Abstract The search for new drugs to combat infectious diseases has stimulated the interest of scientists globally due to emergence of Multi Drug-Resistant (MDR) microorganisms. Indigenous medicinal plants are potential reservoir of bioactive compounds from which new active drugs could be obtained, but are yet to be adequately exploited. This study was therefore designed to screen for new bioactive compounds from some indigenous medicinal plants against selected MDR microorganisms. Harungana...
ABSTRACT Contamination of land and water bodies by crude oil and refined petroleum products is a major challenge worldwide. Indiscriminate disposal of crankcase oil into the environment has increased hydrocarbon pollution in Nigeria. Microorganisms have been identified as major contributors in fighting pollution. The remediation ability of bacteria isolated from hydrocarbon contaminated organic rich soil has not been fully investigated. This research was designed to study in-situ genera and ...
ABSTRACT The presence of Antibiotic-Resistant Bacteria (ARB) in water sources and treated drinking water is an emerging public health issue. Antibiotic resistance genes and mobile genetic elements (integron and gene cassettes) have been reported as bases of resistance in ARB. Available data on ARB in southwestern Nigeria are based on phenotypic studies. Information on molecular basis of resistance in ARB is necessary to determine the mode of resistance transfer among bacteria. This research w...
ABSTRACT The need for meat preservation cannot be overemphasised. However, existing methods of meat preservation including the use of artificial preservatives have toxic side effects. There is a dearth of information on the use of Lactic Acid Bacteria (LAB), which is known as good preservatives for food, in the preservation of meat. Hence, the aim of this study was to examine the use of Pediococcus acidilactici and low temperature in improving the quality of beef, chicken and turkey meat sam...
Abstract Fossil fuel, a main but dwindling energy source for automobiles, causes emission of environment unfriendly oxides of carbon. These contribute substantially to greenhouse gases which bring about climate change. There is therefore the need for sustainable source of energy like ethanol an environmental friendly bioenergy. Hence this study was aimed at the fermentation of cocoa pod husk for ethanol production. Isolates of yeast were obtained from sun-dried Cocoa Pod Husk (CPH), subjecte...
ABSTRACT Vulvovaginitis is an inflammation of the vulva and vagina caused by bacteria, fungi, viruses, parasites and allergy. The condition results in reduction in mating ability, infertility, abortion and death of the affected animals with resultant economic loss to the livestock industry. Although mycoplasmas have been isolated from cases of vulvovaginitis, their role as sole causative agents and in the pathogenicity of the disease have not been investigated in goats in Nigeria. The aim of...
ABSTRACT Maize, Zea mays is extensively cultivated in Nigeria with estimated total grain yield of 1.37 million tonnes per year. The maize by-product which includes the cob is readily available. This project was designed to convert maize cob to value-added products in broiler feed through microbial degradation using batch fermentation. One hundred and fifty kilogrammes of maize cob samples were collected from four dump sites in a farmers’ market in Oyo town. Bacteria and fungi were isolate...
ABSTRACT Antimicrobial resistance is fast becoming a global concern in both healthcare settings and in the community due to the rapid emergence of multi drug resistant organisms. High proportions of enterobacteria have developed resistance to the commonly prescribed antimicrobial drugs. Comprehensive data upon which to advocate control interventions are scanty. Hence this study determined the Molecular Epidemiology of ESBL producing enterobactericeae from three Tertiary Hospitals in Southern ...
ABSTRACT The roots and seeds of Moringa oleifera were analysed for their nutritional, antinutritional and antimicrobial activities on Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis, Streptococcus fecalis, Escherichia coli and Candida albicans. Quantitative phytochemical analysis showed the presence of 0.57% and 1.17% oxalates, 4.02% and 2.66% phytic acid, 1.92% and 3.99% alkaloid, 65.47 mg/100 g and 109.12 mg/100 g tanins for the roots and seeds respectively. Proximate a...
The main aim of this research was to characterize the enterobacterial uropathogens with respect to drug resistance in Awka, south-eastern Nigeria. The following enterobacterial uropathogens isolated from patients attending Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka were studied: E.coli (58), Salmonella spp. (15), K. pneumoniae (14), Citrobacter freundii (10) and Enterobacter aerogenes(3). Their antibiotic susceptibility patterns against major classes of antibiotics were e...
Aims: To investigate the susceptibility pattern Salmonella enterica strains to selected antibiotics and extract of Dalbergia latifolia as well as their combinatory effect on (multi-drug resistant) MDR salmonella. Place and Duration of Study: Faculty of Pharmacy, University of Ibadan, Nigeria from October 2012-May 2013. Methodology: In this study, a total of 11 clinical isolates of Salmonella enterica strains were screened in vitro against five antibiotics (ampicillin, amoxycillin, chloramph...
ABSTRACT Paenibacillus species are opportunistic pathogens that tend to cause infections in immunocompromised individuals, it is increasingly becoming implicated in human infections but its role in animal farms is not well elucidated, this study is therefore aimed at determining the prevalence of this organism in farm animals, its molecular characterization as well as its antibiotic sensitivity profile. A total of 138 fecal samples were analyzed using standard aerobic and anaerobic culture me...
ABSTRACT This study was carried out to isolate, characterize and identify Aeromonas spp. from Irrigation water and vegetables. Water and vegetable samples were collected and analyzed for physicochemical and microbiological analysis. Physicochemical parameters such as pH, Temperature, Total Dissolved Solid (TDS), Dissolved Oxygen and Biological Oxygen Demand were determined using standard methods for water samples only. Microbiological parameters such as Total Coliform count (TC), Faecal ...