ABSTRACT
The greatest human nutritional problem in Nigeria is that of inadequate animal protein
in the diet of a large proportion of the population. The development and sustenance of the
poultry industry in Nigeria appears to be the fastest means of meeting human need for dietary
animal protein supply. However, diseases constitute a major problem to the development of
the poultry industry and Newcastle disease (ND) is the most important of these diseases.
Newcastle disease is caused by a ND virus (NDV) which is a Paramyxovirus. The commonest
strain of NDV in Nigeria is the velogenic, viscerotropic NDV which is the most virulent
among the five pathotypes. Chickens are the most susceptible of all the avian species;
however the relative susceptibility of various types of chicken to velogenic NDV infection has
not been investigated. The objective of this study is to compare the susceptibility, clinical
signs, gross and histologic lesions, haematological and serum protein profile changes,
distribution and persistence of lesions of velogenic Newcastle disease virus KUDU-113 in
broilers and pullets experimentally infected at 10 weeks of age. Thirty broilers and 30 pullets
were inoculated intramuscularly with 0.1ml of a velogenic Newcastle disease virus (NDV)
strain (KUDU-113) with a median EID50 of 105.46 per ml. Clinical signs were first observed in
the pullet on day 2 post inoculation (PI) which were mainly depression, ruffled feathers,
whitish diarrhoea, prostration, tucking of the head under their wings, paralysis of legs and
wings and withdrawal from feed. In broilers, signs were first observed on day 3 PI, which
were withdrawal from feed, depression, jerking of head, neck and head tremor, generalized
spasm and recumbence, ruffled feathers and greenish diarrhoea. Weight loss was highly
significant (P 0.05) difference was observed in the pullets. There
were no significant (P > 0.05) differences in total white blood count, heterophil, and
lymphocytes counts in both infected broilers and pullets. There were no significant (P > 0.05)
differences between the infected and control in the total serum protein values on day 4 PI in
broilers. However, the total serum protein value of the infected pullets was significantly (P 0.05) on day 4 PI. The above observation
shows that differences in weight loss and lesion severity were higher in broilers than in
pullets.
IFEANYICHUKWU, O (2021). Comparison Of The Susceptibility And Pathology Of Velogenic Newcastle Disease Virus Infection In Broilers And Pullets. Afribary. Retrieved from https://afribary.com/works/comparison-of-the-susceptibility-and-pathology-of-velogenic-newcastle-disease-virus-infection-in-broilers-and-pullets
IFEANYICHUKWU, ONYEMA "Comparison Of The Susceptibility And Pathology Of Velogenic Newcastle Disease Virus Infection In Broilers And Pullets" Afribary. Afribary, 14 May. 2021, https://afribary.com/works/comparison-of-the-susceptibility-and-pathology-of-velogenic-newcastle-disease-virus-infection-in-broilers-and-pullets. Accessed 04 Nov. 2024.
IFEANYICHUKWU, ONYEMA . "Comparison Of The Susceptibility And Pathology Of Velogenic Newcastle Disease Virus Infection In Broilers And Pullets". Afribary, Afribary, 14 May. 2021. Web. 04 Nov. 2024. < https://afribary.com/works/comparison-of-the-susceptibility-and-pathology-of-velogenic-newcastle-disease-virus-infection-in-broilers-and-pullets >.
IFEANYICHUKWU, ONYEMA . "Comparison Of The Susceptibility And Pathology Of Velogenic Newcastle Disease Virus Infection In Broilers And Pullets" Afribary (2021). Accessed November 04, 2024. https://afribary.com/works/comparison-of-the-susceptibility-and-pathology-of-velogenic-newcastle-disease-virus-infection-in-broilers-and-pullets