Research Papers/Topics in Biological Science

Investigating Conditions That Modulate Pyrazinamide Susceptibility in Mycobacterium Tuberculosis

ABSTRACT Tuberculosis (TB) remains one of the major life-threatening infectious diseases of public health concern globally. Its treatment is long and complex, requiring a cocktail of four drugs administered for six months. Pyrazinamide (PZA) is a cornerstone drug in the treatment regimen for tuberculosis that has contributed to reducing the treatment time from nine to six months. PZA is a pro-drug that is converted to its active form, pyrazines acid (POA) by the bacterial enzyme nicotin...

A Study Of The Reproductive Biology Of The Catfish, Chrysichthys Nigrodigitatus (Lacepede) In Nigeria

ABSTRACTThe Catfish, Chrysichthys Nigrodigitatus (Lacepede) is widely distributed in Nigeria.

N Vitro Investigation Of The Relationship Between Schistosomiasis And Prostate Cancer

ABSTRACT Schistosomiasis is a neglected tropical disease that affects 200 million people and accounts for 100, 000 deaths annually. In endemic geographical areas, schistosomiasis has been implicated as an etiological agent in the pathogenesis of bladder, colorectal and renal carcinoma largely due to chronic infection of tissues with Schistosoma eggs. Several studies have also reported cases of association between Schistosoma infection and prostate cancer, one of the most common cancers ...

Phytochemical Analysis Of Cleome Viscosa.

ABSTRACT Cleome viscosa Linn (Capparaceae) commonly known as “wild or dog mustard” is an annual sticky herb found as a common weed all over the plains of India and through the trophics of the world. The whole plant and its parts (Leaves, pods and roots) are widely used in traditional and folkloric systems of medicine. Cleome viscosa were extracted with and all these extract were screened for the presence of various metabolites (primary and secondary) including proteins, carbohydra...

Modulatory Effects Of The Crude Methanol Leaf Extract Of Cissampelos Owariensis On Some Biochemical Parameters In Bleomycin-Induced Lung Fibrosis In Male Wistar Rats

ABSTRACT Antioxidants have been shown to play protective role in the treatment of bleomycin-induced lung fibrosis. The goal of the study was to determine the effect of Cissampelos owariensis (CO) leaves, an alkaloid rich antioxidant on BLM-induced lung fibrosis in rat models. The CO (UIH22559) leaves were extracted using methanol and fractionated using vacuum liquid chromatography (VLC) to obtain the ethyl-acetate fraction (EAF) and methanol fraction (MEF). The active component of CME wa...

Influx Of Unqualified Teachers In Teaching Biology In Secondary Schools In Sokoto Metropolis.

ABSTRACT This study aimed at investigating the influx of unqualified teachers in teaching Biology in secondary school in Sokoto metropolis. With the view of finding solutions to improve the situation at stake. Criteria used in selecting the schools were random selection technique in which five schools were selected from each of the two (2) local government areas of the Sokoto metropolis, namely (Sokoto North and Sokoto South respectively), as a sample for this research. Questionnaire wa...

A Study Of The Nutrition And Health Of Children In The Gold Coast A Field And Laboratory Study

INTRODUCTION Despite wide interest in the nutrition and health of children in underdeveloped areas of the world, countries in Africa have been neglected by individuals and groups in the United States as sites for dietary and health studies. Reasons for this doubtless lie elsewhere than in a lack of interest. Such study not only offers the possibility of providing information needed by the indigenous population, but also information concerning the nutritive needs of children in relation ...

Deconstructing Invasion Phenotype Switching In Plasmodium Falciparum

ABSTRACT The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. The Dd2 and W2mef strains of P. falciparum have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neuraminidase-treated erythrocytes. Following an observation of increasing ability of Dd2 to invade neuraminidase-treated cells when cultured for several weeks...

Effect Of Two Kinds Of Solvent On Chemical Composition Of Cymbopogon Citratus Oil

ABSTRACT The experiment was designed to determine the effect of two different solvent (N-hexane and petroleum ether) on chemical composition of lemongrass oil. The oil was extracted from lemongrass using Nhexane and petroleum ether using soxhlet extraction method. The chemical composition of essential oil obtained were analyse using GC-MS machine. The result shows 4.4% of oil were obtained from lemongrass using N-hexane and 4.9% were obtained using petroleum ether. The composition anal...

Antinutritional Composition Of Securidaca Longepedunculata (Violet Tree)

ABSTRACT The antinutritional composition of leafs and stem bark s. longepedunculata were investigated using standard analytical methods. The leafs and stem bark of S. longepedunculata was air dried and the sample was pulverized for the determination of anti-nutritive contents. The antinutritional continents viz phytate, oxalate, nitrate and cyanide were determined in this investigation. Nitrate content was significantly (p

Evaluation Of Storage Control Point And Implicated Pathogens On Fast Moving Consumer Goods - Ogun And Lagos States As Case Study

ABSTRACT Ensuring food safety to protect public health remains a significant challenge in both developing and developed countries and food borne illness prevention system will depend on the extent of food safety control in place through food production, processing and distribution, keeping food at safe temperature and using safe water and raw materials. These stages of production are some of the important points determining food safety. The high level of bacterial contamination leading t...

Evaluation Of Some Nutritional, Physicochemical And Phytochemical Parameters Of Dioscorea Rotundata (White Yam) Flesh And Peels Exposed To Four Different Storage Patterns In Nigeria.

ABSTRACT The hue and cry of food insecurity in Nigeria prompted the curiosity of this study. This study investigates the evaluation of some nutritional, physicochemical and phytochemical parameters on Dioscorea rotundata (white yam) flesh and peels exposed to four different storage patterns in Nigeria. Four storage patterns and 20 tubers of yam were used for this study. The yams were grouped into the four storage patterns: Open Sided, Yam Barn, Heap on Floor and Platform Storage, and th...

Comparism Analysis Between Microscopy And Filariasis Strip Test (FTS)

ABSTRACT Lymphatic filariasis (LF) is caused by infection with threadlike worms called Wuchereria bancrofti. There had been different methods of diagnosing Filariasis. The two major diagnosing method is the Filariasis Test strip and the Microscopy test. This project is to compare the efficiency between the Microscopy test and Filariasis Test Strip (FTS) Night blood sampling method collected between the hours of 10pm – 2am and Filariasis test strip is done same hours using 2 drop of bl...

Assessment Of Coastal Ecosystems In The Greater Cape Three Points Area Towards Its Designation As Marine Protected Area In Ghana

ABSTRACTCoastal ecosystems sustain local and national fisheries livelihoods through a range of ecosystem services (ES) they provide. Five of these coastal ecosystems, located in two communities within the Greater Cape Three Points (GCTP) area—Princess Town (PT) and Cape Three Points (C3P)—were assessed to develop a scheme for establishing Marine Protected Area (MPA). To conduct an integrated assessment, the study employed the Community Participatory Mapping and Assessment of ecosystems an...

Management Of Indigenous Medicinal Plants In Nigeria Using Phenological Information

ABSTRACTAvailable information on medicinal plants indicates habitat loss and has heightened the need for more proactive conservation strategies. Conservation efforts in this direction resulted in an ecopharmacological survey in the West African sub-region by three countries (Nigeria, Ghana and Republic of Benin) to assess frequently used medicinal plants. The result of the socio-economic study based on utilization pattern regionally was used to produce a list of ten topmost frequently used...


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