Research Papers/Topics in Microbiology

Fine specificity of anti-MSP119 antibodies and multiplicity of Plasmodium falciparum Merozoite Surface Protein 1 types in individuals in Nigeria with sub-microscopic infection

Abstract Background: The absence of antibodies specific for the 19 kDa C-terminal domain of merozoite surface protein 1 (MSP119) has been associated with high-density malaria parasitaemia in African populations. The hypothesis that a high prevalence and/or level of anti-MSP119 antibodies that may inhibit erythrocyte invasion would be present in apparently healthy individuals who harbour a sub-microscopic malaria infection was tested in this study. Methods: Plasma samples were collected...

NUTRITIONAL AND BIOCHEMICAL CHARACTERISTICS OF LACTIC ACID BACTERIA-CHALLENGED SORGHUM AND ITS FERMENTATION PRODUCT

ABSTRACT Sorghum is one of the major cereals malted for the brewing of beer. The conditions of transport and storage of this cereal predispose it to contamination by microbes thus affecting the quality of the end products. The contamination is usually controlled by treating the sorghum with chemicals, which however alter the chemical constituents of the sorghum. Therefore, the need to seek alternative functional methods of control of microbial contaminants becomes imperative. This s...

Potentials of Walnut (Tetracarpidium Conophorum Mull. Arg) Leaf and Onion (Allium Cepa Linn) Bulb Extracts as Antimicrobial Agents for Fish

Abstract The development of antibiotic-resistant pathogens due to the indiscriminate use of antibiotics has led to advocacy for the use of natural products in the treatment of fish diseases. The antimicrobial activity of methanolic and ethanolic extracts of walnut leaves and onion bulbs were evaluated against six pathogenic bacteria (Pseudomonas aeruginosa, Staphyloccocus aureus, Bacillus subtilis, Pseudomonas fluorescens, Escherichia coli, Samonella typhi) using the cup – plate me...

CHANGES IN THE PROTEIN AND FIBRE COMPONENTS OF CASSAVA AND YAM PEELS AFTER SOLID STATE FERMENTATION BY ASPHRCUlIMS NIGER AND RHIZOPUS SP

ABSTRACT Dried, milled cassava and yam peels were inoculated separately with A. nigermidRhizopus sp in solid state. The changes in crude protein (CP), crude fibre (CF), neutral detergent fibre (NDF), acid detergent fibre (ADF) and hemiccllulose were evaluated til 0. 4. X, and 10 days after inoculation. At. the end of the 10th day of fermentation with A. niger the crude protein of cassava peel meal (CPM) increased from 3.5% to 7.0% while that inoculated with Rhizopus sp increased to 5...

Assessment And Characterization Of Rhizobacteria In Petroleum-Polluted Soil In Umuahia

ABSTRACTPetroleum – polluted sites are disturbed ecosystem with scanty plants. Study was carried out in such sites to assess the area of its rhizobacterial status, particularly comparing that of the rhizospheres and non-rhizospheres in the site. The samples were suspended and serially diluted in physiological saline and inoculated on nutrient media by spread plates method. After incubation and isolation, the isolates were characterized by morphological examination, gram staining, biochemica...

Phytochemical Screening and Microbial Inhibitory Activities of Ficus Capensi

ABSTRACT Ficus plant components have application in traditional medicine because of the myriad uses they have been subjected to. The ease of application is based on the secondary metabolites this plant contains. The challenges faced by modern medicine especially in the complete cure of microbially-associated diseases through abrupt and unpredictable genetic mutations in the presence of conventional drugs informed the investigation of the microbial inhibitory activities of the stem, r...

Degradation of Polyamide-6 By Microbial Isolates from Solid Waste Dumpsites in Lagos State, Nigeria

ABSTRACT Polyamide-6 (also known as nylon-6) is one of the biodegradation-resistant synthetic polymers used in the manufacturing of commodity plastic materials. The environmental effects of the persistence of this material in landfill and on surface water bodies pose global problems that endanger public health. Knowledge of the microbial distribution and pattern of their interaction with these plastics will provide the biological resources and scientific basis for the development of...

