Cell Biology and Genetics Research Papers/Topics

Comparison of vitronectin and fibronectin as substrates during the culture of human embryonic stem cells

Abstract: The feeder free culturing of pluripotent stem cells aims to eliminate the use of mouse embryonic fibroblasts (MEFs) as substrate during in vitro culturing. Here, the potential of fibronectin and vitronectin to keep stem cells undifferentiated was compared using two different stem cell lines (HUES1 and HUES7). Cells were cultured on vitronectin and fibronectin for 3 weeks. Results showed that cells cultured in fibronectin appear to adhere slightly well initially while those in vitro...

Genetic and Environmental Influences on Human Behavioral Differences

ABSTRACT Human behavioral genetic research aimed at characterizing the existence and nature of genetic and environmental influences on individual differences in cognitive ability, personality and interests, and psychopathology is reviewed. Twin and adoption studies indicate that most behavioral characteristics are heritable. Nonetheless, efforts to identify the genes influencing behavior have produced a limited number of confirmed linkages or associ...