ABSTRACT Chikungunya is a viral disease caused by Chikungunya virus (CHIKV) that is transmitted to humans by infected Aedes aegypti and Ae. albopictus mosquitoes. The objective of this study was to determine the seroprevalence of Chikungunya infection among febrile patients seeking healthcare in Mzuzu City, Malawi. Blood samples were collected during 2019 from outpatients attending Mzuzu Central Hospital who presented with fever but who were malaria and sepsis negative. Sera from outpatients...