PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA

David Ombugadu 9 PAGES (4557 WORDS) Dissertation
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PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC 

PATIENTS IN JOS, NIGERIA 

Ombugadu, D.O1

, Oladele O.V1,2, Onuoha, S. C3* Omisope , O4

 and Ani, A1

1Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B 2084 Jos , Plateau State, Nigeria; 

2Department of Educational Services, Universal Basic Education, P.M.B 163 Garki Abuja, Nigeria. 3Department of 

Biotechnology, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria. 4Department of Chemical Pathology, Obafemi 

Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State 

*Correspondence: sconuoha@yahoo.com; Tel: +2348032385682 

ABSTRACT 

Helicobacter pylori is a helical shaped gram negative microaerophilic bacterium, that can inhabit various areas of the stomach. 

The study was carried out to determine the prevalence of Helicobacter pylori infection among dyspeptic patients attending 

Endoscopy unit, Jos University Teaching Hospital (JUTH). The prevalence of H pylori; antibodies in plasma and antigen in stool 

samples of 80 patients examined was studied using ELISA (DIA PRO, Italy) and ICA (BIOTEST China) respectively. Socio￾demographic and clinical information was obtained through the assistance of attending gastroenterology staff. Blood grouping 

was also performed by slide agglutination test for all patients. Helicobacter pylori IgG antibodies were detected in plasma of 28 

(35%) patients of which 27 patients out of the sero-positive cases were antigen positive while Helicobacter pylori antigen was 

detected in the stool of 31 (38.8%) patients of which 27 patients out of the antigen positive cases were also seropositve. No 

significant association was found between Helicobacter pylori and age, sex, ABO blood group, economic status, source of water 

and consumption of alcohol. Thus, Helicobacter pylori seropositivity with respect to blood groups was found to be 32.6%, 46.7%, 

33.3% and 33.3% in blood groups O, B, A and AB respectively, while Helicobacter pylori stool antigen test positive results was 

found to be 33.3%, 33.3%, 46% and 39.5% in blood groups O, B, A and AB respectively. Hence, no statistical association was 

found between Helicobacter pylori infection and blood groups of the patients (P>0.05). However, marital status was 

significantly associated with Helicobacter pylori antibody test (P<0.05). There is need for government to encourage people about 

the Helicobacter pylori screening test since it is one of the etiologic agent of ulcer. 

Keywords: Helicobacter pylori, Jos, Peptic ulcer, Prevalence. 

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APA

David, O (2019). PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA. Afribary.com: Retrieved April 26, 2019, from https://afribary.com/works/david-ovey-ombugadu-publiction

MLA 8th

Ombugadu, David. "PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA" Afribary.com. Afribary.com, 07 Feb. 2019, https://afribary.com/works/david-ovey-ombugadu-publiction . Accessed 26 Apr. 2019.

MLA7

Ombugadu, David. "PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA". Afribary.com, Afribary.com, 07 Feb. 2019. Web. 26 Apr. 2019. < https://afribary.com/works/david-ovey-ombugadu-publiction >.

Chicago

Ombugadu, David. "PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA" Afribary.com (2019). Accessed April 26, 2019. https://afribary.com/works/david-ovey-ombugadu-publiction