ISOLATION AND CHARACTERIZATION OF LUPEOL FROM THE METHANOL LEAF EXTRACT OF TAPINANTHUS DODONEIFOLIUS GROWING ON VITEX DONIANA
Tapinanthus dodoneifolius belongs to the family Loranthaceae and is widely distributed in West Africa, Europe and Asia, commonly known as mistletoe. It exhibits a wide array of pharmacological activities including antimalarial, anticonvulsant, anti- microbial, and is effective in the relief of menstrual and stomach pain. Lupeol, a pentacyclic triterpenoid was isolated for the first time from the methanol leaf extract of Tapinanthus dodoneifolius and characterized by spectral analysis. Th...
PHYTOCHEMICAL SCREENING AND IN VIVO ANTIMALARIAL ACTIVITY OF THE METHANOL LEAF EXTRACT OF TAPINANTHUS DODONEIFOLIUS (DC) DANSER GROWING ON VITEX DONIANA
Malaria is a major public health problem in the world especially in Africa, with an estimated two million children and pregnant women worldwide dying of malaria yearly, primarily because of Plasmodium falciparum and its complications. Preliminary phytochemical screening of the methanol leaf extract revealed the presence of triterpenoids, saponins, tannins, terpenoids, flavonoid, cardiac glycoside, carbohydrate and alkaloids. The in vivo antimalarial activity of the crude methanol leaf ...