Are sex differences in blood cell count and hemoglobin moderated by the 2D:4D ratio? A cross‐sectional study in a Ghanaian population
Background and Aims: There are sex differences in blood cell count and hemoglobin (HGB) in adulthood due to differences in the levels of circulating sex hormones. The second‐to‐fourth digit ratio (2D:4D) is the putative marker of prenatal hormone exposure. The 2D:4D or the right‐left difference (Dr‐l) are sexually dimorphic and are correlates of sex hormones in adulthood. The study sought to determine whether sex differences in adult blood cell count and HGB can be partly explained by...
Forensic science in Ghana: A review
The use of forensic science continues to grow across the world. In Ghana, major advancements took off in 2011, including the introduction of modern DNA profiling and the establishment of an automated fingerprint identification system. These developments have led to some positive impacts on the delivery of justice, including the exoneration of a wrongly incarcerated individual. However, a review of the policy-related aspects of forensic science shows gaps in legislation, governance, service pr...
Effects of Highly Active Antiretroviral Treatment on Complete Blood Count Parameters
Aim: This study assesses the effects of HAART on complete blood count parameters among HIV infected participants. Study Design: Case control study. Place and Methods: This study was conducted in Tamale, Ghana from August, 2016 to December, 2017. Methodology: A total of 300 HIV infected participants with ages ranging from 19–79 years, administered with HAART for at least 6 months were recruited. Pre-HAART administration (baseline) demographic and clinical information, with initial full bloo...
Hepatitis B and C Status and Associated Risk Factors among Migrant Female Head Porters [Kayayei] within La-Nkwantanang Madina Municipality, Ghana
Aim: This study was conducted to determine the knowledge, prevalence and associated risk factors of viral hepatitis among migrant female head porters (Kayayei) in La-Nkwantanang Madina municipality of the Greater Accra region, Ghana. Study Design: A descriptive cross-sectional study was conducted. Place and Duration of Study: The study was carried out at three market centers [Atima, LaNkwantanang and Madina markets] within the La-Nkwantanang Madina municipality of the Greater Accra region, Gh...
Effects of Highly Active Antiretroviral Treatment on Liver and Kidney Functions
Aim: This study assesses the effects of HAART on liver and renal functions in HIV infected individuals on HAART. Study Design: Cross sectional study. Place and Methods: This study was conducted in Tamale, Ghana from August, 2015 to November 2017. Methodology: A total of 300 HIV infected participants with ages ranging from 19 to 79 years who have been administered with HAART for at least 6 months were recruited. Pre-HAART administration (baseline) demographic and clinical information, with ini...
Single nucleotide polymorphisms in LCAT may contribute to dyslipidaemia in HIV‑infected individuals on HAART in aGhanaian population
Highly active antiretroviral therapy (HAART) is known to cause lipid abnormalities such as dyslipidaemia in HIV-infected individuals. Yet, dyslipidaemia may not independently occur as it may be worsened by single nucleotide polymorphisms (SNPs) in lecithin cholesterol acyltransferase (LCAT) and lipoprotein lipase (LPL). This case–control study was conducted in three-selected hospitals in the Northern part of Ghana. The study constituted a total of 118 HIV-infected participants aged 19–71 ...
Models for predicting height from percutaneous lengths of the ulna and femur in a Ghanaian population
This study aimed to develop predictive models from percutaneous femoral (PFL) and ulna (PUL) lengths for estimating height among a living Ghanaian population. This was a cross-sectional study involving 99 adults (males=52, females=47) between the ages of 19–31yrs. The height, femoral and ulnar lengths of all participants were measured twice using standard anthropometric methods. Regression predictive equation models were developed based on PFL, PUL, age and the combined PFL+PUL. p < 0.05 wa...
Neutrophil to Lymphocyte ratio versus Monocyte to Lymphocyte ratio in predicting hypertensive diseases of pregnancy
Background: The neutrophil to lymphocyte ratio (NLR) and the monocyte to lymphocyte ratio (MLR) are two systemic inflammatory indices with promising prognostic and predictive abilities for HDP. The study aimed to determine the abilities of the NLR and MLR in predicting HDP among pregnant women in Ghana. Methods: This was a case-control study that was carried out between September 2015 and May 2016 at the Bolgatanga regional hospital. The study involved 50 pregnant women of whom 60% (30/50) ha...
