ABSTRACT
( :modon dactyl on (Leaf) is a type of perennial grass that possesses great medicinal values.
\•IOJ·eover. medicinal plants are the important source of potentially useful structures for the
development of novel antimicrobial agents. Historically, plants have provided a source of the
development for novel drugs and plant derived drugs which have made large contributions to
human health and well-being. Till now very few plants have been scientifically proved by
di !Tcrent researchers for their medicinal potential but the therapeutic ability of number of plants
arc still unknown. In this study, two different solvents (Ethanol and water) were used for
extraction. These used to investigate the phytochemical constituents of the plant were used to
extract the bioactive compounds from the leaf of Cynodon dactyl on to screen the antibacterial
activity against infectious disease causing bacterial pathogen (Escherichia coli also known as E.
coli) using Agar well diffusion method. Antimicrobial study of ethanol and aqueous extracts
showed antimicrobial activity against the tested pathogen. Antimicrobial activity showed due to
presence of bioactivc compounds in both extracts. Ethanolic extract of C:vnodon dactyl on had a
mean zone of inhibition of24.3±0.6 and 20.3±0.6 against the susceptible and resistant strains of
F. coli respectively and aqueous extract of Cynodon dactyl on had a mean zone of inhibition of
I ').3 t0.6 and 16.3ci·0.6 against the susceptible and resistant strains of E. coli respectively. The
standard positive control had a mean zone of inhibition of 47.5±0.9 and 43.2±0.3 against the
'lrsccptiblc and resistant strains of E. coli respectively.
Research, S. (2022). KAMPALA INTERNATIONAL UNIVERSITY- (WESTERN CAMPUS) ISHAKA BUSHENYI. Afribary. Retrieved from https://afribary.com/works/kampala-international-university-western-campus-ishaka-bushenyi
Research, SSA "KAMPALA INTERNATIONAL UNIVERSITY- (WESTERN CAMPUS) ISHAKA BUSHENYI" Afribary. Afribary, 16 Aug. 2022, https://afribary.com/works/kampala-international-university-western-campus-ishaka-bushenyi. Accessed 23 Nov. 2024.
Research, SSA . "KAMPALA INTERNATIONAL UNIVERSITY- (WESTERN CAMPUS) ISHAKA BUSHENYI". Afribary, Afribary, 16 Aug. 2022. Web. 23 Nov. 2024. < https://afribary.com/works/kampala-international-university-western-campus-ishaka-bushenyi >.
Research, SSA . "KAMPALA INTERNATIONAL UNIVERSITY- (WESTERN CAMPUS) ISHAKA BUSHENYI" Afribary (2022). Accessed November 23, 2024. https://afribary.com/works/kampala-international-university-western-campus-ishaka-bushenyi