Pro- and anti-inflammatory cytokines mediate the progression of severe anemia in malaria-infected children: A prospective study

Background

Severe Plasmodium falciparum malarial anemia is still the principal cause of death in children in underdeveloped countries. An imbalance between proinflammatory and anti-inflammatory cytokines is associated with malaria progression. This study evaluated circulating levels of selected inflammatory cytokines among malaria-infected children in Ghana.

Methods

This case-control study was conducted at Tamale Teaching Hospital, Ghana. One hundred and twenty children with malaria and 60 controls, aged 12−144 months were selected from April to July, 2023 for the study. Malaria was diagnosed through microscopy, full blood count was measured using hematology analyzer, and cytokines were measured using enzyme-linked immunosorbent assay.

Results

Malaria-infected children had higher tumor necrosis factor alpha (TNF-α) (p

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APA

Banyeh, D. & Nkansah, C (2024). Pro- and anti-inflammatory cytokines mediate the progression of severe anemia in malaria-infected children: A prospective study. Afribary. Retrieved from https://afribary.com/works/pro-and-anti-inflammatory-cytokines-mediate-the-progression-of-severe-anemia-in-malaria-infected-children-a-prospective-study

MLA 8th

Banyeh, Dr Moses, and Charles Nkansah "Pro- and anti-inflammatory cytokines mediate the progression of severe anemia in malaria-infected children: A prospective study" Afribary. Afribary, 08 Sep. 2024, https://afribary.com/works/pro-and-anti-inflammatory-cytokines-mediate-the-progression-of-severe-anemia-in-malaria-infected-children-a-prospective-study. Accessed 21 Nov. 2024.

MLA7

Banyeh, Dr Moses, and Charles Nkansah . "Pro- and anti-inflammatory cytokines mediate the progression of severe anemia in malaria-infected children: A prospective study". Afribary, Afribary, 08 Sep. 2024. Web. 21 Nov. 2024. < https://afribary.com/works/pro-and-anti-inflammatory-cytokines-mediate-the-progression-of-severe-anemia-in-malaria-infected-children-a-prospective-study >.

Chicago

Banyeh, Dr Moses and Nkansah, Charles . "Pro- and anti-inflammatory cytokines mediate the progression of severe anemia in malaria-infected children: A prospective study" Afribary (2024). Accessed November 21, 2024. https://afribary.com/works/pro-and-anti-inflammatory-cytokines-mediate-the-progression-of-severe-anemia-in-malaria-infected-children-a-prospective-study