Research Papers/Topics in Medical Lab Science and Tech

Assessment of Sensitivity and Specifity Immunochromatograophy Test And ELISA for detecting Human Immunodeficiency Virus Antibodies among Screening Patients in Khartoum State

Abstract  Human Immunodeficiency Virus ( HIV) is global and serious problem , with increase in mortality and morbidity worldwide. This was prospective , descriptive and cross sectional study aimed to assess the level of HIV Ab using the ICT and ELISA for detecting Ab and Ag (p24) .It was conducted among Screening patient in Khartoum state (National Public Health Laboratory) from 1 April to 30 June (2015) on a total of eighty nine (n=89)to compare the sensitivity and specificity of immunochro...

Measurement of Complete Blood Count (CBC) in alcohol consumer – Khartoum 2014

Abstract This is a prospective case control study to investigate the effect of alcohol consumption on complete blood count (CBC) of alcohol consumers in Khartoum State from April to July 2014.The participants were 80 apparently healthy adult males; 50 of them are alcohol consumers and 30 are non-alcoholic (control).Their age was (41 ±7.3years).A questionnaire was constructed to obtain information about the participants after an informed verbal consent from all the participants. Ethical appr...

Molecular Basis of Immunological Dysfunction in People Living with HIV and AIDS in Enugu, Nigeria

ABSTRACT Molecular basis of immunological dysfunction in people living with HIV and AIDS was studied among HIV-positive people attending clinics at the University of Nigeria Teaching Hospital Ituku-Ozalla, Annunciation Specialist Hospital Emene, Mother of Christ Specialist Hospital and Enugu State University Teaching Hospital, all in Enugu metropolis. A total of 90 subjects recruited for the study were divided into three groups: 30 diagnostically positive HIV subjects (A), 30 HIV-positive sub...

Analysis of Heavy Metals in Pleurotus Tuberregium Sclerotia,Toxicity in Blood, Bone Marrow and Some Selected Organs of Albino Rats

ABSTRACT Pleurotus tuberregium is a common mushroom which is used as food or medicine, more commonly as a vegetable soup thickener. This study investigated the presence of heavy metals in wild samples of pleurotus tuberregium sclerotia consumed within our localities, compared the degree of heavy metal contamination of the samples, investigated the presence of heavy metals in the serum of albino rats due to its consumption and the effects of its consumption on blood, bone marrow, liver and kid...

Potential for the Prediction of Prostate Cancer Risk Using Haplotypes in Exon 5 of Klk2 Gene

ABSTRACT BACKGROUND: Prostate cancer is the most common neoplasia of middle aged men .Early detection is problematic due to the lack of marker that has high sensitivity and specificity. Our aim was to genetically predict the possibility of developing prostate cancer using haplotypes in exon 5 of kLk2 gene. We evaluated polymorphisms in human glandular kallikreins 2 (KLK2) genes because a protein product of this gene is known to be increased in prostate cancer. SUBJECTS AND METHODS: Blood samp...

Haemopoietic and Haematinic Property of the Leaf and Fruit Extract of Solanum Nigrum L (Spp Villosum) in Anaemic Albino Wistar Rats

ABSTRACT Anaemia is a global public health problem affecting both developing and developed countries with major consequences for human health as well as colonial and economic development. There is paucity of data on the use and type of medicinal plants that can be used to alleviate anaemia. Sequel to the fact that orthodox medicine can no longer give answers to our numerous different diseases in which anaemia is one of them. There is an increasing interest in the use of herbal products to sup...

Assessment of Tinea Infections Among Primary School Children in Aninri Local Government Area of Enugu State, Nigeria

Abstract Tinea infection is a common fungal infection that affects the superficial keratinized tissues of the body (skin, hair and nails). This study assessed tinea infections among primary school children in Aninri Local Government Area of Enugu State, Nigeria. Seven primary schools were selected for the study. Ethical approval was obtained from the Education and Health Departments of Aninri Local Government and informed consent also obtained from the parents of the pupils. A researcher-deve...

Immuno-Pathological Markers in Hiv/Aids Infection

ABSTRACT The AIDS pandemic and discovery of HIV, has produced a cohort of patients that thrust immunodeficiency and its associated infections into the lime light. Some opportunistic infections are indicators of HIV infection and are termed AIDS defining illnesses by the center for disease control and prevention. This study assesses the relationship between markers of HIV disease progression (AIDS defining illnesses) and CD4 lymphocyte count. Sputum samples of 234 HIV positive patients were an...

