ABSTRACT
Background: Wound infections mostly caused by Pseudomonas are on the increase in hospitals in Ghana. Most of these infected wounds are very difficult to treat with available antibiotics. This failure of treatment has resulted in increased need for healthcare, undue financial burden on both hospitals and patients and finally death of many of these patients. This has become a source of worry for both patients and healthcare providers in Ghana. General Aim: The main aim of this study was to characterize antimicrobial resistant bacteria from infected wounds at the Korle-Bu Teaching Hospital (KBTH) and the Koforidua Regional Hospital (KRH) in Ghana. Methodology: Two hundred and twenty-two (222) consecutive, non-duplicated patients with infected wounds attending the KBTH and the KRH were swabbed. Bacteria were isolated, identified and characterized using standard microbiological methods. Antimicrobial susceptibility of the clinical isolates was determined according to the Clinical Laboratory Standard Institute guidelines (CLSI). Phenotypic and molecular techniques were used to detect carbapenemresistant Pseudomonas strains and presence of metallo-beta-lactamase (MBL) genes, bla VIM-type, bla SPM-type and bla IMP-type. Vital clinical information of patients was obtained from folders at the time of sample collection and analyzed. Results: A total number of 194 bacteria were isolated from patients attending KBTH and KRH. The bacteria isolates included Pseudomonas spp. 92(47.4%), Proteus spp. 27(13.9%), Citrobacter spp. 20(10.3%), Escherichia coli 15(7.7%), Klebsiella spp. 15(7.7%), Staphylococcus aureus 14(7.2%), Enterobacter spp.
ADDO, F (2021). Characterization of antimicrobial resistant pseudomonas spp. And other bacteria from infected wound. Afribary. Retrieved from https://afribary.com/works/characterization-of-antimicrobial-resistant-pseudomonas-spp-and-other-bacteria-from-infected-wound
ADDO, FRANCIS "Characterization of antimicrobial resistant pseudomonas spp. And other bacteria from infected wound" Afribary. Afribary, 27 Apr. 2021, https://afribary.com/works/characterization-of-antimicrobial-resistant-pseudomonas-spp-and-other-bacteria-from-infected-wound. Accessed 18 Dec. 2024.
ADDO, FRANCIS . "Characterization of antimicrobial resistant pseudomonas spp. And other bacteria from infected wound". Afribary, Afribary, 27 Apr. 2021. Web. 18 Dec. 2024. < https://afribary.com/works/characterization-of-antimicrobial-resistant-pseudomonas-spp-and-other-bacteria-from-infected-wound >.
ADDO, FRANCIS . "Characterization of antimicrobial resistant pseudomonas spp. And other bacteria from infected wound" Afribary (2021). Accessed December 18, 2024. https://afribary.com/works/characterization-of-antimicrobial-resistant-pseudomonas-spp-and-other-bacteria-from-infected-wound