Background: Breast cancer is the most common type of cancer among women in both
high-resource and low-resource countries. According to WHO Global Burden of Disease,
2004, breast cancer accounts for 16% of all female cancers with majority (69%) of breast
cancer deaths occurring in developing countries. Although breast cancer incidence rate is
said to be increasing worldwide, little is known about the determinants of the disease in
Africa and currently, there is no data available on breast cancer risk factors in Ghana.
There is therefore the need to identify potential risk factors for breast cancer among
Ghanaian women so as to tackle this public health burden with effective preventive
Objectives: The goal of this study was to identify risk factors that contribute to breast
cancer among women in Accra, Ghana; specifically to determine reproductive, hormonal
and behavioural factors contribution to breast cancer among a subgroup of women in
Methods: An unmatched case control study was conducted among breast cancer
patients at the Korle Bu Teaching Hospital from May to July, 2010. Using a systematic
random sampling, a total of 126 incident breast cancer patients were selected from the
hospital attendance register at the Korle Bu Teaching Hospital Breast Clinic. Controls
were relatives of the cases. Open and close-ended, self-administered questionnaires
were used to collect information on demographic, reproductive, hormonal, behavioural
and anthropometric factors.
Results: This study has contributed to new knowledge of breast cancer epidemiology in
Ghanaian women. Educational status, family history of breast cancer and smoking habits
were identified as the most significant risk factors among breast cancer patients. This
study found no statistically significant associations between hormonal risk factors and
Conclusions and recommendations: This study revealed that the potential risk factors for
breast cancer among Ghanaian women include educational status, family history of breast
cancer as well as smoking habits. Further investigations are recommended, probably a
population based study, to identify and establish the true contribution of each possible
risk factor that may be particularly important in the development of breast cancer in this
and other populations of African origin.
Keywords: breast cancer, reproductive risk factors, hormonal risk factors, behavioural risk factors
Edu, F (2021). RISK FACTORS FOR BREAST CANCER AMONG PATIENTS IN KORLE-BU TEACHING HOSPITAL: A CASE-CONTROL STUDY. Afribary.com: Retrieved April 15, 2021, from https://afribary.com/works/risk-factors-for-breast-cancer-among-patients-in-korle-bu-teaching-hospital-a-case-control-study
Frontiers, Edu. "RISK FACTORS FOR BREAST CANCER AMONG PATIENTS IN KORLE-BU TEACHING HOSPITAL: A CASE-CONTROL STUDY" Afribary.com. Afribary.com, 04 Apr. 2021, https://afribary.com/works/risk-factors-for-breast-cancer-among-patients-in-korle-bu-teaching-hospital-a-case-control-study . Accessed 15 Apr. 2021.
Frontiers, Edu. "RISK FACTORS FOR BREAST CANCER AMONG PATIENTS IN KORLE-BU TEACHING HOSPITAL: A CASE-CONTROL STUDY". Afribary.com, Afribary.com, 04 Apr. 2021. Web. 15 Apr. 2021. < https://afribary.com/works/risk-factors-for-breast-cancer-among-patients-in-korle-bu-teaching-hospital-a-case-control-study >.
Frontiers, Edu. "RISK FACTORS FOR BREAST CANCER AMONG PATIENTS IN KORLE-BU TEACHING HOSPITAL: A CASE-CONTROL STUDY" Afribary.com (2021). Accessed April 15, 2021. https://afribary.com/works/risk-factors-for-breast-cancer-among-patients-in-korle-bu-teaching-hospital-a-case-control-study