Evaluation of antimicrobial activities of crude ethyl

The purpose of this research work is to determine the antimicrobial activities of crude ethyl acetate and ethanolic extracts of Morinda lucida leaf, stem, and bark growing in Adekunle Ajasin University Botanical Garden against selected clinical isolates. The plant Morindal lucida falls under the family Rubiaceae known to have wide usage in traditional medicine. Morinda lucida is a tropical West African tree of medium-size about 18–25 m tall, the bark is grey to brown in color, flowers are white in color, the fruit is a drupe, seed is ellipsoid, yellowish and soft. The antibacterial potency of ethyl acetate and ethanolic extracts of Murinda lucida leaf, stem, and bark were tested against selected clinical isolates, the clinical isolates are Escherichia coli (ATCC 0157), Escherichia coli (ATCC 25922), Salmonella typhi, Candida albicans (ATCC  90029), Klebsiella pneumonia (ATCC 35657 ), Mycobacterium fortuitum (ATCC  6841). Mycobacterium smegmatis (ATCC 19420), Mycobacterium abscessus (ATCC 19977), Mycobacterium phlei (ATCC 19240), Staphylococcus aureus (ATCC 29213). Agar well diffusion method was used to measure the antibacterial activities of Morinda lucida against the clinical isolates. We observed that the, Morinda lucida has antimicrobial activity against the clinical isolates. It was also observed that, the ethanol extracts of leaf and bark has better antimicrobial activity compared to the ethyl acetate stem extract. But all the extracts exhibit various degrees of antimicrobial activities.