Hemostatic and Hematological Studies of Aqueous Extract of Bidens Pilosa in Wistar Rats

ABSTRACT Bidens pilosa L. (Asteraceae) also known as hairy beggar ticks, common names include; ‘Ogwunma’; 'Gyeya'(Igbo, Birom, Nigeria) and is one of the medicinal plant species worldwide. Among the Birom tribes in Plateau State, Nigeria Bidens pilosa is used as vegetable to prepare the local delicacy called ghote and also the sap from crushed leaves is used to speed up clotting of blood in fresh wounds. The aim of the study was to evaluate the effect of aqueous extract of Bidens pilosa l...

Physico – Chemical Evaluation of Water from Different Sources Commonly Consumed in Enugu Metropolis Southeast Nigeria

ABSTRACT Evaluation of physico-chemical substances in different water commonly used in Enugu metropolis were carried out between December, 2011 and November, 2012 to ascertain their respective concentrations. The work which is a survey study, would help to reveal the level of contamination if any, and to authenticate, if the water samples are safe for drinking purposes. The water samples consisted of bottled water, satchet water, tap water and well water. The pH, lead, zinc, copper and nitrat...

The Prevalence Of Human Cytomegalovirus Among Pregnant Women Attending Thika Level 5 District Hospital Kiambu County, Kenya

Abstract Cytomegalovirus (CMV) is a member of herpesviruses. It is one of the most common causes of congenital and prenatal infections. It is a ubiquitous virus with the ability to establish latency following primary infection, and can be reactivated particularly during episodes of immunosuppression. CMV infection of pregnant women, especially in the first trimester may lead to congenital abnormalities and is often associated with serious complications, such as microcephaly, mental retardatio...

Human Immunodeficiency Virus (Hiv) Prevalence Among Catha Edulis Forsk (Miraa) Users In Meru Region, Kenya

ABSTRACT Khat or miraa (Catha edulis Forsk (Celastraceae) chewing is known to be a widespread habit in among selected communities in Kenya. Since HIV/AIDS was declared a national disaster in Kenya in 1999, the disease has become an obstacle to both health and development of the people. Nevertheless, the use of substance including C. edulis has dramatically increased despite the serious concern on control of HIV infection. This study was aimed at determining the HIV prevalence and impact ...

Effect Of Blood Cupping (Al-Hijama) On Total Cholesterol, High Density Lipoprotein Cholesterol And Low Density Lipoprotein Cholesterol Levels

Abstract The word "hijama" is derived from "hajm" which means "sucking." cupping is the process of applying cups to various points on the body by removing the air inside the cups to form a vacuum. This study was carried out in Al- Almi for alternative medicine, Al-Rawabih charity organization for Al-Hijamah and Al-Madeina Al-Monwara clinic in Khartoum state; from April to August (2017), to detect the effect of Blood Cupping on Total Cholesterol, High density lipoprotein cholesterol (HDL-c) a...

Serodetection of Hepatitis C Virus Infection among Diabetic Patients Type 2 in Marawi Military Hospital at Northern State

Abstract Hepatitis C is an infectious disease caused by Hepatitis C virus (HCV) which affects the liver . The objective of this study was to determine the frequency of HCV among patients with Diabetes type 2 in Marawi Al skary Hospital at Northern State The study was conducted during the period between march to July 2017. A total of ninety (n=90) blood specimens were obtained from 48 males and 42 females diabetic patients .Five ml of blood was collected .Sera were obtained by centrifugation ...

Molecular Characterization and Serological Cut-off (Copro-Antigen ELISA) of Entamoeba Histolytica and Giardia Lamblia - Khartoum State

Abstract This study aimed to determine the molecular characterization and serological cut-off (Copro-Antigen ELISA) of E. histolytica and G. lamblia in Khartoum State. A crosssectional study was conducted in period between August, 2014 to August, 2017. Epidemiological and parasitological data were obtained and recorded. 300 stool samples were collected from all participants, (100 infected with E. histolytica, 100 infected with G. lamblia and 100 healthy individuals as control group). All sam...


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