diet Increased Anxiety Related Behaviour in CD1 Mice

The effect of prolonged consumption of virgin coconut oil (VCO) diet on anxiety was assessed in CD1 mice using the Open field (OF), Elevated plus maze (EPM) and Light/dark box (LD box) tests. Thirty male CD1 mice (28.4-32.5 g bw) divided into 3 groups (n=10 each) were given normal rodent chow (control), 5% (w/w) and 20% (w/w) VCO diet respectively and water ad libitum for 23 days. The OF test showed increased grooming (p< 0.05) in both 5% and 20% VCO groups versus control, and h...

Anti-Diabetic and Antioxidant Potentials of Aqueous Extract of Eucalyptus Globulus in Experimentally-Induced Diabetic Rats

Anti-diabetic and Anti-oxidant potentials of Aqueous Extract of Eucalyptus Globulus in experimentally induced diabetic rats.

Effects of aqueous extract of Moringa oleifera seed on serum cortisol and body weight of adult wistar rats

Abstract The effect of aqueous extract of Moringa oleifera seed on serum cortisol and body weights was investigated in 24 adult Wistar rats for 21 days. Dried Moringa oleifera seeds were powdered by an electric blender. With the aid of an oven regulated at 400C and water, the Moringa oleifera seed extract was produced. The extract was dissolved in 5% Tween 80 solution to produce aqueous extract with concentration of 200mg/ml. The rats with a mean body weight of 144±43.1g were divi...

BLOOD FLOW MEASUREMENT

Blood is a specialized connective tissue in fluid form that flows through the entire body of a person or animal. Blood flow is the continuous circulation of blood through the cardiovascular system to body tissues and organs. An adequate amount of blood supply is necessary for the proper functioning of all body organs. This is vital as the blood carries and supplies body tissues and organs with its daily metabolic requirements while it ...

CELL TO CELL SIGNALLING - HOW CELL COMMUNICATE WITH EACH OTHER TO PROMOTE AND SUSTAIN LIFE

Cell to cell signaling refers to the transfer of information from one cell to another. This is also called cell signaling or intercellular communication. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and ...

CLINICAL ASPECT OF SPINAL MOTOR SYSTEM - THE BROWN SEQUARD SYNDROME

Brown-Séquard syndrome, also known as Brown-Séquard's hemiplegia and Brown-Séquard's paralysis, is a loss of sensation and motor function (paralysis and anesthesia) that is caused by the lateral hemisection (cutting) of the spinal cord. This may be seen most often in the cervical (neck) or thoracic spine. Other synonyms are hemiparaplegic syndrome, hemiplegia ethemiparaplegiaspinalis, and spinal hemiparaplegia.&nbs...

FACTORS THAT CAN UPREGULATE AND DOWNREGULATE DIGESTION AND ABSORPTION OF CARBOHYDRATE

Digestion is the breakdown of complex food substances into simple and absorbable form by the aid of enzymes using a process known as hydrolysis. Carbohydrate basically are divided into three: Polysaccharides (example Starch), Disaccharides (Sucrose and Lactose), and monosaccharides (Fructose, Galatose and Glucose). Almost all the carbohydrates of the diet are either large polysaccharides or disaccharides, which are combinations...


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