Selection, Product Characteristics And Metabolite Spectrum Of A Common Starter Culture For Fufu And Usi Production

ABSTRACT Fermented cassava products like fufu and usi (edible starch) are important staple foods in many African homes. Natural fermentation time is usually long resulting in slower acidification process and inconsistent nutritional composition of products which could be overcome with the use of starter culture. However, most available starter cultures are used for single food fermentation and are uneconomical. This necessitates the development of a starter culture for multiple related ...

Comparison Of The Susceptibility And Pathology Of Velogenic Newcastle Disease Virus Infection In Broilers And Pullets

ABSTRACTThe greatest human nutritional problem in Nigeria is that of inadequate animal proteinin the diet of a large proportion of the population. The development and sustenance of thepoultry industry in Nigeria appears to be the fastest means of meeting human need for dietaryanimal protein supply. However, diseases constitute a major problem to the development ofthe poultry industry and Newcastle disease (ND) is the most important of these diseases.Newcastle disease is caused by a...

Spatial And Temporal Distribution Of Foot And Mouth Disease Virus In The Eastern Zone Of Tanzania

ABSTRACT This study was conducted to establish the spatial and temporal distribution of foot-andmouth disease (FMD) virus (FMDV) serotypes and evaluate the awareness of people on FMD in the eastern zone of Tanzania. Both observational prospective studies involving serological analysis, FMDV antigen detection and questionnaire survey, and retrospective study on FMDV antigen detection were used in this research. Seroprevalence of antibodies to the nonstructural protein 3ABC of FMDV and...

Disease Status And Risk Factors For Peste Des Petits Ruminants Along Tanzania-Burundi And Democratic Republic Of Congo Border

ABSTRACT An epidemiological study was carried out between September 2011 and February 2012 to determine the disease status of Peste des Petits ruminants (PPR) in western Kigoma region bordering Burundi and Democratic Republic of Congo (DRC). The study aimed at establishing the seroprevalence of PPR and identifying risk factors associated with the disease in three districts (Kasulu, Kibondo and Kigoma rural) of Kigoma region. The study also assessed the presence or absence of clinical ca...

Oral Candidiasis in Sudanese Cancer Patients Receiving Different of Treatments for different cancer types

This study was done to detect the prevalence of oral Candidiasis among Sudanese cancer patients with different cancer types who received different cancer treatment in Khartoumoncology hospital which formerly was known as Radio and Isotopes Centre of Khartoum (al Zarra Hospital) which recently named Khartoum Oncology Hospital. .A hundred oral swabs were collected from the patients with different age groups ranging from 2 to 83 old, 66\100 were males and 34\100 were females....

Insecticide Resistance Status Of Anopheles Gambiae Breeding In Stagnant Water Bodies In Lagos, Nigeria

ABSTRACT Anopheles gambiae, the major Afro-tropical malaria vector is resistant to pyrethroid insecticide and this is threatening the impact of malaria control efforts using insecticides. In this study, the major malaria vector species from stagnant water bodies and their susceptibility status to pyrethroid insecticide was determined in some areas of Lagos state, Nigeria. Anopheles larvae were sampled from three areas of Lagos, namely Akoka, Idiaraba and Okobaba and raised to adultho...

Evaluation Of HIV Testing Methods And Development Of HIV Testing Algorithms In Lagos, Nigeria

ABSTRACT The absence of regulatory control of HIV test kits in use, non-availability of HIV testing algorithm and absence of regular and constant evaluation programme for HIV testing kits stimulated the authors' curiosity to carry out both operational and experimental studies on the commercially available HIV test devices circulating in the Nigerian market. A scientific approach to address the setbacks in HIV testing methods contending with HIV serodiagnosis and surveillance, as well...

Enrichment And Molecular Characteristization Of Atrazine Degrading Actinomycetes Isolated From Polluted Nigerian Commercial Farmlands

ABSTRACT Microbes capable of degrading atrazine were isolated by traditional enrichment technique from composite soil samples collected from four agricultural farmlands with long history of atrazine use in Nigeria. The estimated atrazine degrading populations from Obasanjo, Ladipo Daniel, Agbowa - Ikosi and Itokin farms were 1.6 x 10* cfu/mg, 8.0 x 10^cfu/mg, 5.0 x 10* cfw/mg and 1.2 x 10 cfu/mg of the soil samples respectively. The soil sample from Obasanjo farm was selected for fur...


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