A comparative study of glycaemic variability using four different Point-of-Care Testing (POCT) devices
Background: Blood glucose measurement is a way of monitoring changes in glycaemia. Different point-of-care testing (POCT) glucose meters are on the market and hence there is an increase in variability of the results given by these meters. This study sought to measure the glycaemic variability using four different point-of-care glucose meters Methods: Four point of care glucometers namely; Accu-chek performer nano, OneTouch select plus flex, OneTouch Ultra 2 and Easy Check were used test blood...
Second to fourth (2D:4D) digit ratio and their relationships among a mother and child population in Ghana
The study aimed to determine the relationship between digit ratios among a mother–child population in Ghana. This was a cross-sectional study from December 2020 to April 2021 involving 272 mothers, their daughters (n= 132) and their sons (n= 140). The right (2D:4DR) and the left (2D:4DL) digit ratios were measured using computer-assisted analysis. The data were analysed in SPSS (v23) and GraphPad Prism (v8) at an alpha value of 0.05. The mean±SD age of the mothers was 23.9 ± 3.67 years wh...
Correlation between maternal variables and the onset and severity of preeclampsia [version 1; peer review: awaiting
Background: The study sought to determine the correlation between the onset and severity of preeclampsia (PE) and maternal sociodemographic variables: age, parity and body mass index (BMI); medical history: systolic blood pressure (SBP), diastolic blood pressure (DBP), and proteinuria; fasting lipids: total cholesterol (TCHOL), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and triglycerides (TRIG); liver enzymes: aspartate transaminase (AST), alanine transaminase (ALT) and gam...
The relationship between 2D:4D ratio and postpartum adult female variables in a Ghanaian population
Objectives: Postpartum hematological and anthropometric assessment is a requirement for optimal maternal and child health. The study aimed to determine the relationship between the 2D:4D ratio and postpartum hematological and anthropometric variables in adult females. Methods: The study was cross-sectional from December 2020 to April 2021 involving 272 postpartum adult females, aged between 18 and 36 years. The right (2D:4DR) and the left (2D:4DL) digit ratios were measured using computer-ass...
The relationship between offspring's 2D:4D ratio and postpartum maternal circulating testosterone, estradiol, and their indices in a Ghanaian population
Objectives: The 2D:4D ratio is influenced by prenatal testosterone (PT) and estrogen (PE) exposure in utero. This study sought to determine whether evidence of Manning's hypothesis can still be observed even in the postpartum period. We hypothesize that the offspring 2D:4D ratios will be inversely correlated with maternal postpartum circulating testosterone but positively correlated with estradiol. Methods: This study was conducted between December 2020 and April 2021 and was cross-sectional ...
Fire Incident Statistics in the Tamale Metropolitan Area in the Northern Region of Ghana: A Retrospective Study
The effect of a fire disaster is greater in developing countries due to inadequate 'firefighting preventive and support systems. There is therefore the need to analyze fire incident data to enable better fire safety and prevention strategies. The study was a retrospective cross-sectional study from January to June 2021. In all, 130 fire incident reports from 2017 to 2020 were collected. The data, consisting of 32 variables were analyzed using binary logistic regression. It was observed that f...
Sex estimation from the percutaneous lengths of the femur and the ulna in a Ghanaian population using discriminant function analysis
Sex estimation models form a vital part in Forensic human identification but they are usually population-specific. This study aimed to develop and test sex estimation models for a Ghanaian population using percutaneous lengths of the femur (FL) and ulna (UL). The study was cross-sectional from June to July 2020, involving 99 adults (male: 52, females: 47), aged between 19 and 31years. The lengths of the femur and ulna were measured using standard anthropometric techniques. All measurements we...
Doctorate
University for Development Studies
July 2018 to Present