ABSTRACT
Schistosoma haematobium infects school children in areas where the disease is endemic. This study was carried out to determine the reliability of IgG Enzyme-Linked Immunosorbent Assay (ELISA) as an immunodiagnostic tool, using whole antigen derived from Schistosoma eggs. Children of school going age living in Ipogun village, in south western Nigeria; a schistosomiasis endemic community; were used in this study. The sensitivity of the IgG ELISA in detecting positive cases was 68.0% and there was a significant correlation (P < 0.05) between IgG titres and the intensity of infection. However, the specificity was 59.3%, slightly lower than the sensitivity. Results from this study shows that IgG ELISA can be used as a diagnostic tool for determining S. haematobium infection, as it provides an evidence for the intensity of the infection in the infected individuals.
Oniya, M & Omosun, Y (2021). IgG Enzyme-Linked Immunosorbent Assay (ELISA) for immunodiagnosis of Schistosoma haematobium infected subjects living in an endemic Nigerian village. Afribary. Retrieved from https://afribary.com/works/igg-enzyme-linked-immunosorbent-assay-elisa-for-immunodiagnosis-of-schistosoma-haematobium-infected-subjects-living-in-an-endemic-nigerian-village
Oniya, M and Y Omosun "IgG Enzyme-Linked Immunosorbent Assay (ELISA) for immunodiagnosis of Schistosoma haematobium infected subjects living in an endemic Nigerian village" Afribary. Afribary, 05 Apr. 2021, https://afribary.com/works/igg-enzyme-linked-immunosorbent-assay-elisa-for-immunodiagnosis-of-schistosoma-haematobium-infected-subjects-living-in-an-endemic-nigerian-village. Accessed 25 Apr. 2024.
Oniya, M, Y Omosun . "IgG Enzyme-Linked Immunosorbent Assay (ELISA) for immunodiagnosis of Schistosoma haematobium infected subjects living in an endemic Nigerian village". Afribary, Afribary, 05 Apr. 2021. Web. 25 Apr. 2024. < https://afribary.com/works/igg-enzyme-linked-immunosorbent-assay-elisa-for-immunodiagnosis-of-schistosoma-haematobium-infected-subjects-living-in-an-endemic-nigerian-village >.
Oniya, M and Omosun, Y . "IgG Enzyme-Linked Immunosorbent Assay (ELISA) for immunodiagnosis of Schistosoma haematobium infected subjects living in an endemic Nigerian village" Afribary (2021). Accessed April 25, 2024. https://afribary.com/works/igg-enzyme-linked-immunosorbent-assay-elisa-for-immunodiagnosis-of-schistosoma-haematobium-infected-subjects-living-in-an-endemic-nigerian-village