ABSTRACT
An outbreak of African Swine Fever (ASF), characterized by a mortality of 50 to
100% in various herds, was diagnosed among free-ranging domesticated pigs
in Delta State, Nigeria, in August 1998. The etiological confirmation of ASF
was made by virus isolation, PCR and sequencing of a 280 base pair fragment
of the major capsid protein (VP72) gene. Experimental infection of pigs with
infected blood resulted in pyrexia, which peaked two to four days postinfection,
followed by death in five to six days postinfection. Postmortem examination
revealed widespread hemorrhage, congestion and edema of tissues. The
lymph nodes, spleen, liver and kidneys showed marked focal random necrosis
and loss of lymphocytes from the splenic and lymphoid follicles. There was
an acute orchitis with massive neutrophilic and macrophage infiltrates into the
intertubular connective tissue. Meningitis and focal hemorrhages were observed
in the brain and spinal cord. The outbreak was believed to be a continuation of
an eastward spread of ASF from neighboring Benin, which began the previous
year (1997
Otesile, E (2021). Field and Experimental Investigations of an Outbreak of African Swine Fever in Nigeria. Afribary. Retrieved from https://afribary.com/works/field-and-experimental-investigations-of-an-outbreak-of-african-swine-fever-in-nigeria
Otesile, E.B. "Field and Experimental Investigations of an Outbreak of African Swine Fever in Nigeria" Afribary. Afribary, 23 Apr. 2021, https://afribary.com/works/field-and-experimental-investigations-of-an-outbreak-of-african-swine-fever-in-nigeria. Accessed 21 Nov. 2024.
Otesile, E.B. . "Field and Experimental Investigations of an Outbreak of African Swine Fever in Nigeria". Afribary, Afribary, 23 Apr. 2021. Web. 21 Nov. 2024. < https://afribary.com/works/field-and-experimental-investigations-of-an-outbreak-of-african-swine-fever-in-nigeria >.
Otesile, E.B. . "Field and Experimental Investigations of an Outbreak of African Swine Fever in Nigeria" Afribary (2021). Accessed November 21, 2024. https://afribary.com/works/field-and-experimental-investigations-of-an-outbreak-of-african-swine-fever-in-nigeria